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MYCOVIRO Final > RNA VIRUSES > Flashcards

RNA VIRUSES Flashcards

1
Q

T/F
Arenaviridae can be transmitted by arthropods

A

FALSE
RODENTS only

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2
Q

T/F
Bunyaviridae can be transmitted by rodents (arbovirus)

A

FALSE
RODENTS or ARTHROPODS

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3
Q

In Arenaviridae, LCM virus (LCMV), Lassa fever virus, Machupo Virus, Junin virus, Sabia virus disease

A

Lymphocytic choriomeningitis

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4
Q

Bunyaviridae viruses

A

LaCrosse virus, hantavirus, Rift Valley fever virus, Crimean Congo hemorrhagic fever virus

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5
Q

encephalitis

A

Arboviruses

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6
Q

pneumonia or hemorrhagic fevers

A

Hantaviruses

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7
Q

Hemorrhagic Fever w/ Renal syndrome (HFRS)

A

Hantavirus

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8
Q

nephropathia epidemica

A

Pumala hantavirus

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9
Q

Hantavirus

A

Sin Nombre virus

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10
Q

Caliciviridae
Virus:
Disease:

A

Norwalk virus, Sappovirus
Outbreaks of gastroenteritis among children and adults

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10
Q

Coronaviridae
Virus:
Disease:

A

SARS-CoV 1&2, MERS-CoV
Respiratory diseases; possible gastroenteritis

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11
Q

Filoviridae
Virus:
Disease:

A

Ebola virus, Marburg virus
Most pathogenic of the hemorrhagic fevers

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12
Q

Flaviviridae
Viruses:

A

Dengue Virus
Yellow Fever Virus
West Nile Virus St. Louis encephalitis virus, Hepatitis C

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13
Q

Flaviviridae
Dengue virus disease

A

Dengue fever (breakbone fever), dengue hemorrhagic fever

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14
Q

Flaviviridae
Yellow Fever virus disease

A

Acute viral haemorrhagic disease; can cause fever to severe liver disease

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15
Q

T/F
Flaviviridae are Arboviruses that is transmitted via vector

A

TRUE

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16
Q

Hepeviridae
Virus:
Disease:

A

Hepatitis E
Waterborne; similar to Hepatitis A but high fatality case amongst pregnant women

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17
Q

Orthomyxoviridae
Virus:
Disease:

A

Influenza A and B
Flu (malaise, headache, myalgia, cough)

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18
Q

Orthomyxoviridae Surface glycoproteins:

A

Hemagglutinin (HA)
Neuraminidase (NA)

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19
Q
  • rod-shaped spikes which attaches to sialic acid
  • 16 HA antigens
A

Hemagglutinin (HA)

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20
Q
  • mushroom-shaped spikes which releases mature virions from infected host cells
  • 9 NA antigens
A

Neuraminidase (NA)

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21
Q
  • major genetic changes resulting to novel viral antigens; only Influenza A
  • Reason why we have pandemic/ epidemic
A

Antigenic shift

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22
Q

Antigenic shift: H1N1

A

Spanish flu

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23
Q

Antigenic shift: H2N2

A

Asian flu

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24
Q

Antigenic shift: H3N2

A

Hongkong flu

25
Q

Antigenic shift: H5N1

A

Asian Avian flu (Highly pathogenic Avian Influenza)

26
Q

Antigenic shift: H7N9

A

Asian (first reported in China)

27
Q
  • minor genetic changes that occur infrequently; occurs in all Influenza types (A,B,C)
  • Reason why we have annual vaccination
A

Antigen drift

28
Q

Paramyxoviridae viruses

A

Rubeola/Measles
Rubula/Mump’s
Parainfluenza Virus
Respiratory Syncytial virus

29
Q
  • Measles – Koplik’s spots in oral mucosa
  • Subacute sclerosing panencephalitis
A

Rubeola/Measles

30
Q
  • Parotitis (swelling of the salivary glands)
  • Complication: orchitis (inflammation of testicles)
A

Rubula/Mump’s

31
Q
  • PIV-1: croup (laryngotracheobronchitis)
  • PIV-3: bronchiolitis & pneumonia
A

Parainfluenza Virus

32
Q

Most significant cause of acute lower respiratory tract infection in children<5 y.o.

A

Respiratory Syncytial virus

33
Q

Picornaviridae viruses

A

Enteroviruses
Rhinovirus

34
Q

Enteroviruses

A

Poliovirus,
Coxsackie A
Coxsackie B,
Echovirus

35
Q

T/F
Enteroviruses is an acid-sensitive
Rhinovirus is an acid resistant

A

FALSE
Enteroviruses is an acid-RESISTANT
Rhinovirus is an acid SENSTITIVE

36
Q

Major cause of common cold

A

Rhinovirus

37
Q

Acute, flaccid paralysis

A

Polio virus

38
Q

Retroviridae viruses

A

HIV-1
HIV-2
Human T-Lymphotropic Virus (HTLV-1 & 2)

39
Q
  • Responsible for the AIDS pandemic
  • Higher transmission rate
A

HIV-1

40
Q
  • Most common in West Africa
A

HIV-2

41
Q

Isolated in patients with Hairy Cell Leukemia

A

Human T-Lymphotropic Virus (HTLV-1 & 2)

42
Q

Rhabdoviridae
Virus:
Disease:

A

Rabies Virus
Rabies (Negri bodies – eosinophilic cytoplasmic inclusions in brain tissue)

43
Q

Togaviridae viruses

A

Rubivirus/Rubella
Alphavirus

44
Q

German measles/ Three-Day Measles – mild exanthematous disease

A

Rubivirus/Rubella

45
Q
  • Eastern, Western, Venezuelan equine encephalitis
  • Humans are dead-end hosts
A

Alphavirus

46
Q

Picornaviridae
Hepatitis Virus:
MOT:

A

Hepa A
Fecal-oral

47
Q

Hepadnaviridae
Hepatitis Virus:
MOT:

A

Hepa B
Sexual/ Parenteral (needle)/ Perinatal

48
Q

Flaviviridae
Hepatitis Virus:
MOT:

A

Hepa C
Sexual/ Parenteral (needle)/ Perinatal

49
Q

Delta virus
Hepatitis Virus:
MOT:

A

Hepa D
Sexual/ Parenteral (needle)/ Perinatal

50
Q

Hepeviridae
Hepatitis Virus:
MOT:

A

Hepa E
Fecal-oral

51
Q

Hepatitis virus that is the only DNA virus

A

Hepa B

52
Q

Hepatitis virus that can progress through chronic state

A

Hepa B, C, D

53
Q

Complications of Hepatitis A Virus
___ risk of fulminant liver disease

A

Low

54
Q

Complications of Hepatitis B Virus
_____% develop chronic infection, with ____ risk for liver cirrhosis and liver cancer

A

10-90
HIGH

55
Q

Complications of Hepatitis C Virus
____ develop chronic infection, with ___ risk for liver cirrhosis and liver cancer

A

85%
HIGH

56
Q

Complications of Hepatitis D Virus
____ risk for fulminant hepatitis, liver cirrhosis and liver cancer

A

HIGH

57
Q

Complications of Hepatitis E Virus
Fulminant liver failure in ____

A

pregnant women

58
Q

Childhood Diseases Exhibiting Exanthema (MGSCER)

A
  • Measles
  • German measles
  • Scarlet fever
  • Chicken pox
  • 5th disease (Erythema infectiosum)
  • 6th disease (Roseola)
59
Q

Viral Gastroenteritis that is a major cause in infants and child

A

Rotavirus

60
Q

Viral Gastroenteritis that is seen in infants and young adults

A

Adenovirus

61
Q

Viral Gastroenteritis that is most common cause of infectious gastroenteritis in the United States

A

Norovirus “winter vomiting bug”

MYCOVIRO Final (15 decks)

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