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Year 6 Cross Section > Rheumatology > Flashcards

Rheumatology Flashcards

(55 cards)

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1
Q

problems with joints

A

OA
Crystal arthritis (gout, pseudogout)
RA
Spondyloarthritis (AS, Psoriatic arthritis, IBD, reactive arthritis)

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2
Q

multi-system problems

A
  • connective tissue disease (SLE, Sjogrens, systemic sclerosis)
  • vasculitis (takayasu’s, GCA, polyarteritis nodosa, HSP)
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3
Q

bone/soft tissue problems

A
  • metabolic bone disease (osteoporosis, osteomalacia)
  • inherited disorders of connective tissue
  • soft tissue disease (Bursitis, tendiopathy)
  • fibromyalgia
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4
Q

signs of OA

A

Herberden’s
Bouchard’s
Squaring at base of thumb
joints: DIP, PIP, CMC

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5
Q

mx of OA

A

pain management
physio
aids for daily living
injection
surgery

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6
Q

which joints are affected in RA?

A

wrist joints
MCP joints
PIP joints
>10 joints in total

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7
Q

management of RA

A
  • analgesic
  • NSAID
  • steroid prep
  • csDMARDS (e.g. methotrexate)
  • biological DMARDs
  • tsDMARDS (e.g. JAK inhibitors)
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8
Q

X-ray findings of AS

A

bilateral sacroiliitis
sclerosis
erosive damage
fusion of joint
reduced joint space

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9
Q

treatment of AS

A

doesn’t respond to conventional DMARDs
use biologicals e.g. TNFa or IL17

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10
Q

signs of psoriatic arthritis

A

small joints of PIP/DIP
psoriatic nail changes (oncycholysis, pitting, subungal hyperkeratosis)

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11
Q

connective tissue diseases are all…

A

ANA +ve

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12
Q

dsDNA

A

SLE

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13
Q

ENA

A

Sjogrens (Ro, La)

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14
Q

cytoplasmic

A

Myositis (t-RNA, Jo1)

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15
Q

limited vs diffuse sclerosis

A

limited = skin changes limited to forearm/calf, more distal and to peri oral area
= anti-centromere

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16
Q

cANCA is against

A

enzyme proteinase 3

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17
Q

pANCA is against

A

myeloperoxidase

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18
Q

score system for osteoporosis and treatment

A

FRAX score
Tx: bisphosphonate, anti-RANK ligand PTH analogue

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19
Q

RA disease monitoring

A

Disease Activity Score 28 (DAS28)
CRP monitoring

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20
Q

X-ray loss of joint space RA vs OA

A

RA: loss of joint spaces in proximal joints
OA: loss of joint spaces in distal joints

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21
Q

RA X-ray changes (LESS)

A

loss of joint space
erosions (periarticular)
soft tissue swelling
subluxation and deformity

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22
Q

X-ray findings in Gout

A

punched out erosion
rat bites

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23
Q

X-ray in AS

Study These Flashcards
A

Bamboo spine (squaring of lumbar vertebrae)
Dagger sign (supraspinatus tendon ossification)
Syndesmophytes

24
Q

Abs in SLE

Study These Flashcards
A

ANA
anti-dsDNA
anti-Smith

25
monitoring SLE
anti-dsDNA titres C3 and C4 levels ESR
26
anti-RNP
mixed connective tissue diseases
27
diffuse systemic sclerosis organ involvement
fibrosis of GIT, lung, cardiac, renal
28
what are the myositis panel of Abs
Anti-Jo1 Anti-Mi2 Anti-SRP
29
ANCA -ve small vessel vasculitides
Goodpasture's Cryoglobulinaemia HSP
30
Wegener's symptoms
URT: rhinitis, saddle nose LRT: haemoptysis and cough Renal: rapidly progressive glomerulonephritis
31
Churg Strauss symptoms
eosinophilia asthma rapidly progressive glomerulonephritis
32
Microscopic polyangiitis symptoms
palpable purpura glomerulonephritis haemoptysis
33
associations of pseudogout
hypothyroidism chondrocalcinosis haemochromatosis hyperparathyroidism
34
lifestyle changes in SLE
sunscreen stop oestrogen containing meds avoid smoking exercise
35
definition of polyarthritis
>5 joints
36
causes of symmetrical arthritis
RA, OA
37
causes of asymmetrical arthritis
reactive psoriatic
38
L2
hip flexion
39
L3
knee extension knee jerk
40
L4
foot inversion and dorsiflexion knee jerk
41
L5
great toe dorsiflexion
42
S1
foot eversion ankle jerk
43
definition of OA
degenerative joint disorder progressive loss of hyaline cartilage
44
extra RA signs on hands
ulnar deviation of fingers dorsal subluxation of ulnar styloid
45
scoring system for RA
DAS28
46
Differential diagnosis of rheumatoid hands
psoriatic chronic crystal arthritis
47
management of pseudogout
analgesia NSAIDs steroids
48
skin changes of reactive arthritis
keratoderma blenorrhagica (plaques on soles/palms) circinate balanitis (penile ulceration)
49
CREST skin involvement
face, hands, feet
50
organ fibrosis in diffuse systemic sclerosis
GI Lung Cardiac Renal
51
Extra skin findings in dermatomyositis
shawl sign (macular rash) mechanic hands (painful rough skin, cracking of fingertips)
52
antibodies in SLE
ANA dsDNA anti-Smith
53
large vessel vasculitides
GCA Takayasu
54
medium vessel vasculitides
polyarteritis nodosa Kawasaki
55
PMR symptoms
pain/stiffness no weakness

Year 6 Cross Section (23 decks)

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