Revision

Question 1

The spleen

Answer 1

has primary follicules
red and white pulp
contain germinal centres in infection with blood borne pathogens as a response to antigens
destroys redundant RBC

Question 2

complement pathway and opsonins

Answer 2

C3b is principle opsonin

all complement pathways converge here - results in membrane attack complex and lysis

Question 3

which cell contains a multi-segmented nucleus

Answer 3

neutrophil

Question 4

which cell is widely spread through the skin

Answer 4

Langerhans cell
in stratum spinosum part of epidermis
they’re APC

Question 5

what do NK cells detect

Answer 5

loss of MHC 1 proteins

Question 6

what contains peyer’s patches

Answer 6

MALT
non-capsulated aggregations of lymphoid tissue ijn GALT
made of B lymphoid tissue - contain germinal centres in an immune response

Question 7

what is a general filter of the blood

Answer 7

red pulp of the spleen

Question 8

site of completion of T cell maturation

Answer 8

medulla of the thymus

Question 9

CD4 Th2

Answer 9

assist in B cell proliferation

Question 10

CD4 Th1

Answer 10

activate macrophages

Question 11

what class are CD4 cells restricted to

Answer 11

MHC class 2

Question 12

humoral immune response

Answer 12

B cell interact with antigen
undergoing clonal selection
become Ab secreting cells
Ab bind to antigen = neutralisation/facilitate elimination