Seizure Medications Flashcards

1
Q

What are side effects of Phenytoin?

A

Gingival hyperplasia, hirsutism, morbilliform (measle-like) rash, rickets, osteomalacia

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2
Q

Is phenytoin safe in pregnancy?

A

No, category D pregnancy risk.

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3
Q

What is the black box warning for valproic acid?

A

Fatal hepatic failure and pancreatitis. Common symptoms are n/v, anorexia, and abdominal pain. Neonates may have congenital malformations and decreased mental capacity.

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4
Q

What are side effects with valproic acid?

A

Hyperammonemia, rash, weight gain, hair loss, tremor, and blood dycrasias.

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5
Q

Does valproic acid have a pregnancy risk?

A

Category D pregnancy risk

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6
Q

What drug can cause hyperammonemia when combined with valproic acid?

A

Topamax

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7
Q

Which antiseizure medications cause hyponatremia?

A

Carbamazepine, oxcarbazepine, eslicarbazepine

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8
Q

What are adverse effects of topamax?

A

Metabolic acidosis, hyperthermia, rare cases of angle-closure glaucoma

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