Rhabdoviridae

Question 1

Rhabdoviridae is ___ shaped

Answer 1

bullet

Question 2

What are the two important viruses of Rhabdoviridae?

Answer 2

Rabies virus

Vesicular stomatis virus

Question 3

Rabies virus is very ____in the environment

Answer 3

Fragile

Question 4

Rabies is non _____, meaning that the rabies virus does not destroy ____

Answer 4

non cytopathic

Rabies does not destroy neurons

Question 5

What are the inclusion bodies associated with Rabies?

Answer 5

Negri bodies

Question 6

What rhabdoviridae virus is cytopathic, has no inclusion bodies and is stable in the environment?

Answer 6

Vesicular stomatitis virus

Question 7

What Rhabdoviridae virus is non cytopathic, has inclusion bodies, and is fragile in the environment?

Answer 7

Rabies virus

Question 8

Envelope of Rhabdoviridae contains the ___ protein

Answer 8

G

(glycoprotein)

Question 9

Spike in the envelope induces the ____ antibodies

Answer 9

neutralizing

Question 10

Rhabdovirus produces ____ particles during replication at a high percentage

Answer 10

defective interfering particles (DI)

Question 11

Rhabdoviruses are ____, and inactivated by UV light

Answer 11

thermoliable

Question 12

What is the etiological agent for Rabies virus?

Answer 12

genotype 1 Lyssavirus

Question 13

There is only one serotype of rabies so the _____ will protect against all rabies strains

Answer 13

vaccine

Question 14

____ are very susceptible to rabies

Answer 14

rodents

Question 15

____ are highly susceptible to Rabies and are very epidemiologially important because they carry a very high titer of virus in their saliva and the virus is longer lived in these species

Answer 15

Skunks

Question 16

Dogs and humans are ____ susceptible to rabies

Answer 16

moderatly

Question 17

What strains are there for Genotype 1 rabies virus?

Answer 17

Skunk strains- 2

Arctic and red fox strain

Gray fox strain

Dog and coyote strain

Raccoon strain

Question 18

Rabies is extremely liable when exposed to _____

Answer 18

UV light

Question 19

Most common mode of transmission in rabies virus?

Answer 19

bites

scratches

Question 20

Rabies can also be transmitted via _____ but is not common due to the fragility of the virus

Answer 20

aerosol inhalation

*very common in bat cats!

Question 21

In north america, what kinds of bats are important for the transmission of rabies?

Answer 21

fruit

insectoviorous

Question 22

What animal accounts for most cases of cattle infection with rabies?

Answer 22

skunks

Question 23

____ are reservoirs of rabies viruses

Answer 23

bats

Question 24

____ is very important in maintaining the virulence of the rabies virus

Answer 24

moisture

*dry saliva cannot transmit virus

Question 25

True/False: Rabies develops rapidly in hosts

Answer 25

False \*it is slow developing

Question 26

Rabies virus first multiplies in _____ cells

Answer 26

muscle

Question 27

True/Fale: there is no viremia in rabies virus

Answer 27

True

Question 28

In the brain, rabies first multiplies in the ____ system

Answer 28

limbic \*why you see behavioral changes in animal- "furious" form with biting ect.

Question 29

What is the cause of death in Rabies virus?

Answer 29

respiratory paralysis

Question 30

The most important organ epidemiologically in Rabies is the \_\_\_\_\_

Answer 30

salivary glands \*only time the animal can trasmit rabies

Question 31

True/False: In rabies the animals develop hydrophobia because they are afraid of water

Answer 31

False They are not able to swallow

Question 32

What is a characteristic sign of rabies in cattle?

Answer 32

Bellowing salivation

Question 33

Where is the virus multiplying during the paralytic form of Rabies?

Answer 33

neocortex \*no longer showing aggression

Question 34

What is the best way to prevent rabies virus?

Answer 34

vaccination

Question 35

Not all Rabies virus positive brains show \_\_\_\_

Answer 35

negri bodies

Question 36

neutralizing antibodies are directed against ___ protiens

Answer 36

G

Question 37

What is the etiological agent of Vesicular stomatis?

Answer 37

Vesiculovirus

Question 38

What pathological finding is associated withe vesicular stomatitis?

Answer 38

ulcers

Question 39

What hosts will you find vesicular stomatitis in?

Answer 39

cattle, horses and swine

Question 40

True/False: Vesicular Stomatitis is a worldwide disease

Answer 40

False \*not a world wide disease

Question 41

What serotype is most important in Vesiular Stomatitis?

Answer 41

New Jersey serotype \*most virulent and widely distributed

Question 42

Is there cross protection between the New Jersey and indiana serotypes of Vesicular Stomatitis?

Answer 42

No

Question 43

How is vesicular stomatitis transmitted?

Answer 43

direct contact arthropods

Question 44

Vesicular Stomatitis causes loss of ____ and horses and there is a very short \_\_\_

Answer 44

condition short immunity

Question 45

Do we vaccinate in Vesicular Stomatitis?

Answer 45

No \*Quarantine for 30 days

Question 46

Bovine ephemeral fever is cause by what etiological agent?

Answer 46

Bovine ephemerovirus

Question 47

Bovein Ephemeral fever is ____ to north america

Answer 47

exotic

Question 48

What drops dramatically with Bovine ephemeral fever?

Answer 48

milk production

Question 49

Bovine Ephemeral fever has 100% ____ transmission

Answer 49

arthropod \*mosquito transmission- Aedes

Question 50

What Disease is has Neutrophilia with a left shift?

Answer 50

Bovine Ephemeral fever