T lymphocyte activation

Question 1

What effect does co-stimulation have on T cells

Answer 1

affect surface of t cell, TCR come together.

Question 2

explain the importance of antigen presenting cells in the induction of T lymphocyte responses

Answer 2

Clonally select the T cell with the complementary TCR to the antibody - activating it
Done in lymph node
when DC meets antigen it enters lymph node
T cell circulates lymph, lymph node and blood
taken out by chemotaxis [move along epithelium - signal make integrin high affinity - bind to cell receptors and move into the tissue - chemokines determine where the cells go.] through High endothelial venules into lymph node
DC antigen activates T cell into effector
Tc/Th
memory