SAS 10 Flashcards

1
Q

Have a nucleus 4 fused cyclic rings

Tetracyclines
Aminoglycosides
Macrolide
Lincomycins

A

Tetracyclines

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2
Q

Most popular antibiotic of tetracycline

Rolitetracycline
Demeclocycline
Oxytetracycline
Tetracycline

A

Tetracycline

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3
Q

Treats acne vaginalis

Tetracycline
Oxytetracycline
Demeclocycline
Rolitetracycline

A

Tetracycline

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4
Q

Made by condensing tetracycline w pyrrolidine & formaldehyde in the presence of tert-butyl alcohol.

Rolitetracycline
Demeclocycline
Oxytetracycline
Tetracycline

A

Rolitetracycline

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5
Q

From Streptomyces aureofaciens

Chlortetracycline HCL
Demeclocycline
Oxytetracycline
Methacycline

A

Chlortetracycline HCL

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6
Q

From mutated Streptomyces aureufaciens

Chlortetracycline HCL
Demeclocycline
Oxytetracycline
Methacycline

A

Demeclocycline

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7
Q

Most potent tetracycline

Minocycline HCL
Glycylcyclines
Doxycycline
Methacycline HCL

A

Minocycline HCL

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8
Q

IS IT TRUE OR FALSE: Aminoglycosides contains 3 rings that has either amino acid and sugar molecules

A

TRUE

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9
Q

which sugar molecules can contain amino substituent

A

Hexose

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10
Q

what are anti-bacterial that binds to 30s subunits?

A

Aminoglycosides
Tetracyclines

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11
Q

From streptomyces griseus

Streptomyces HCL
Streptomyces sulfate

A

Streptomyces sulfate

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12
Q

Agent of choice for treatment of certain occupational bacterial infections

Neomycin sulfate
Kanamycin sulfate
Gentamicin sulfate
Streptomyces sulfate

A

Streptomyces sulfate

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13
Q

From Streptomyces kanamycincetus

Neomycin sulfate
Kanamycin sulfate
Gentamicin sulfate
Streptomyces sulfate

A

Kanamycin sulfate

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14
Q

Semisynthetic derivative of Kanamycin A

A

Amikacin

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15
Q

From micromonospora purpurea

Neomycin sulfate
Kanamycin sulfate
Gentamicin sulfate
Streptomyces sulfate

A

Gentamicin sulfate

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16
Q

micin is from

A

Micromonospora

17
Q

From Streptomyces tenebrarius

Neomycin sulfate
Kanamycin sulfate
Tobramycin sulfate
Streptomyces sulfate

A

Tobramycin sulfate

18
Q

From spectinomycin spectabilis

Neomycin sulfate
Kanamycin sulfate
Tobramycin sulfate
Streptomyces sulfate
Streptomyces HCL

A

Streptomyces HCL

19
Q

Streptomyces fradiae
Streptomyces sepctabilis

partner up:
Streptomyces HCL
Streptomyces sulfate

A

Streptomyces fradiae - Streptomyces sulfate
Streptomyces spectabilis - Streptomyces HCL

20
Q

What are the tetracyclines that shows the least in vitro calcium binding?

A

MOD
(M) inocycline
(O) xytetracycline
(D) oxycycline

21
Q

From Streptomyces Erythraeus

Erythromycin
Clarithromycin
Azithromycin
Troleandomycin

A

Erythromycin

22
Q

Prototype of azalides, the nitrogen-containing 15-membered ring of macrolides.

Erythromycin
Clarithromycin
Azithromycin
Troleandomycin

A

Azithromycin

23
Q

The most potent inhibitor of CYP 450 enzymes of the commercially available macrolides.

Erythromycin
Clarithromycin
Azithromycin
Troleandomycin

A

Troleandomycin

24
Q

One of the most potent agents available against some non-spore-forming anaerobic bacteria

Lincomycin HCL
Clindamycin HCL
Clindamycin phosphate

A

Clindamycin HCL

25
Inhibits cell synthesis Teicoplanin Bacitracin Vancomycin Gramicidin
Vancomycin
26
impairs cell wall synthesis Teicoplanin Bacitracin Vancomycin Gramicidin
Teicoplanin
27
Acts as ionophore in bacterial cell Teicoplanin Bacitracin Vancomycin Gramicidin
Gramicidin
28
Prodrug of chloramphenicol intended for pediatric use Chloramphenicol palmitate Chloramphenicol sodium succinate
Chloramphenilcol palmitate
29
From pseudomonas fluorescens
Mupirocin
30
Classified as ketolide
Telithromycin
31
From Streptomyces Fradiae
Neomycin sulfate
32
Used in abdominal surgery to control bacterial flora
Neomycin sulfate