Rush Hemostasis Flashcards
(30 cards)
inv formation of theombus at the site if vessel injury
hemostasis
occurs immediately to reduce blood flow at injury aite
arteriolar vasoconstriction
mediator of the arteriolar vasoconstriction thingy
reflex neurogenic mechanisms (RNM)
endothelin
formation of the immature platelet plug, and whats the term for it?
primary hemostasis; primary hemostatic plug
sequence of primary hemostasis
p adhesion
shape change
granule release
recruitment
aggregation
ASGRG
“ass gurg”
this is how strong the plug is during prime hemo
pretty weak platelet plug
consolidation of the immature plug?
secondary hemostasis
the sequence of second hemo
tissude factor exposure
coag cascade
fibrin form
plateleg aggregation
TCFP
term for contraction inti a solid permanent plug
stabilization
term for counterregulatory mehcanism to orevent too much clotting wnd eventual dissolution
resorption
inactivates factor 5 and 7 and its activated by what?
protein c, activated by thrombin bound to thrombomodulin
where is thrombin bound to thrombomodulin found
endothelial cell membrane protein
cofactor if peoteins c
protein s
what does antithrombin inhibit?
thrombin
kallikrein
7, 9, 10, 11, 12a (all are a)
what dors tissue factor pathway inhibitor inhibit?
7a and 10a
main factor for fibrin degeneration
plasmin
actuvates plasminogen to plasmin
tissue plasminogen activator (TPA)
the venn diagram that has venous endothelial and hypercoagulability
virchows triad
what does those triad mean in virchows triad
venous stasis (slow flow)
endothelial injury (damage)
hypercoagulability (clotting)
this can occur anywheere in cardiovascular sysetm
site of thrombosis
composition of thrombosis
platelets
fibrin
rbc
inflamm cells
this is laminated appearance due to akternating pale platelets and fibrin deposits and datker rbc layers
lines of zahn
where is lines of zahn seen, and it signifies thrombus formed via flowing blood
antemortem thrombus
arterial thrombosis:
site
propagation
composition
commin sites
turbulence or endothelial injury site
retrograde propagation
more platelets less rbc composition
coronary > cerebral > femoral