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PHA 069_MANUFACTURING > SAS 6 > Flashcards

SAS 6 Flashcards

(63 cards)

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1
Q

What are the uses of Semi-solids?

A
  • Vehicle for topically applied drugs
  • Emollient
  • Protective of occlusive dressing on the skin
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2
Q

this is widely used substance in semisolids besides water

A

Petrolatum and mineral oil

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3
Q

is a complex mixture of semisolids containing hydrocarbon aliphatic, cycle, saturated, unsaturated branch, and unbranched substances in varying proportions

A

Hydrocarbons

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4
Q

is obtained from petroleum acid and is preferred for those that have lower viscosity.

A

Mineral oil

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5
Q

is employed to increase the viscosity of mineral oil to prevent separation from an ointment

A

Hydrocarbon wax

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6
Q

are used in water removable creams as an emulsifier to develop a certain consistency in the cream

A

Stearic acid

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7
Q

are used in creams as AUXILLIARY emulsifiers and emollients.

A

Stearyl alcohol and cetyl alcohol

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8
Q

is the most commonly used in ointment vehicles

A

Petrolatum

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8
Q

What are the recognized vehicles for semisolids?

A

Absorption bases
hydrocarbon bases
water-soluble bases
water-removable bases

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9
Q

An oil in water emulsion and that upon application and rubbing in the skin, it vanishes.

A

Water-removable bases

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10
Q

are hydrophilic mixtures formed by the addition of substance miscible with hydrocarbons and possessing polar groups such as SO4, sulfonate, carboxyl hydroxyl, or an ether linage

A

Absorption base

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11
Q

These are prepared from mixtures of high and low molecular weights of polyethylene glycol

A

Water-soluble base

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12
Q

Water soluble base with low molecular weight are _______, with moderately higher molecules are unctuous, and with high molecular weights are _______.

A

Water soluble base with low molecular weight are LIQUID , with moderately higher molecules are unctuous, and with high molecular weights are SOLID.

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13
Q

Water soluble bases are also known as

A

greaseless ointment bases

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14
Q

Anhydrous ointments are manufactured by the _______ _______.

A

fusion method

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15
Q

what are the three ways of mixing phases in emulsion?

A

Simultaneous blending of the phases
external
dispersed phases

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16
Q

This type of mixing phases is good for large batch operation

A

Simultaneous blending of the phases

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17
Q

This type of mixing phases is useful for emulsion system with a low dispersed phase

A

external

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18
Q

This type of mixing phase is useful for many emulsion system

A

dispersed phase

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19
Q

_________ may be used in ophthalmic preparation against bacterial or fungal contamination.

A

Boric acid

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20
Q

Provide 2 shapes in rectal suppository

A

Torpedo
bullet

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21
Q

Provide 3 shapes in vaginal suppository

A

Ovoid
Cone
Globular

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22
Q

Provide 1 shape in urethal

A

Pencil-like

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23
Q

synonym of vaginal suppositories

A

pessaries

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24
synonym of urethral suppositories
bougies
25
SUPPOSITORY: relieves nausea and vomiting and as tranquilizer
Chlorpromazine and Prochlorperazine
26
SUPPOSITORY: opioid analgesia
Morphine and Oxymorphone
27
SUPPOSITORY: relieves migraine
Ergotamine tartrate
28
SUPPOSITORY: NSAID and antipyretic
Indomethacin
29
SUPPOSITORY: relieves nausea and vomiting
Ondansetron
30
Most frequently employed as suppository base
Fatty bases
31
Most common base for rectal suppository
Cocoa butter
32
SUPPOSITORY FATTY BASE: Made from triglycerides from palm, palm kernel, and coconut oils.
Fattibase
33
SUPPOSITORY FATTY BASE: From Triglycerides from COCONUT OIL
Wecobee
34
SUPPOSITORY FATTY BASE: From SATURATED FATTY ACIDS
Witepsol
35
Most frequently use suppository base for vaginal insertion
Glycerinated gelatin
36
The simples and oldest method of preparing suppository
Hand molding
37
a preparation of suppository that results in a more elegant appearance than hand molding
Compression molding
38
The most commonly used method in producing suppositories both in small and large scale.
Pour molding
39
An automated method for molding suppositories that is directly to their wrapping material
In-package molding
40
SUPPOSITORY TEST: Measures liquefaction time of rectal suppositories in apparatus that stimulates in vivo condition.
Liquefaction
41
SUPPOSITORY TEST: Designed as a method for measuring the fragility or brittleness of suppositories
Breaking test
42
SUPPOSITORY TEST: Testing the rate of in vitro release of drug substances from suppository
Dissolution test
43
are fever producing organic substances arising from microbial contamination
pyrogens
44
Injection for asthma
Aminophylline
45
Injection for stimulant in treating emergency cardiac and respiratory failure
Caffeine and Sodium benzoate
46
Injection as local anesthetic
Procaine hydrochloride
47
Injection for diabetes
Insulin
48
What is type 1 glass container for parenterals
High resistant borosilicate glass
49
what is type 2 glass container for parenterals
Treated soda lime glass
50
what is type NP glass for parenterals
General purpose soda lime glass
51
A type of parenteral glass preferred for parentals
Type 1: Highly resistant borosilicate glass
52
A type of parenteral glass that is for buffered aqueous solution and for dry powders and oleaginous solution
TYPE 2: Treated soda lime glass
53
A type of parenteral glass that is for dry powders and oleaginous solution
TYPE 3: Soda lime glass
54
A type of parenteral glass that is for tablets,suspension, ointments,nd extractives
TYPE NF: General purpose soda lime glass
55
These are used to seal opening of cartidges, vials and bottles providing a material soft and elastic enough to permit entry and withdrawal of hypodermic needle.
Rubber closures
56
Provide 3 filter type for parenterals
Asbestos pad Cellulose ester membrane Sintered glass candles
57
what is the principal material of asbestos pad
Asbestos fiber and wood cellulose
58
what is the principal material of cellulose ester membrane
Cellulose nitrate, Cellulose acetate
59
what is the principal material of diatomaceous earth
Diatoms(80%), Silicon dioxide, Iron (III) oxide, and other
60
what is the principal material of sintered glass candles
Borosilicate glass
61
what is type 3 glass for parenterals
Soda lime glass
62
what is the principal material of glazed porcelain candles
Clay, silicon dioxide

PHA 069_MANUFACTURING (18 decks)

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