SAS 6 COMPLETE

Question 1

What are the widely used substance in semisolids next to water?

Answer 1

Petrolatum and mineral oil

Question 2

is a complex mixture of semisolids containing hydrocarbon aliphatic, cycle, saturated, unsaturated branch and unbranched substances in varying proportions.

Answer 2

Petrolatum

Question 3

this is employed to increase the viscosity of mineral oil to prevent separation from the ointment

Answer 3

Hydrocarbon wax
example: paraffin and ceresin wax

Question 4

are used in water removable creams as an emulsifier to develop a certain consistency in the cream.

Answer 4

stearic acid

Question 5

are used in creams as auxiliary emulsifiers and emollients.

Answer 5

stearyl alcohol and cetyl alcohol

Question 6

what are the 4 classes of semi-solid vehicles

Answer 6

Hydrocarbon vehicle
Absorption vehicle
water removable vehicle
water soluble vehicle

Question 7

also known as greaseless ointment bases

Answer 7

water-soluble vehicle

Question 8

____________ is the most commonly used in ointment vehicles.

Answer 8

Petrolatum

Question 9

examples of absorption base

Answer 9

lanolin, cholesterol, sterols, sorbitan monostearate, monoolate

Question 10

between water removable and absorption base which is w/o and o/w

Answer 10

w/o is absorption base whereas, o/w is water removable

Question 11

anhydrous ointments are manufactured by this method.

Answer 11

Fusion method

Question 12

this rectal suppository is intended to relief nausea, vomiting, and as tranquilizer

Answer 12

Prochlorperazine and Chlorpromazine

Question 13

this rectal suppository is intended as opioid analgesia

Answer 13

morphine and oxymorphone

Question 14

this rectal suppository is intended for anti-inflammatory analgesic and analgesic and antipyretic

Answer 14

Indomethacin

Question 15

this rectal suppository relieves nausea and vomiting

Answer 15

Ondansetron

Question 16

the majority of the components melt at rectal temperature of _______.

Answer 16

36 celsius

Question 17

Most frequently employed suppository base

Answer 17

Oleaginous base

Question 17

Most common base used for rectal suppository

Answer 17

Cocoa butter

Question 18

Made from triglycerides from palm, palm kernel, and coconut oils with self-emulsifying glyceryl monostearate and polyoxyl stearate.

Answer 18

Fattibase

Question 19

From triglycerides derived from coconut oil

Answer 19

Wecobee

Question 20

From triglycerides of saturated fatty acid C12-C18

Answer 20

Witepsol

Question 21

Most frequently used in preparation of vaginal suppository

Answer 21

Glycerinated gelatin

Question 22

this base does not melt on body temperature but rather dissolve slowly in the body’s fluid.

Answer 22

Polyethyleme glycols

Question 23

also called macromelting range test

Answer 23

melting range test

Question 24

measures the liquefaction time of rectal suppositories in an apparatus that IN-VIVO condition

Answer 24

Liquefaction/softening time test

Question 25

the rate IN-VITRO release of drug substance from suppositories

Answer 25

Dissolution testing

Question 26

designed as a method for measuring the fragility or brittleness of suppository.

Answer 26

Breaking test

Question 27

are sterile, small, usually cylindrical-shaped solid objects 3.3mm in diameter and 8mm in length.

Answer 27

Pellets

Question 28

what is the most used vehicles for sterile product

Answer 28

water

Question 29

polyethylene glycol, propylene glycol, fixed oil, and benzyl benzoate are examples of...

Answer 29

Sterile: Non-aqueous solution:

Question 30

what type of glass is preferred for parenterals

Answer 30

Type I: Highly resistant borosilicate glass

Question 31

what type of glass is preferred for buffered aqueous solution and for dry powders and oleaginous solution

Answer 31

Type II: Treated soda lime glass

Question 32

what type of glass is preferred for dry powders and oleaginous solutions.

Answer 32

Type III: Soda lime glass

Question 33

what type of glass is preferred for tablets, oral solutions, suspensions, ointments, and extractives.

Answer 33

Type NF: General purpose soda lime glass