self study review

Question 1

High incidence antigens are:

Answer 1

Found in a majority of the population
Sometimes referred to as public genes

Question 2

Dosage is:

Answer 2

A stronger expression of a trait inherited in the homozygous state, as compared to being inherited in the heterozygous
state

Question 3

Which of the following are possible genotypes for an individual who is blood type B?
BO
BB
AB

Answer 3

BO
BB

Question 4

GMP systems include:

Answer 4

Reagent / equipment suppliers
Testing personnel and procedures
Storage systems
Customer reviews

Question 5

Which of the following organizations are federal agencies that are involved with laboratory inspection / accreditation?
The Joint Commission
CAP
FDA

Answer 5

The Joint Commission
CAP
FDA

Question 6

With what aspect(s) of the laboratory operation is OSHA concerned?

Answer 6

Safety in the workplace

Question 7

The purpose of Good Manufacturing Processes (GMPs) in the laboratory:

Answer 7

Ensure that testing is conducted in a controlled and auditable manner
Ensure that testing is accurate, consistent, and reliable

Question 8

If an SOP is changed, the laboratory must:

Answer 8

Document the date of, and reason for, the change
Train employees on the new procedure

Question 9

Of the following options, select all that are expectations the public have for blood banks:

Answer 9

A service performed at 99.9% perfection
A quality service
Increased testing and screening

Question 10

The result of blood being defined as “Biologic” in 1970 was the FDA defining “blood” as a a drug product which would have to adhere to the good manufacturing processes as outlined in the Code of Federal Regulations
TRUE OR FALSE

Answer 10

True

Question 11

Failure to follow the FDAs guidelines, “Good Manufacturing Processes” when creating blood products can result in:

Answer 11

Suspended blood product production - resulting in lost revenues
Licenses revoked
legal indictment of all personnel involved

Question 12

Quality Assurance

Answer 12

Evaluation and monitoring of all aspects of a process or system.

Question 13

Quality Control

Answer 13

Activities performed to insure reagents /equipment / techniques used are functioning

Question 14

Process Control

Answer 14

Assures that procedures were followed and the products made are of the highest standards

Question 15

Trackability

Answer 15

A sequential audit trail

Question 16

Traceability

Answer 16

What was done, when, & by whom?

Question 17

Validation

Answer 17

Documented evidence that provides assurance that a specific process will consistently produce an appropriate result

Question 18

Competency Testing, performed once a year, assesses a department member’s :

Answer 18

Interpersonal Skills
Compliance to all accreditation requirements
Critical Decision Making Skills
Technical Skills

Question 19

Competency testing evaluates:

Answer 19

Familiarity with pre-analytical factors and problems
Adherence to all SOPs
Analytical skills to include accuracy and timeliness of results
Familiarity of post-testing evaluation and interpretation

Question 20

Error management is a requirement of the FDA as a method to detect errors, deviations, accidents, and incidents. An Error management system is in place to:

Answer 20

Prevent recurrence of similar errors
Determine corrective action to errors
Prevent and detect errors

Question 21

Some blood bank errors must be reported to prevent being held liable including:

Answer 21

Reporting when a unit was transfused but it should’ve been deferred (and destroyed).
Discovery of or Use of incorrectly labeled units
Detection of contamination in a unit

Question 22

Veno-Arterial (VA)

Answer 22

Used for cardiopulmonary deficits

Question 23

Veno-Venous system (VV)

Answer 23

Used for pulmonary deficits

Question 24

An infant can stay on ECMO up to 3 weeks!
true or false

Answer 24

true

Question 25

Which of the following are risks for a patient on ECMO?

Answer 25

Transfusion
Infection
Clots
Bleeding
Stroke
Air Bubbles

Question 26

A thromboelastographic instrument, which is utilized to determine blood product usage and necessity, may be referred to by what 3letter term:

Answer 26

TEG

Question 27

ECMO stands for

Answer 27

Extracorporeal
Membrane
Oxygenation