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PHA 069_MANUFACTURING > SAS 6 > Flashcards

SAS 6 Flashcards

1
Q

What are the uses of Semi-solids?

A
  • Vehicle for topically applied drugs
  • Emollient
  • Protective of occlusive dressing on the skin
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2
Q

this is widely used substance in semisolids besides water

A

Petrolatum and mineral oil

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3
Q

is a complex mixture of semisolids containing hydrocarbon aliphatic, cycle, saturated, unsaturated branch, and unbranched substances in varying proportions

A

Hydrocarbons

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4
Q

is obtained from petroleum acid and is preferred for those that have lower viscosity.

A

Mineral oil

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5
Q

is employed to increase the viscosity of mineral oil to prevent separation from an ointment

A

Hydrocarbon wax

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6
Q

are used in water removable creams as an emulsifier to develop a certain consistency in the cream

A

Stearic acid

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7
Q

are used in creams as AUXILLIARY emulsifiers and emollients.

A

Stearyl alcohol and cetyl alcohol

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8
Q

is the most commonly used in ointment vehicles

A

Petrolatum

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8
Q

What are the recognized vehicles for semisolids?

A

Absorption bases
hydrocarbon bases
water-soluble bases
water-removable bases

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9
Q

An oil in water emulsion and that upon application and rubbing in the skin, it vanishes.

A

Water-removable bases

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10
Q

are hydrophilic mixtures formed by the addition of substance miscible with hydrocarbons and possessing polar groups such as SO4, sulfonate, carboxyl hydroxyl, or an ether linage

A

Absorption base

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11
Q

These are prepared from mixtures of high and low molecular weights of polyethylene glycol

A

Water-soluble base

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12
Q

Water soluble base with low molecular weight are _______, with moderately higher molecules are unctuous, and with high molecular weights are _______.

A

Water soluble base with low molecular weight are LIQUID , with moderately higher molecules are unctuous, and with high molecular weights are SOLID.

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13
Q

Water soluble bases are also known as

A

greaseless ointment bases

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14
Q

Anhydrous ointments are manufactured by the _______ _______.

A

fusion method

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15
Q

what are the three ways of mixing phases in emulsion?

A

Simultaneous blending of the phases
external
dispersed phases

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16
Q

This type of mixing phases is good for large batch operation

A

Simultaneous blending of the phases

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17
Q

This type of mixing phases is useful for emulsion system with a low dispersed phase

A

external

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18
Q

This type of mixing phase is useful for many emulsion system

A

dispersed phase

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19
Q

_________ may be used in ophthalmic preparation against bacterial or fungal contamination.

A

Boric acid

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20
Q

Provide 2 shapes in rectal suppository

A

Torpedo
bullet

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21
Q

Provide 3 shapes in vaginal suppository

A

Ovoid
Cone
Globular

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22
Q

Provide 1 shape in urethal

A

Pencil-like

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23
Q

synonym of vaginal suppositories

A

pessaries

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24
Q

synonym of urethral suppositories

A

bougies

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25
Q

SUPPOSITORY: relieves nausea and vomiting and as tranquilizer

A

Chlorpromazine and Prochlorperazine

26
Q

SUPPOSITORY: opioid analgesia

A

Morphine and Oxymorphone

27
Q

SUPPOSITORY: relieves migraine

A

Ergotamine tartrate

28
Q

SUPPOSITORY: NSAID and antipyretic

A

Indomethacin

29
Q

SUPPOSITORY: relieves nausea and vomiting

A

Ondansetron

30
Q

Most frequently employed as suppository base

A

Fatty bases

31
Q

Most common base for rectal suppository

A

Cocoa butter

32
Q

SUPPOSITORY FATTY BASE: Made from triglycerides from palm, palm kernel, and coconut oils.

A

Fattibase

33
Q

SUPPOSITORY FATTY BASE: From Triglycerides from COCONUT OIL

A

Wecobee

34
Q

SUPPOSITORY FATTY BASE: From SATURATED FATTY ACIDS

A

Witepsol

35
Q

Most frequently use suppository base for vaginal insertion

A

Glycerinated gelatin

36
Q

The simples and oldest method of preparing suppository

A

Hand molding

37
Q

a preparation of suppository that results in a more elegant appearance than hand molding

A

Compression molding

38
Q

The most commonly used method in producing suppositories both in small and large scale.

A

Pour molding

39
Q

An automated method for molding suppositories that is directly to their wrapping material

A

In-package molding

40
Q

SUPPOSITORY TEST: Measures liquefaction time of rectal suppositories in apparatus that stimulates in vivo condition.

A

Liquefaction

41
Q

SUPPOSITORY TEST: Designed as a method for measuring the fragility or brittleness of suppositories

A

Breaking test

42
Q

SUPPOSITORY TEST: Testing the rate of in vitro release of drug substances from suppository

A

Dissolution test

43
Q

are fever producing organic substances arising from microbial contamination

A

pyrogens

44
Q

Injection for asthma

A

Aminophylline

45
Q

Injection for stimulant in treating emergency cardiac and respiratory failure

A

Caffeine and Sodium benzoate

46
Q

Injection as local anesthetic

A

Procaine hydrochloride

47
Q

Injection for diabetes

A

Insulin

48
Q

What is type 1 glass container for parenterals

A

High resistant borosilicate glass

49
Q

what is type 2 glass container for parenterals

A

Treated soda lime glass

50
Q

what is type NP glass for parenterals

A

General purpose soda lime glass

51
Q

A type of parenteral glass preferred for parentals

A

Type 1: Highly resistant borosilicate glass

52
Q

A type of parenteral glass that is for buffered aqueous solution and for dry powders and oleaginous solution

A

TYPE 2: Treated soda lime glass

53
Q

A type of parenteral glass that is for dry powders and oleaginous solution

A

TYPE 3: Soda lime glass

54
Q

A type of parenteral glass that is for tablets,suspension, ointments,nd extractives

A

TYPE NF: General purpose soda lime glass

55
Q

These are used to seal opening of cartidges, vials and bottles providing a material soft and elastic enough to permit entry and withdrawal of hypodermic needle.

A

Rubber closures

56
Q

Provide 3 filter type for parenterals

A

Asbestos pad
Cellulose ester membrane
Sintered glass candles

57
Q

what is the principal material of asbestos pad

A

Asbestos fiber and wood cellulose

58
Q

what is the principal material of cellulose ester membrane

A

Cellulose nitrate, Cellulose acetate

59
Q

what is the principal material of diatomaceous earth

A

Diatoms(80%), Silicon dioxide, Iron (III) oxide, and other

60
Q

what is the principal material of sintered glass candles

A

Borosilicate glass

61
Q

what is type 3 glass for parenterals

A

Soda lime glass

62
Q

what is the principal material of glazed porcelain candles

A

Clay, silicon dioxide

PHA 069_MANUFACTURING (18 decks)

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