SAS 6 Flashcards

1
Q

Are physical and chemical reactions that occur in vitro between two or more drug when the solutions are combined in the same syringe, tubing, or bottle

A

Incompatibilities

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2
Q

This type of reaction can cause visible changes, including precipitation; changes in color, consistency, or oplescence; or gas production

A

Physical reactions

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3
Q

occurs more commonly with multiple additives.

A

Physical incompatibility

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4
Q

occurs when mixing two drugs and changes the potency of their active ingredients

A

Chemical incompatibility

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5
Q

Is a term used to describe the interaction of two of more substances that result in changes to the medical, physical, or chemical properties of the pharmaceutical dosage forms

A

Compatibility

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6
Q

ICU means..

A

Intensive care unit

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7
Q

is an undesirable reaction that occurs between the drug and the solution, container or another drug

A

Incompatibility

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8
Q

Means outside the living body and in an artificial environment such as test tube or petri dish

A

In-vitro

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9
Q

Means within a living organism such as plant or animal

A

In-vivo

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10
Q

A type of manifestion that happens between solids and liquids

A

Incomplete Solution: Insolubility

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11
Q

A type of manifestion that has the inability of the solid material to dissolve in a particular solvent system

A

Incomplete Solution: Insolubility

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12
Q

A type of manifestion that two or more liquids fail to mix homogenously

A

Incomplete Solution: Immiscibility

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13
Q

A type of manifestion that occurs due to solvent is insoluble when it is added to solution

A

Precipitation

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14
Q

A type of manifestion that results when highly hydrted inorganic ions deprive organic ions and molecules of adequate water molecules to remain dissolved

A

Precipitation: Salting-out a.k.a DEHYDRATION

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15
Q

A type of manifestion that electrolytes and Non-electrolytes compete for water molecules

A

Precipitation: Salting-out a.k.a DEHYDRATION

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16
Q

A type of manifestion that absorbs heat=increase temp of solution=increase solubility

A

Precipitation: Change in temperature: Endothermic reaction

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17
Q

A type of manifestion that gives off heat=decrease temp=decrease solubility of the solution

A

Precipitation: Change in temperature: Exothermic Reaction

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18
Q

A type of manifestion that absorbs moisture=liquefy

A

Liquefaction/Melting: Deliquescence

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19
Q

A type of manifestion that is due to lowering of MP of two olids combined together at room temperature

A

Liquefaction/Melting: Eutexia

20
Q

A type of manifestion that releases H2O of crystallization

A

Liquefaction/Melting: Efflorescence

21
Q

A type of manifestion that increases vapor pressure

A

Vaporization

22
Q

A type of manifestion that has the ability of a substance to exist in different crystalline forms

A

Polymorphism

23
Q

A type of manifestion that is a reverse of liquefaction

A

Water loss

24
Q

Type of incompatibility: Gum+alcohol

A

Insolubility

25
Q

Type of incompatibility: Oil+water

A

Immiscibility

26
Q

Type of incompatibility: Camphor+water+KBr

A

Salting-out

27
Q

Type of incompatibility: Ammonium chloride solution

A

Endothermic reaction

28
Q

Type of incompatibility: Crumbling of ointments

A

Water loss

29
Q

Type of occurence: Dehydrogenation

A

Oxidation

30
Q

Type of occurence: VILEORA

A

Oxidation

31
Q

Type of occurence: Hydrogenation

A

Reduction

32
Q

Type of occurence: VDGEROA

A

Reduction

33
Q

Type of occurence: Ca(OH)2 + CO2

A

Acid base reaction: Precipitation

34
Q

Type of occurence: Effervescent granules

A

Acid-base reaction: Evolution of gas

35
Q

Type of occurence: most common cause of degradation; eg. Ester, ASA, Amide

A

Hydrolysis

36
Q

Type of occurence: a.k.a Photooxidation, Photolysis

A

Photochemical Degradation

37
Q

Type of occurence: occurence of an optically active drug to an optically inactive drug

A

Racemization

38
Q

Type of occurence: Racemic mixture

A

Racemization

39
Q

Type of occurence: Formation of gels

A

Gelatinization

40
Q

Type of occurence: formation of cake

A

cementation

41
Q

Chemical can be changing the order of mixing the solutions in dilute forms, without or by changing the order of mixing

A

Tolerated incompatibility

42
Q

change in the formulation is needed with a compound having equal therapeutic value

A

Adjusted incompatibilities

43
Q

chemical reaction takes place, immediately after combining the prescription ingredients

A

Immediate incompatibility

44
Q

chemical reaction proceeds at a very slow rate and no appreciable visible change occurs which may develop on keeping the product for a long time

A

Delayed incompatibility

45
Q

When the prescriber knowingly prescribes the imcompatible drugs

A

Intentional

46
Q

When the prescriber prescribes the drugs without knowing that there is incompatibility between the prescribed drugs

A

Unidirectional