RNA VIRUSES Flashcards

(62 cards)

1
Q

T/F
Arenaviridae can be transmitted by arthropods

A

FALSE
RODENTS only

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2
Q

T/F
Bunyaviridae can be transmitted by rodents (arbovirus)

A

FALSE
RODENTS or ARTHROPODS

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3
Q

In Arenaviridae, LCM virus (LCMV), Lassa fever virus, Machupo Virus, Junin virus, Sabia virus disease

A

Lymphocytic choriomeningitis

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4
Q

Bunyaviridae viruses

A

LaCrosse virus, hantavirus, Rift Valley fever virus, Crimean Congo hemorrhagic fever virus

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5
Q

encephalitis

A

Arboviruses

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6
Q

pneumonia or hemorrhagic fevers

A

Hantaviruses

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7
Q

Hemorrhagic Fever w/ Renal syndrome (HFRS)

A

Hantavirus

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8
Q

nephropathia epidemica

A

Pumala hantavirus

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9
Q

Hantavirus

A

Sin Nombre virus

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10
Q

Caliciviridae
Virus:
Disease:

A

Norwalk virus, Sappovirus
Outbreaks of gastroenteritis among children and adults

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10
Q

Coronaviridae
Virus:
Disease:

A

SARS-CoV 1&2, MERS-CoV
Respiratory diseases; possible gastroenteritis

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11
Q

Filoviridae
Virus:
Disease:

A

Ebola virus, Marburg virus
Most pathogenic of the hemorrhagic fevers

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12
Q

Flaviviridae
Viruses:

A

Dengue Virus
Yellow Fever Virus
West Nile Virus St. Louis encephalitis virus, Hepatitis C

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13
Q

Flaviviridae
Dengue virus disease

A

Dengue fever (breakbone fever), dengue hemorrhagic fever

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14
Q

Flaviviridae
Yellow Fever virus disease

A

Acute viral haemorrhagic disease; can cause fever to severe liver disease

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15
Q

T/F
Flaviviridae are Arboviruses that is transmitted via vector

A

TRUE

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16
Q

Hepeviridae
Virus:
Disease:

A

Hepatitis E
Waterborne; similar to Hepatitis A but high fatality case amongst pregnant women

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17
Q

Orthomyxoviridae
Virus:
Disease:

A

Influenza A and B
Flu (malaise, headache, myalgia, cough)

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18
Q

Orthomyxoviridae Surface glycoproteins:

A

Hemagglutinin (HA)
Neuraminidase (NA)

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19
Q
  • rod-shaped spikes which attaches to sialic acid
  • 16 HA antigens
A

Hemagglutinin (HA)

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20
Q
  • mushroom-shaped spikes which releases mature virions from infected host cells
  • 9 NA antigens
A

Neuraminidase (NA)

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21
Q
  • major genetic changes resulting to novel viral antigens; only Influenza A
  • Reason why we have pandemic/ epidemic
A

Antigenic shift

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22
Q

Antigenic shift: H1N1

A

Spanish flu

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23
Q

Antigenic shift: H2N2

A

Asian flu

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24
Antigenic shift: H3N2
Hongkong flu
25
Antigenic shift: H5N1
Asian Avian flu (Highly pathogenic Avian Influenza)
26
Antigenic shift: H7N9
Asian (first reported in China)
27
- minor genetic changes that occur infrequently; occurs in all Influenza types (A,B,C) - Reason why we have annual vaccination
Antigen drift
28
Paramyxoviridae viruses
Rubeola/Measles Rubula/Mump’s Parainfluenza Virus Respiratory Syncytial virus
29
- Measles – Koplik's spots in oral mucosa - Subacute sclerosing panencephalitis
Rubeola/Measles
30
- Parotitis (swelling of the salivary glands) - Complication: orchitis (inflammation of testicles)
Rubula/Mump’s
31
- PIV-1: croup (laryngotracheobronchitis) - PIV-3: bronchiolitis & pneumonia
Parainfluenza Virus
32
Most significant cause of acute lower respiratory tract infection in children<5 y.o.
Respiratory Syncytial virus
33
Picornaviridae viruses
Enteroviruses Rhinovirus
34
Enteroviruses
Poliovirus, Coxsackie A Coxsackie B, Echovirus
35
T/F Enteroviruses is an acid-sensitive Rhinovirus is an acid resistant
FALSE Enteroviruses is an acid-RESISTANT Rhinovirus is an acid SENSTITIVE
36
Major cause of common cold
Rhinovirus
37
Acute, flaccid paralysis
Polio virus
38
Retroviridae viruses
HIV-1 HIV-2 Human T-Lymphotropic Virus (HTLV-1 & 2)
39
- Responsible for the AIDS pandemic - Higher transmission rate
HIV-1
40
- Most common in West Africa
HIV-2
41
Isolated in patients with Hairy Cell Leukemia
Human T-Lymphotropic Virus (HTLV-1 & 2)
42
Rhabdoviridae Virus: Disease:
Rabies Virus Rabies (Negri bodies – eosinophilic cytoplasmic inclusions in brain tissue)
43
Togaviridae viruses
Rubivirus/Rubella Alphavirus
44
German measles/ Three-Day Measles – mild exanthematous disease
Rubivirus/Rubella
45
- Eastern, Western, Venezuelan equine encephalitis - Humans are dead-end hosts
Alphavirus
46
Picornaviridae Hepatitis Virus: MOT:
Hepa A Fecal-oral
47
Hepadnaviridae Hepatitis Virus: MOT:
Hepa B Sexual/ Parenteral (needle)/ Perinatal
48
Flaviviridae Hepatitis Virus: MOT:
Hepa C Sexual/ Parenteral (needle)/ Perinatal
49
Delta virus Hepatitis Virus: MOT:
Hepa D Sexual/ Parenteral (needle)/ Perinatal
50
Hepeviridae Hepatitis Virus: MOT:
Hepa E Fecal-oral
51
Hepatitis virus that is the only DNA virus
Hepa B
52
Hepatitis virus that can progress through chronic state
Hepa B, C, D
53
Complications of Hepatitis A Virus ___ risk of fulminant liver disease
Low
54
Complications of Hepatitis B Virus _____% develop chronic infection, with ____ risk for liver cirrhosis and liver cancer
10-90 HIGH
55
Complications of Hepatitis C Virus ____ develop chronic infection, with ___ risk for liver cirrhosis and liver cancer
85% HIGH
56
Complications of Hepatitis D Virus ____ risk for fulminant hepatitis, liver cirrhosis and liver cancer
HIGH
57
Complications of Hepatitis E Virus Fulminant liver failure in ____
pregnant women
58
Childhood Diseases Exhibiting Exanthema (MGSCER)
- Measles - German measles - Scarlet fever - Chicken pox - 5th disease (Erythema infectiosum) - 6th disease (Roseola)
59
Viral Gastroenteritis that is a major cause in infants and child
Rotavirus
60
Viral Gastroenteritis that is seen in infants and young adults
Adenovirus
61
Viral Gastroenteritis that is most common cause of infectious gastroenteritis in the United States
Norovirus “winter vomiting bug”