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Renal > Review > Flashcards

Flashcards in Review Deck (115)
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1

Where is renin secreted by?

kidneys

2

What causes renin to be secreted?

decrease in renal pressure/flow

3

What does renin bind and cleave too?

angiotensinogen

4

Where is angiotensinogen made?

liver

5

What does angiotensinogen form?

angiotensin I (inactive)

6

Where does angiotensin I get converted to angiotensin II?

lungs by ACE

7

What is the role of angiotensin II?

vasoconstriction

8

Where does angiotensin II bind?

receptor cells in the zone glomerulus of the adrenal gland which decreases aldosterone

9

Where does aldosterone bind?

principle cells in the collecting duct

10

What does aldosterone cause?

water and Na+ to be retained

11

Organs of the upper urinary tract

kidneys and ureters

12

Organs of the lower urinary tract

bladder and urethra

13

Pathway from blood to urine

kidneys - afferent arterial - glomerulus (podocytes) - bowman's capsule - proximal collecting duct - descending loop of henle - Loop of henle - ascending loop of henle - distal convoluted tubule - collecting duct - renal pelvis - ureter - bladder - urethra

14

Proximal tubule - Reabsorption

Na, K, Cl, H2O, HCO3, Glucose, Amino Acids

15

Proximal tubule - secretion

creatine, antibiotics, diuretics, uric acid

16

Descending limb of LOH - reabsorption

H2O

17

Ascending limb of LOH - reabsorption

Na, K, Mg, Ca, Cl

18

Distal convoluted tubule - reabsorption

Na, Cl, Ca, H2O

19

Distal convoluted tubule - secretion

K, H, Urea

20

Collecting duct - reabsorption

H2O

21

Proximal tubule - diuretics

carbonic anhydrase inhibitors, osmotic diuretics

22

descending LOH - diuretics

osmotic diuretics

23

ascending LOH - diuretics

loop diuretics

24

distal convoluted tubule - diuretics

thiazide/thiazide like, osmotic

25

collecting duct - diuretics

potassium sparing, osmotic

26

Stop taking potassium supplement when you switch to

potassium sparing diuretic

27

ACE - where is it?

lungs

28

ACE - what does it do?

converts angiotensin I to angiotensin II

29

Chronic glomerulonephritis - labs

UA - decrease SG,
PTH (elevated)

30

Chronic glomerulonephritis - presentation

Anemia
Pericarditis 2nd to uremia
taste change
foamy bubbly urine