Rheumatologic Pleuropulmonary Disease Flashcards Preview

MS and Rheum > Rheumatologic Pleuropulmonary Disease > Flashcards

Flashcards in Rheumatologic Pleuropulmonary Disease Deck (7)
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1

Scleroderma (SS) pathophysiology mediators

IL-8
TNF
MIF1alpha
RANTES
Endothelin-1
TGF-beta

2

IL-8 in SS

early
neutrophil attractant and activator

3

TNF in SS

early
neutrophil attractant and promoter of neutrophil-endothelial binding

4

MIF1alpha in SS

promoter of neutrophil chemotaxis

5

RANTES in SS

acronym for "Regulated on Activation Normal T cell Expressed and Secreted"

T cell recruiter and activator

6

Endothelin-1 in SS

vasoconstriction

7

TGF-beta

late
promoter of fibroplasia