Rush Hemostasis Flashcards

(30 cards)

1
Q

inv formation of theombus at the site if vessel injury

A

hemostasis

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2
Q

occurs immediately to reduce blood flow at injury aite

A

arteriolar vasoconstriction

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3
Q

mediator of the arteriolar vasoconstriction thingy

A

reflex neurogenic mechanisms (RNM)
endothelin

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4
Q

formation of the immature platelet plug, and whats the term for it?

A

primary hemostasis; primary hemostatic plug

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5
Q

sequence of primary hemostasis

A

p adhesion
shape change
granule release
recruitment
aggregation

ASGRG

“ass gurg”

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6
Q

this is how strong the plug is during prime hemo

A

pretty weak platelet plug

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7
Q

consolidation of the immature plug?

A

secondary hemostasis

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8
Q

the sequence of second hemo

A

tissude factor exposure
coag cascade
fibrin form
plateleg aggregation

TCFP

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9
Q

term for contraction inti a solid permanent plug

A

stabilization

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10
Q

term for counterregulatory mehcanism to orevent too much clotting wnd eventual dissolution

A

resorption

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11
Q

inactivates factor 5 and 7 and its activated by what?

A

protein c, activated by thrombin bound to thrombomodulin

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12
Q

where is thrombin bound to thrombomodulin found

A

endothelial cell membrane protein

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13
Q

cofactor if peoteins c

A

protein s

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14
Q

what does antithrombin inhibit?

A

thrombin
kallikrein
7, 9, 10, 11, 12a (all are a)

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15
Q

what dors tissue factor pathway inhibitor inhibit?

A

7a and 10a

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16
Q

main factor for fibrin degeneration

17
Q

actuvates plasminogen to plasmin

A

tissue plasminogen activator (TPA)

18
Q

the venn diagram that has venous endothelial and hypercoagulability

A

virchows triad

19
Q

what does those triad mean in virchows triad

A

venous stasis (slow flow)
endothelial injury (damage)
hypercoagulability (clotting)

20
Q

this can occur anywheere in cardiovascular sysetm

A

site of thrombosis

21
Q

composition of thrombosis

A

platelets
fibrin
rbc
inflamm cells

22
Q

this is laminated appearance due to akternating pale platelets and fibrin deposits and datker rbc layers

A

lines of zahn

23
Q

where is lines of zahn seen, and it signifies thrombus formed via flowing blood

A

antemortem thrombus

24
Q

arterial thrombosis:
site
propagation
composition
commin sites

A

turbulence or endothelial injury site
retrograde propagation
more platelets less rbc composition
coronary > cerebral > femoral

25
venous thrombosis: site propagation compositiin common sites
stasis so slow blood sites anterograde propagation more rbc than platelets superficial leg and deep leg veins
26
term used for superficial leg veins and venous thrombosis
saphenous veins in varicose veins
27
sites of deep leg veins involved in venous thrombosis
popliteal femoral illiac
28
postmortem thrombosis usually have this characteristic thing
chicken fat clot *** currant jelly clot
29
this is thrombosis in heart chambers or aortic lumen
mural thrombi
30
thrombosis due to thrombi heart valves
vegetations