Salivary gland infections

Question 1

Common name for epidemic parotisis/sialadenitis

Answer 1

Mumps

Question 2

Enveloped, negative sense, ssRNA virus in the Paramyxoviridae family

Answer 2

Mumps virus

Question 3

The two glycoprotein spikes on mumps envelope

Answer 3

HN
F

Question 4

Function of HN on mumps virus

Answer 4

Hemagglutinin and neuraminidase used for binding

Question 5

Function of F protein on mumps virus

Answer 5

Fusion protein that promotes entry and cell-to-cell fusion

Question 6

Where primary replication of the mumps virus occurs

Answer 6

Nares and upper respiratory tract

Question 7

Target tissues of disseminated mumps viremia

Answer 7

Salivary/parotid glands
CNS
Testes/ovaries
Pancreas
Kidneys

Question 8

Systemic viral disease that causing lytic infection of cells, including desquamation of necrotic epithelial cells lining the salivary duct

Answer 8

Mumps virus

Question 9

Possible complications of mumps infection

Answer 9

Sterility
Type 1 DM
Deafness
Thyroiditis
Pneumonia
Meningoencepahlitis

Question 10

Serology tests for diagnosis of mumps infection

Answer 10

IgM titer
Hemagglutination inhibition test
Complement fixation test

Question 11

Molecular method for diagnosis of mumps infection

Answer 11

RT-PCR –> very sensitive

Question 12

Mumps vaccine type

Answer 12

Live attenuated
Trivalent (MMR)

Question 13

Most common cause of acute bacterial suppurative parotitis

Answer 13

S aureus

Question 14

Occurs due to retrograde seeding of Stenson’s duct by mixed flora in salivary stasis

Answer 14

Acute bacterial suppurative parotitis

Question 15

Pt presents with sudden onset of firm erythematous swelling in the preauricular area, over the parotid gland. The swelling is painful and tender to touch.

Answer 15

Acute bacterial suppurative parotitis

Question 16

Risk factors of acute bacterial suppurative parotitis

Answer 16

Poor oral hygiene
Dehydration
Debilitation
Intubation in elderly