Stomach infections

Question 1

Flagellated, gram negative, spiral bacilli. Oxidase and urease positive. Macroaerophilic and capnophilic.

Answer 1

H pylori

Question 2

Virulence factor of H pylori that neutralizes acid

Answer 2

Urease

Question 3

Virulence factor of H pylori that resists peristalsis

Answer 3

Adhesin

Question 4

Virulence factors of H pylori that cause gastric mucosal injury

Answer 4

Vacuolating cytotoxin A
Mucinase
Protease
Lipase

Question 5

Possible effects of H pylori infection

Answer 5

Chronic gastritis
PUD
Duodenal ulcer
Gastric adenocarcinoma
MALT lymphoma

Question 6

Metabolic abnormalities seen with recurrent vomiting

Answer 6

Hypochlorhydria and metabolic acidosis

Question 7

Common location of peptic ulcers in H pylori infection

Answer 7

Junction between corpus and antrum

Question 8

Normal gastric mucosa is replaced with fibrosis and proliferation of the epithelium

Answer 8

Gastric adenocarcinoma

Question 9

Serology for H pylori

Answer 9

IgG antibodies

Question 10

Test on biopsy for H pylori

Answer 10

Urease colorimetric test

Question 11

Culture mediums for H pylori

Answer 11

Campy
Skirrow’s

Question 12

Treatment for H pylori

Answer 12

PAMC

PPI
Amoxicillin
Metronidazole
Clarithromycin