Glossary

Question 1

A xanthine oxidase inhibitor. Currently the drug of choice in the treatment of chronic tophaceous gout. Reduces blood uric acid levels and prevents the formation of tophi.

Answer 1

Allopurinol

Question 2

A central acting drug to relieve spasticity. Acts within the spinal cord to suppress hyperactive reflexes involved in regulation of muscle movement.

Answer 2

Baclofen

Question 3

Baseline labs for all DMARDs

Answer 3

1. CBC with WBC diff
2. urine pregnancy test
3. ALT, AST
4. TB skin test if needed
5. serum creatinine

Question 4

Inhibit bone resorption by decreasing the activity of osteoclasts.

Answer 4

Bisphosphonates

Question 5

A COX-2 inhibitor indicated for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, acute pain, and dysmenorrhea.

Answer 5

Celecoxib (Celebrex)

Question 6

Antiinflammatory agent specific for gout

Answer 6

Colchicine

Question 7

A cholinesterase inhibitor used to slow the progression of cognitive and behavioral dysfunction in Alzheimer Disease.

Answer 7

donazepril (Aricept)

Question 8

Relieve symptoms of severe RA and may also delay disease progression.

Answer 8

Glucocorticoids in rheumatoid Arthritis

Question 9

A recombinant uric acid oxidase drug. It is an IV medications used for the treatment of chronic gout patients who have not responded to probenecid and allopurinol.

Answer 9

Pegloticase

Question 10

A uricosuric agent used to treat gout by increasing the excretion of uric acid. It also prevents the formation of tophi.

Answer 10

Probenecid

Question 11

A selective estrogen receptor modulator (SERM) that exerts estrogenic effects in some tissues and antiestrogenic effects in others. It is indicated for prevention and tx of osteoporosis in postmenopausal women and protection against estrogen receptor-positive breast cancer.

Answer 11

Raloxifene

Question 12

A non-benzodiazepine hypnotic melatonin agonist used in the treatment of insomnia

Answer 12

Ramelteon

Question 13

Side effects of SSRIs:

Answer 13

Sexual dysfunction, Weight gain, Serotonin syndrome

Question 14

What are the most common side effects of TCAs?

Answer 14

1. anticholinergic effects
2. sedation
3. orthostatic hypotension

Question 15

What two drug classes are considered first line in treating generalized anxiety disorder (GAD)?

Answer 15

SSRIs and SNRIs

Question 16

What are some of the contraindications for bupropion?

Answer 16

Seizure disorder, CNS tumor, head trauma, hypertension, tachycardia, weight loss

Question 17

Which class of medication is doxepin?

Answer 17

Tricyclic antidepressant

Question 18

What are two drugs developed for epilepsy, but can work for migraines?

Answer 18

divalproex (Depakote ER) and topiramate (Topamax)

Question 19

What is the name of a non-benzodiazepine drug used to treat depression?

Answer 19

Buspirone

Question 20

What are the three common mood-stabilizing drugs?

Answer 20

Lithium, Carbamazepine, and valproic acid

Question 21

Long-term oral glucocorticoid therapy can result in the adverse effect of:

Answer 21

osteoporosis

Question 22

Which class of medication is considered first line in terminating a migraine attack?

Answer 22

Serotonin Receptor Agonists (Triptans)