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Flashcards in Review Deck (65):
1

Anticholinergic SE (Dryness, confusion)

"PANDAH on a TRIcycle"

  • Promethazine
  • Atropine
  • Neuroleptics (low potency)
  • Digoxin
  • Amantadine
  • H1 blockers
  • TCAs

2

Coronary Vasospasm

"META takes Cocaine"

  • Methamphetamines
  • Ergotamines
  • Triptans
  • Amphetamines
  • Cocaine

3

Cutaneous Flushing

VAND

  • Vancomycin
  • Adenosine
  • Niacine
  • Dihydropyridine CCBs

4

Dilated Cardiomyopathy

  • Doxorubicin 
  • Daunorubicin

5

Torsades de pointes

Rx?

13 CHaMP

  • Class IA sodium channel blockers
  • Class III potassium channel blockers
  • Chloroquine
  • Haloperidol
  • Macrolides
  • Protease Inhibitors

 

Rx for torsades: Push IV Magnesium

 

6

Agranulocytosis

3Cs, 2 thyroid drugs, Dap

  • Clozapine
  • Carbamaepine
  • Colchicine
  • PTU
  • Methimazole
  • Dapsone

7

Aplastic Anemia

CB MN for PTU

  • Chloramphenicol (gray baby)
  • Benzene
  • Methimazole
  • NSAIDs
  • PTU

8

Gray Baby Syndrome

Chloramphenicol

9

Hemolysis in G6PD-deficient patients

"eat Favas in PIINDANS country (red soiled area of Australia)"

  • Fava beans
  • Primaquine
  • Isoniazid, Ibuprofen
  • Naphthalene
  • Dapsone
  • high-dose Aspirin
  • Nitrofurantoin (UTIs)
  • Sulfonamides

10

Megaloblastic anemia

PMS no Zs

  • Phenytoin,
  • Methotrexate
  • Sulfa drugs
  • Zidovudine

 

11

Thrombocytopenia

 

  • Heparin (HIT)
  • H2 blockers (cimetidine)

12

Thrombosis

OCPs (especially if smoker >35 years old)

13

Pulmonary fibrosis

  • Bleomycin
  • Busulfan
  • Amiodarone (LFTs)

14

Acute cholestatic hepatitis 

Erythromycin estolate (don't give to patients with liver disease!)

15

Focal to massive hepatic necrosis

Kill your liver, HAVe A mushroom!

 

  • Halothane
  • Acetaminophen
  • Valproic acid
  • Amanita phalloides (mushroom toxin)

16

Hepatitis

Isoniazid (INH) 

17

Pseudomembranous Colitis

  • Any antibiotic but notoriously:
  • Clindamycin
  • Ampicillin

18

Adrenocortical insufficiency

Withdrawal of Corticosteroids

19

Gynecomastia

Booby's got SMACKED! 

  • Spironolactone
  • Marijuana
  • chronic Alcohol use
  • Cimetidine
  • Ketoconazole
  • Estrogens
  • Digitalis

20

Hot Flashes

  • Tamoxifen
  • Clomiphene

21

Hypothyroidism

  • Amiodarone (TFTs),
  • Lithium
  • Sulfonamides

22

Hyperglycemia

  • Niacin
  • Tacrolimus
  • Protease inhibitors

23

Fat redistribution

  • Steroids
  • Protease inhibitors
  • HIV breaks down fat and causes sunken in facial features (temporal wasting),
  • Insulin injections

24

Gingival hyperplasia

  • Phenytoin
  • Verapamil

25

Gout

Diuresis:

Diuretics and Nic cycles up pyramid with gout

  • Furosemide
  • Thiazides
  • Niacin
  • Cyclosporin
  • Pyrazinamide

26

Myopathies

PSyCHING myopathies will elevate CPK

  • Penicillamine
  • Statins
  • Colchicine
  • Hydroxychloroquine
  • INF-alpha
  • Niacin
  • Glucocorticoids

 

27

$ Osteoporosis

  • Corticosteroids (if on for 3 months, get on bisphosphonate)
  • Heparin

28

Photosensitivity

  • Sulfonamides
  • Amiodarone
  • Tetracycline

29

Steven-Johnson Syndrome

Seizure drugs, Cillins and Sulfas:

  • Seizure meds: Ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital.
  • Penicillin
  • Sulfas
  • Allopurinol

30

Drug-induced SLE

"SHIPP"

  • Sulfonamides
  • Hydralazine
  • INH
  • Procainamide
  • Phenytoin

31

Tendon rupture/cartilage damage

Fluoroquinolones

32

Nephrogenic DI

Rx for nephrogenic DI?

  • Lithium
  • Demeclocycline

Rx for DI - HCTZ, indomethacin, amiloride (add to lithium induced)

33

Fanconi syndrome - proximal tubular defect

  • Expired tetracycline
  • Heavy metal exposure
  • Wilson disease

34

Interstitial Nephritis

  • Methicillin
  • NSAIDS
  • Furosemide

35

Hemorrhagic Cystitis

  • Cyclophosphamide
  • Ifosfamide (MESNA can prevent urotoxic metabolite from injuring the bladder)

36

SIADH

  • Carbamazepine
  • Cyclophosphamide

37

Cinchonism (Dizziness + headache + vision changes + tinnitus)

  • Quinidine (Class IA)
  • Quinine

38

Reversible drug-induced parkinsons

  • Reserpine
  • Antipsychotics (haloperidol)
  • Metoclopramide
  • MTPT

39

Seizures

"I IBM WEPT from a seizure"

  • Isoniazid, Imipenem/cilastatin
  • Buproprion
  • Metoclopramide
  • Withdrawal: Benzos or Alcohol
  • Enflurane
  • evening Primrose oil
  • Tramadol

 

40

Tardive Dyskinesia

High Potency antipsychotics (Fluphenazine, Haloperidol)

41

Disulfiram-like reaction

"Drink Corona at Midnight and Suffer Post Binge"

  • Disulfiram
  • Certain Cephalosporins,
  • Metronidazole
  • First-generation Sulfonylureas
  • Procarbazine (Anti-cancer alkylating agent)

42

Nephrotoxic + Ototoxicity

Loop VAC

  • Loop diuretics
  • Vancomycin
  • Aminoglycosides
  • Cisplatin

 

43

Acetaminophen

N-acetylcystine (relenishes glutathione)

Toxic dose - 12g in 24 hours

Max recommended dose - 4g in 24 hours

44

Salicylates

Sodium Bicarbonate (alkalinize urine), dialysis

45

Amphetamines

NH4Cl (acidify urine)

(ammonium chloride)

Amphetamines are basic

46

Acetylcholinesterase inhibitors, organophosphates

Atropine, pralidoxime - regenerates acetylcholinesterase

47

Antimuscarinic, anticholinergic agents

Physostigmine salicylate

48

Beta blockers

Glucagon, Calcium, Atropine

49

Digitalis

Stop dig; Atropine

KLAM - Potassium, Lidocaine, Anti-dig Fab fragments, magnesium

50

Iron

Deferoxamine

51

Lead

CaEDTA, dimercaprol, succimer, penicillamine

52

Mercury, arsenic, gold

Dimercaprol (BAL), succimer

53

Copper, arsenic, gold

Penicillamine

54

Cyanide, from house fire or sodium nitroprusside OD

Nitrie, hydroxocobalamin, thiosulfate

55

Methemoglobin

Methylene blue, vitamin C

56

Carbon monoxide

100% O2, hyperbaric O2

57

Methanol

Fomepizole > ethanol, dialysis

58

Ethylene glycol (antifreeze)

Fomepizole > ethanol, dialysis

59

Opioids

Naloxone/naltrexone

Often baby is OD due to mother receiving opioids for pain management in pregnancy

60

Benzodiazepines

Flumazenil

61

TCAs

Sodium bicarbonate (plasma alkalinization)

62

Heparin

Protamine

63

Warfarin 

Vitamin K, fres frozn plasma

(Takes 3-5 days for clotting factos to come back online)

64

PA, streptokinase, urokinase

Aminocaproic acid

65

Theophylline 

(Tacycardia)

Beta-blocker