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Flashcards in Schistosomiasis -Hunter Deck (89)
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1

What is the risk of schistosomiasis (blood fluke)

1/6th of worlds pop

2

What are the major parasites that cause schistosomiasis?


Schistosoma mansoni; S. japonicum; S. haematobium

3

What are the minor parasites that cause schistosomias?

S. mekongi, S. intercalatum

4

S. manson and S. intercalatum is most commonly located in what country?

subsaharan Africa and western hemisphere of S. America

5

S. haematobium is limited to (blank) and is considered the (blank) schistosoma

Africa
urinary

6

S. Japoncium is found where?

china, philliapenes

7

Where do you find S. mekongi?

vietnam

8

Are the life cycles of the schistosomes similiar?

yes

9

Schistosoma is acquired through (blank)

wading through water

10

What is the life cycle of schistosomes?

cercariae enter skin-> migrate to lungs then liver-> then to mesentaric veins-> adults develop here -> males and females copulate and make eggs-> enter intestine-> passed in feces

11

Are schistoma mansoni eggs large?

yes

12

What is the female version of shistosomes and what does it need to survive

miracidia-> needs to be in a snail to survive

13

What am I talking about:
you need snails and a bad sewer system to have this pathogen survive

Schistosoma mansoni

14

The schistosoma egg cannot hatch until it hits (blank)

water

15

Adult schistomsome are (blank) to the immune system, the eggs are not

invisible

16

Since eggs of schistosomes have to erode its way through the blood vessel and into the bowel, eggs release (blank)

enzymes (this are crazy immunogenic)

17

In S. mansoni, what snail do you need for it to survive?

biomphalaria

18

In S. hematobium, what snail do you need for it to survive?

Bulinus

19

In S. Japonicum, what snail do you need for it to survive?

oncomelania

20

cercariae have a head that senses (blank)

amino acids

21

Use the names of schistosomes to describe life cycle:

cercariae- shistosomula- miracidia and cecariae

22

THe males shcistomsoma mansoni have 2 suckers that do what?

link them to the mesentaric veins.

23

How do the worms hide from the immune system?

worms have skin or tegument that allows them to acquire host moecules (such as RBC, glycotproeins and MHC molecules) (makes an antigenic disguise)

24

Cercarial penetration of skin can cause a transient (blank)

dermatitis

25

Migration of (Blank) through lungs can cause (blank) that can be severe in heavy infections

schistosomules
pneumonitis

26

What adult worms do you find in the superior mesentaric veins?

mansoni and japonicum

27

What adult worms do you find in the vesicle plexus of bladder?

hematobium (cause no clinical symptoms)

28

Onset of egg production causes (blank)

katayama fever (allergic response)

29

Intestinal or urinary bladder symptoms are due to eggs passing though tissue to lumen-> which can result in what?

severe hemorrhagic cystitis
gastroenteritis

30

Eggs swept up into portal circulation to liver cause (blank) and a (blank)

granulomas
T-cell mediated delayed hypersensitivity reaction to eggs