Rheumatology

Question 1

In Fibromyalgia how long is the pain present before diagnosis can be made

Answer 1

3 Months

Question 2

What Rheum condition presents with characteristics such as: Stiff after sleep, worsened by cold, stress and activity, Pain in back and neck worse.

Answer 2

Fibromyalgia

Question 3

What conditions are associated with fibromyalgia?

Answer 3

Chronic fatigue syndrome, restless leg syndrome, Depression and anxiety, Irritable bladder, IBS, Migraines, painful periods,

Question 4

What Rheum condition presents with characteristics such as: Flu-like illness followed by; weakness, back and neck pain and stiffness, tender muscle and tendons

Answer 4

Fibromyalgia

Question 5

What is the Goal of pharmacological intervention in fibromyalgia

Answer 5

To aid associated symptoms like depression and difficulty sleeping

Question 6

Name three management options for fibromyalgia

Answer 6

CBT, exercise and heated pools

Question 7

what drugs are associated with drug induced lupus?

Answer 7

chlorpromazine, Methyldopa , Hydralazine, Isoniazid, d-penicillamine, minocycline

Question 8

What Infection is linked to causing SLE

Answer 8

Epstein barr virus

Question 9

what is the characteristics of the SLE rash

Answer 9

malar (butterfly) rah precipitated by sunlight and sparing of the naso-labial folds. erythmatous and well demarcated

Question 10

What Cardiac conditions are linked with SLE

Answer 10

pericarditis, HTN and endocarditis

Question 11

name three Respiratory conditions associated with SLE

Answer 11

Fibrosing alveolitis, Pulmonary Emboli

Question 12

What renal conditions are linked with SLE

Answer 12

nephritis and GN

Question 13

What antibody should be tested for diagnosis of drug induced lupus

Answer 13

anti-histone

Question 14

What antibody Is 30% prevalent in polymyositis and dermatomyositis

Answer 14

Anti-Jo

Question 15

What antibody Is prevalent in scleroderma

Answer 15

anti-centromere (70%)

Question 16

ds-DNA is 70 % prevalent in what condition

Answer 16

SLE

Question 17

what antibody is most sensitive to SLE

Answer 17

ANA

Question 18

what antibodies is most specific to SLE

Answer 18

Anti-dsDNA and Anti smith

Question 19

what antibodies are prevent in both SLE and Sjögren’s

Answer 19

Anti-Ro and anti La

Question 20

What antibodies are most prevalent in sjögrens

Answer 20

Anti-Ro and anti La

Question 21

anti-sm antibodies are more prevalent in what ethnic group in SLE patients

Answer 21

black African

Question 22

What Rheum condition presents with characteristics such as: dry eyes, dry mucosa, fatigue and arthralgia

Answer 22

Sjögren’s

Question 23

name three conditions associated with Sjögren’s

Answer 23

autoimmune thyroid disease, coeliacs, Primary bilary cirrhosis

Question 24

What cancers are associated with Sjögren’s

Answer 24

B-call lymphoma, non-hodgkins lymphoma and parotid tumour

Question 25

What clinical test contributes to diagnosis of Sjögren's?

Answer 25

Schirmers test

Question 26

What result in the Schirmers test is suggestive of Sjögren's ?

Answer 26

less than 5mm/5mins

Question 27

What results in antibody testing is suggestive of enteropathic arthritis

Answer 27

Seronegative

Question 28

what antigen positive is heavily associated with enteropathic arthritis ?

Answer 28

HLA-D27

Question 29

What Rhuem condition presents with only Symmetrical proximal muscle weakness and Skin lesions

Answer 29

Dermatomyositis

Question 30

What three cancers are most associated with Dermatomyosistis

Answer 30

Lung, breast and ovarian

Question 31

Photosensitive macular rash over back and shoulders is indicative of what Rheum condition

Answer 31

Dermatomyositis

Question 32

It is a reddish-purple rash on the upper eyelids that is usually bilateral is what rash

Answer 32

Heliotrope rash

Question 33

A heliotrope rash is in what condition

Answer 33

juvenile dermatomyositis

Question 34

What systemic vasculitis affects medium sized vessels

Answer 34

Polyarteritis Nodosa and Kawasakis disease

Question 35

What systemic vasculitis affects large sized vessels

Answer 35

Giant cell arteritis and takayasus arteritis

Question 36

Name 4 conditions that are ANCA positive

Answer 36

Microscopic polyangitis, granuloatosis with polyangitis, eosiniophillic granulomatosis with polyangitis, HSP

Question 37

What vasculits presents with: sudden blindness, jaw claudication and limb pain

Answer 37

Giant cell arteritis

Question 38

What vasculits presents with: reduced BP and pulse in one arm and renal dysfunction

Answer 38

takayasus arteritis

Question 39

What vasculits presents with: foot drop, abdomen pain and haemorrhage, gangrene, glomeronephritis, rash

Answer 39

polyarteritis Nodosa

Question 40

What vasculits presents with: conjunctivitis, dry sore mouth, polymorphic rash, red and swollen palms,

Answer 40

kawasakis

Question 41

What vasculits presents with: ENT symptoms (Epitaxisis, deafness), GN, neuropathy, pulmonary fibrosis

Answer 41

granulomatosis wth Polyangitis

Question 42

What vasculits presents with: rash, Late onset asthma, GN, peripheral neuropathy

Answer 42

eosiniophillic granulomatosis with polyangitis

Question 43

What vasculits presents with: Pulmonary fibrosis, GN, Rash, ENT symptoms, peripheral neuropathy,

Answer 43

Microscopic polyangitis

Question 44

What vasculitis presents predominantly in turkey, Japan and Iran

Answer 44

Behçets disease

Question 45

What vasculitis presents with genital ulcers, Eye lesions, skin lesions and Oral ulcers

Answer 45

Behçets disease