Rheum

Question 1

Saddle nose

Answer 1

GPA

[can also be sarcoidosis]

Question 2

Azathioprine plus allopurinol = ?

Answer 2

pancytopenia

Question 3

Which drug causes reactivation of latent TB

Answer 3

TNF alpha inhibitor (etanercept, infliximab)

Question 4

What DMARD causes interstitial pneumonitis

Answer 4

methotrexate

Question 5

What DMARD causes black tarry stools

Answer 5

NSAIDs

Question 6

what DMARD is nephrotoxic

Answer 6

Gold, penicillamine

Question 7

what are the traid of Sx of Behcet’s Syndrome

Answer 7

Visual loss, mouth ulcers and genital ulcers

Question 8

trimethoprim + methotrexate = ?

Answer 8

fatal

acute megaloblastic pancytopenia

Question 9

boy with back pain and a sore eye

Answer 9

AS

Question 10

what is PMR linked with

Answer 10

temporal arteritis

Question 11

antibodies seen in SLE

Answer 11

anti-Sm
Anti-DNA binding
ANA
Anti Ro + La

Question 12

antibodies seen in RA

Answer 12

Anti-CCP

RF

Question 13

antibodies seen in Sjogrens Syndrome

Answer 13

Anti Ro and La

Question 14

antibodies seen in Limited Systemic Sclerosis

Answer 14

Anti-centromere

Question 15

antibodies seen in Diffuse Systemic Sclerosis

Answer 15

Anti-Scl-70

Question 16

antibodies seen in mixed CTD

Answer 16

Anti-RNP

Question 17

antibodies seen in polymyositis

Answer 17

Anti-Jo-1

Question 18

antibodies seen in anti-phospholipid syndrome

Answer 18

Anti-Cardiolipin

Lupus anti-coagulant

Question 19

side effects of methrotrexate

Answer 19

liver cirrhosis
myelosuppression
pneumonitis

Question 20

side effects of sulfasalazine

Answer 20

rashes

oligospermia

Question 21

side effects of hydroxychloroquine

Answer 21

retinopathy

corneal deposits

Question 22

side effects of prednislone

Answer 22

cushings 
osteoporosis 
impaired glucose tolerance 
hypertension 
cataracts

Question 23

side effects of gold

Answer 23

proteinuria

Question 24

side affects of penicillamine [can be used in Wilson’s disease also]

Answer 24

proteinuria [membranous glomerulonephritis]

exacerbation of myathenia gravis

Question 25

side effects of infliximab

Answer 25

reactivation of TB

Question 26

allergy to what drug may be a contraindication to starting sulfasalazine

Answer 26

aspirin

Question 27

what antibiotics are risk factor for tendon rupture

Answer 27

quinones i.e. ciprofloxacin

Question 28

what heart problem is Ehler-Danlos associated with

Answer 28

aortic regurgitation

Question 29

what is ANA linked with

Answer 29

SLE, scleroderma, Sjögren’s syndrome, polymyositis/dermatomyositis, mixed connective tissue disease, drug-induced lupus, and autoimmune hepatitis

Question 30

what type of hypersensitivity reaction is SLE

Answer 30

Type 3 = immune complexes

Question 31

what is Felty Syndrome

Answer 31

splenomegaly and neutropenia in a patient with rheumatoid arthritis

Question 32

what are drugs that can cause drug-induced lupus

Answer 32

isoniazid, phenytoin, hydralazine

Question 33

antibodies seen in drug-induced lupus

Answer 33

ANA positive | Anti-histone antibodies

Question 34

If a FRAX score > 10% = ?

Answer 34

get a DEXA scan

Question 35

first line treatment for Raynouds

Answer 35

Calcium Channel Blocker

Question 36

Periarticular erosions on x-ray = ?

Answer 36

RA