RNA PT1

Question 1

This is the second smallest virus

Answer 1

Picornaviridae

Question 2

Viruses under picornaviridae

Answer 2

• enterovirus, hepatovirus, rhinovirus
• apathovirus (mouth-to-mouth disease)
• cardiovirus

Question 3

Agent of polio or poliomyelitis

Answer 3

Picornaviridae

Question 4

Most common serotype of picornaviridae

Answer 4

Enterovirus C serotype

Question 5

Four major polypeptides of picornaviridae

Answer 5

Vp1
Vp2
Vp3
Vp4

Question 6

These are the picornaviridae polypeptides that are major antibody binding sites

Answer 6

Vp1
Vp2
Vp3

Question 7

This is a picornaviridae polypeptide that is an internal protein

Answer 7

Vp4

Question 8

Picornaviridae viruses that infect humans and lower animals

Answer 8

Rhinovirus
Enterovirus

Question 9

Portal of entry in picornaviridae

Answer 9

Mouth

Question 10

Picornaviridae replicates in what part of thebody

Answer 10

Oropharynx
GIT

Question 11

Most virulent and common type of picornaviridae

Answer 11

Type 1

Question 12

Symptoms that affect the brain and spinal cord

Answer 12

Paresthesia
Meningitis
Paralysis

Question 13

Specimens for picornaviridae detection

Answer 13

Stool
Throat
Csf

Question 14

2 vaccine types

Answer 14

Inactivated poliovirus vaccine - Salk vaccine
Oral poliovirus vaccine - Sabin vaccine

Question 15

Largest enteroviral group

Answer 15

Coxsackie

Question 16

Mode of transmission of coxsackie

Answer 16

Ingestion

Question 17

Specimens for coxsackie detection

Answer 17

Stool
Blood
Throat

Question 18

Incubation period of coxsackie

Answer 18

2-9 days

Question 19

What group of coxsackie that causes flacid paralysis and what are the clinical manifestations

Answer 19

Group A COXSACKIE
- aseptic meningitis
- herpangina (infection in the mouth)
- hand foot mouth disease (common in children)

Question 20

Group of coxsackie that may cause more serious and fatal infections

Answer 20

Group B COXSACKIE

Question 21

Specimens used for detection in coxsackie

Answer 21

Throat washing
Stool
Nasal secretion

Question 22

This specimen can detect signs of meningitis in coxsackie

Answer 22

Csf

Question 23

Coxsackie: nucleic acid detection

Answer 23

Rt-pcr
Real-time PCR assay

Question 24

Screening tool for coxsackie

Answer 24

Serology

Question 25

Common cause of cold virus

Answer 25

Rhinovirus

Question 26

T/f: rhinovirus is acid stable

Answer 26

F

Question 27

Rhinovirus: Portal of entry

Answer 27

Respiratory tract

Question 28

Rhinovirus: Mode of transmission

Answer 28

Airborne droplets Fomites

Question 29

Epithelial cells of the nose

Answer 29

Tropism

Question 30

Receptor of rhinovirus

Answer 30

Intracellular adhesion protein molecule - 1

Question 31

This manifestation irritates your nasal lining, triggering extra mucus production

Answer 31

Sore throat

Question 32

This manifestation that causes inflammation in the eustachian tube

Answer 32

Otitis media

Question 33

This manifestation is build up by excessive mucus that causes the blockage of electrolyte channels

Answer 33

Cystic fibrosis

Question 34

Specimen used for detection in rhinovirus

Answer 34

Nasal secretion

Question 35

Tests to be done in diagnosing rhinosis

Answer 35

Rt-pcr Cell culture using plaque assay

Question 36

It has a wheel like appearance

Answer 36

Rotavirus

Question 37

From what family does rotavirus came from

Answer 37

Reoviridae

Question 38

Structural proteins of rotavirus

Answer 38

Vp1-4, vp6, vp7

Question 39

What group of rotavirus is the most important cause of endemic severe diarrheal disease in infants and young children worldwide

Answer 39

Group a

Question 40

What group of rotavirus causes outbreaks of diarrheal illness in adults and children in China and southeast asia

Answer 40

Group b

Question 41

What group of rotavirus that has sporadic cases and occasional outbreaks of diarrheal illness in children

Answer 41

Group c

Question 42

2 forms of rotavirus

Answer 42

Complete Incomplete

Question 43

Clinical manifestation of rotavirus

Answer 43

Diarrheal illness Fever Abdominal pain Vomiting

Question 44

Specimen in rotavirus

Answer 44

Stool

Question 45

Screening tool for rotavirus

Answer 45

PCR Elisa