SEE 6 Flashcards

(37 cards)

1
Q

cleomyocin is toxic to the?

A

lungs

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2
Q

cisplatin is toxic to the ?

A

kidneys

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3
Q

doxorubicin is toxic to the ?

A

heart

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4
Q

cyclophophains is toxic to the ?

A

liver

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5
Q

streptozocin is toxic to the ?

A

liver

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6
Q

methotrexate is toxic to the?

A

liver

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7
Q

where do CCB’s work?

A

phase 2, plateau phase of ventricular action potential & phase 4 of the pacemaker action potential

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8
Q

what 3 things increase the likelihood of digitalis toxicity

A

hypokalemia, hypercalcemia, hypomagnesemia

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9
Q

top 5 causes of anaphylactic reactions =

A

NMB, latex, abx, colloids, hypnotics.

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10
Q

what is the universal recipient

A

AB

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11
Q

what factors does cryoprecipitate contain

A

I, VIII, XIII

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12
Q

whats the formula for ABL

A

EBV x (Hct - aHCT / HCT)

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13
Q

whats the 4-2-1 rule

A

4ml/kg first 10kg, 2ml/kg second 10kg, 1ml/kg remainder….. shortcut is add 40 to total kg if >20

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14
Q

too much LR causes what electrolyte disturbance

A

metabolic alkalosis

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15
Q

mannitol causes ___volemia, ____kalemia, ___natremia

A

hypovolemia, hyperkalemia, hyponatremia

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16
Q

virchows triangle -

A

endothelial injury, stasis or truant blood flow, hypercoagulability of blood

17
Q

hemophilia A = factor __ def

18
Q

hemophilia B = factor __ def

A

9 (christmas)

19
Q

what is the order of heat loss

A

radiation, convection, evaporation, conduction

20
Q

what are the 2 hormones of the posterior pit

A

adh and oxytocin

21
Q

which is more potent, T3 or T4?

A

T3 is 4x more potent

22
Q

T_ is converted to T_ in the tissues

23
Q

graves is ___ and hasimotos is ____

24
Q

thyroid storm occurs ___ posted

25
what are the cardiac effects of hypocalcemia
prolonged QT, dec myocardial contractility
26
what is the formula for anion gap
na - cl - hco3 normal is 9-15
27
ekg changes with hyperkalemnia
prolonged PR, widened QRS, peaked or tented T waves
28
ekg changes of hypokalemia
prolonged PR and QT, flattened T wave, prominent U wave
29
aldosterone causes sodium and water ___ and potassium and hydrogen ___
retention, excretion
30
addisons dz means you have ____ aldosterone
dec. so hyponatremia and hyperkalemia
31
cushings dz means you have
excessive cortisol. htn. hypokalemia, hyperglycemia. moon face, buff hump
32
conn's dz = primary _____ characterized by __Na and ___K
hyperaldosteronism, inc NA, dec K
33
what is the best indicator of renal status
creatinine clearance
34
whats the MOA Of diamox? hint it's a carbonic anhydrase inhibitor
inhibits carbonic anhydrase in proximal tubule which decreases Na reabsorption
35
___ your acids = alkalosis
puke
36
___ your bases = acidosis
poop
37
what is mendelsons
ph < 2.5, volume <25