Rheum

Question 1

Causes of additive arthritis

Answer 1

OA, RA

Question 2

Causes of migratory arthritis

Answer 2

Gonococcal, rheumatic fever

Question 3

Causes of intermittent arthritis

Answer 3

Gout, Pseudogout, SLE

Question 4

Which diagnosis? Pencil in cup deformity

Answer 4

Psoriatic arthritis

Question 5

Which diagnosis? Squaring of vertebral bodies, enthesophytes

Answer 5

Ankylosing spondylitis

Question 6

Which diagnosis? Associated with uveitis, conjunctivitis, oral ulcers

Answer 6

Reactive arthritis

Question 7

Which diagnosis? Positively birefringent crystals

Answer 7

CPPD

Question 8

Target uric acid level on allopurinol

Answer 8

<6

Question 9

Which diagnosis? Associated with painless pustular lesions

Answer 9

Gonococcal arthritis

Question 10

Tx septic arthritis: staph/strep (3)

Answer 10

nafcillin, oxacillin, cephazolin

Question 11

Tx septic arthritis: Neisseria

Answer 11

Ceftriaxone (+ azithromycin for chlamydia)

Question 12

Tx septic arthritis: Pseudomonas

Answer 12

3rd-4th cephalosporin + aminoglycoside

Question 13

Tx septic arthritis: culture negative

Answer 13

3rd-4th cephalosporin +/- vancomycin

Question 14

Tx RA First-line

Answer 14

Methotrexate

Question 15

C/I Methotrexate (3)

Answer 15

Liver disease, lung disease, immunosuppression

Question 16

Tx RA Second-line

Answer 16

Hydroxychloroquine, Leflunomide, Sulfasalazine

Question 17

MOA Methotrexate

Answer 17

Folic acid antimetabolite

Question 18

Tx RA exacerbations (2)

Answer 18

NSAIDs, steroids

Question 19

Lupus Mucocutaneous (4)

Answer 19

Malar, discoid, mouth ulcers, photosensitivity

Question 20

Lupus Internal Findings (4)

Answer 20

Pleuritis/pericarditis, renal disease, seizures, arthritis

Question 21

Lupus Lab criteria

Answer 21

Antibodies, ANA, Hematologic

Question 22

Lupus antibodies

Answer 22

Anti-smith, anti-dsDNA, anti-phospholipid

Question 23

Dx Antiphospholipid Syndrome

Answer 23

1 Clinical + 1 Lab

Question 24

Antiphospholipid syndrome clinical criteria (2)

Answer 24

Recurrent pregnancy loss, thrombosis

Question 25

Antiphospholipid syndrome lab criteria (3)

Answer 25

Lupus anticoagulant, Anticardiolipin antibody, Beta-2-glycoprotein 1 antibody

Question 26

Dx Ankylosing Spondylitis

Answer 26

MRI SI Joint

Question 27

Tx Ankylosing Spondylitis

Answer 27

TNF-alpha Inhibitors

Question 28

TNF-alpha Inhibitors (3)

Answer 28

Infliximab, etanercept, adalimumab

Question 29

Which diagnosis? acute lower extremity arthritis, usually resolving within 4-6 months

Answer 29

Reactive Arthritis

Question 30

Tx reactive arthritis

Answer 30

NSAIDs (first-line)

Question 31

Tx Axial enteropathic arthritis or psoriatic arthritis

Answer 31

TNF-alpha Inhibitors

Question 32

Tx Psoriatic arthritis

Answer 32

MTX

Question 33

Polymyositis/Dermatomyositis Antibodies (3)

Answer 33

Anti-Jo1, Anti-Mi-2, Anti-SRP

Question 34

Tx Poly/Dermatomyositis (Acute)

Answer 34

Prednisone

Question 35

Tx Poly/Dermatomyositis (Maintenance) (2)

Answer 35

MTX or azathioprine

Question 36

CREST

Answer 36

Calcinoshs, Raynaud, Esophageal Dysmotility, Sclerodactyly, Telangiectasias

Question 37

Scleroderma Antibodies

Answer 37

Anti-Scl-70 (topoisomerase 1)

Question 38

Which diagnosis? Red sclerae, enlarged parotid glands, periodontal disease

Answer 38

Sjogren Syndrome

Question 39

Dx Sjogren Syndrome

Answer 39

Salivary Gland Biopsy

Question 40

Tx Sjogren Syndrome

Answer 40

Parasympathomimetics (pilocarpine, cevimeline

Question 41

Tx Fibromyalgia (first-line)

Answer 41

Exercise, CBT

Question 42

Which diagnosis? Anti-U1-RNP

Answer 42

Mixed Connective Tissue Disease

Question 43

Which diagnosis? spiking fevers, arthralgias, salmon-colored rash

Answer 43

Adult Onset Still Disease

Question 44

Dx Giant cell arteritis

Answer 44

Temporal artery biopsy

Question 45

Tx Giant cell arteritis

Answer 45

Steroids (even before biopsy)

Question 46

Which disease? Claudication, vascular bruits, and aortic regurgitation in young women

Answer 46

Takayasu Arteritis

Question 47

Which disease? Necrotizing vasculitis leading to aneurysm formation; presenting with mesenteric ischemia, muscle pain, renal disease, and skin findings

Answer 47

Polyarteritis Nodosa

Question 48

Dx Polyarteritis Nodosa

Answer 48

Aneurysms on imaging, biopsy

Question 49

Which disease? upper respiratory tract, lower respiratory tract and renal involvement?

Answer 49

Granulomatosis with Polyangiitis

Question 50

Antibody in Granulomatosis with Polyangiitis

Answer 50

c-ANCA

Question 51

Tx Granulomatosis with Polyangiitis

Answer 51

Steroids, cyclophosphamide

Question 52

Which disease? asthma, allergic rhinosinusitis, glomerulonephritis, mononeuritis multiplex

Answer 52

Eosinophilic Granulomatosis with Polyangiitis

Question 53

Tx Eosinophilic Granulomatosis with Polyangiitis

Answer 53

Steroids, cyclophosphamide

Question 54

Which disease? Glomerulonephritis, pulmonary hemorrhage, palpable purpura, arthralgias/myalgias

Answer 54

Microscopic Polyangiitis

Question 55

Tx Microscopic Polyangiitis

Answer 55

Steroids, cyclophosphamide

Question 56

Labs in cryoglobulinemia

Answer 56

+RF, C4 decrease out of proportion to C3

Question 57

Tx Cryoglobulinemia (3)

Answer 57

Steroids, rituximab, plasma exchange