Rheumatology Flashcards
(14 cards)
What are the key skin features of dermatomyositis?
Gottron’s papules, Heliotrope rash, photosensitivity, macular rash and nail fold capillary dilatation
What are the causes of dermatomyositis?
Associated with a connective tissue disorder, idiopathic or underlying malignancy (ovarian, breast)
What is the cause of Marfan’s syndrome?
Mutation in fibrillin-1
What are the x-ray finding in psoriatic arthritis?
Pencil in cup - periarticular erosions and bone resorption.
What monitoring should be done when using hydroxychloroquine?
Eye checks - bull’s eye retinopathy may result in severe and permanent visual loss
What antibody is most associated with dermatomyositis?
Anti-Jo-1 antibody
What autoantibody is limited (central) systemic sclerosis associated with?
Anticentromere
What autoantibody is Diffuse cutaneous systemic sclerosis associated with?
Anti Scl-70 antibodies
What condition is cANCA associated with?
Granulomatosis with polyangiitis
What condition is pANCA associated with?
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)
What are radiological x-ray findings in Ankylosing Spondylitis?
What symptoms are associated with ANA-associated vasculitis?
Renal impairment, resp-haemoptysis & dyspnoea, systemic symptoms (fatigue, weight loss, fever), vasculitis rash
What types of vasculitis are associated with ANA?
Small vessel vasculitis
cANCA - granulomatosis with polyangiitis
pANCA - eosinophilic granulomatosis with polyangiitis + others
What antibody is associated with anti-phospholipid syndrome?
Lupus anticoagulant (LA) and anti-cardiolipin antibodies (aCL)
