Revision session Flashcards
(25 cards)
Canine distemper virus cause immune suppression by what?
Canine distemper virus cause immune suppression by killing B and T lymphocytes
Which animals have IgY isotopes of antibody:
Which animals have IgY isotopes of antibody: birds and amphibians
Which of the following cytokines active nK cells and stimulates differentiation of th 1 cells
Which of the following cytokines active nK cells and stimulates differentiation of th 1 cells
IL-12
Which T helper cell type specifically enhances the neutrophil response:
Which T helper cell type specifically enhances the neutrophil response:
T helper 17 cells
No maternal IgG is transferred across the what type of placenta
No maternal IgG is transferred across the what type of placenta
epitheliochorial placenta
Which organs in the animals are affected by cytokines leading to an acute phase response?
Which organs in the animals are affected by cytokines leading to an acute phase response
brain and liver
This group of organism relies exclusively on innate immunity for protection from pathogens?
This group of organism relies exclusively on innate immunity for protection from pathogens
invertebrates
During a secondary immune response which ab isotope is predominate?
During a secondary immune response which ab isotope is predominate?
IgG
Peptides produced by processing of endogenous or cytosolic proteins are primarily present?
Peptides produced by processing of endogenous or cytosolic proteins are primarily present
at the cell surface on MHC I to CD8 T cells
Which of the following adaptive immune response leads to immunopathology during feline IP infection?
Which of the following adaptive immune response leads to immunopathology during feline IP infection?
humeral immunity
The fc region of an ab is important for?
The fc region of an ab is important for?
binding complement and fc receptors on immune cells
To become activated and differentiate T cells require?
To become activated and differentiate T cells require?
ag signalling via single or multiple T cells receptors and co stimulation
Newborn kittens younger than 6 weeks old often can’t be successfully vaccinated because?
Newborn kittens younger than 6 weeks old often can’t be successfully vaccinated because?
maternal ab inhibit newborn’s immune response
During a bacterial infection animals will show?
During a bacterial infection animals will show?
elevated neutrophil count (neutrophilia)
Which signals from Th 1 cells help macrophages to kill intracellular bacteria within vesicles?
Which signals from Th 1 cells help macrophages to kill intracellular bacteria within vesicles?
release of IFNy and expression of CD40L
When the innate immune system comes into contact with an ag what detects it?
When the innate immune system comes into contact with an ag what detects it?
pattern recognition receptors
Which ab function involves ab forming a bridge between an infected cells and NK cell?
Which ab function involves ab forming a bridge between an infected cells and NK cell?
ab dependant cellular cytotoxicity
The elimination of microbes that persist inside the macrophages vesicle is caused by?
The elimination of microbes that persist inside the macrophages vesicle is caused by?
macrophage activation with help from Th1 cells
Microfold or M cells are specialised epithelial cells found above?
Microfold or M cells are specialised epithelial cells found above?
peter patchers GALT
Which immune cells are directly kill virally infected cells through the release of cytotoxic granules?
Which immune cells are directly kill virally infected cells through the release of cytotoxic granules?
cytotoxic CD8 T cells and natural killer cells
Component of which complement pathway can interact with bound ab?
Component of which complement pathway can interact with bound ab?
classical pathway
CD8 cytotoxic T cells are most effective at targeting which type of pathogen?
CD8 cytotoxic T cells are most effective at targeting which type of pathogen?
viruses
When an ab or IG is anchored surface of a B cell it is called?
When an ab or IG is anchored surface of a B cell it is called?
B cell receptors (BCR)
What is the predominate ab isotope in the respiratory tract?
What is the predominate ab isotope in the respiratory tract?
IgA
