[SEM2] SURGERY Flashcards
(120 cards)
Which of the following statements regarding tuberculous enteritis is incorrect?
Choices:
A. Primary infection usually results from ingestion of non-pasteurized milk contaminated with Mycobacterium bovis.
B. Secondary infection results from ingestion of bacilli contained in contaminated sputum.
C. The duodenum is the site of involvement in 85% of patients.
D. Infection may be indistinguishable from Crohn’s disease or cancer.
E. Approximately one-half of patients with colonic or ileocecal disease may be treated medically without surgery.
What percentage of bile duct injuries are identified intraoperatively?
Choices:
A. 85%
B. 5%
C. 25%
D. 50%
E. 10%
Thyroid hormone production is inhibited by:
Choices:
A. Epinephrine
B. Glucocorticoids
C. Human chorionic gonadotropin
D. Alpha-fetoprotein
A 40-year-old female, status post (S/P) modified radical mastectomy (MRM), chemotherapy, and radiation therapy, was given a SERM. Which of the following examinations must be done for monitoring?
Choices:
A. CBC every 6 months
B. Pelvic ultrasound annually
C. Chest X-ray (CXR)
D. Breast MRI
Thyroglossal duct cysts are most commonly located:
Choices:
A. On the anterior border of the sternocleidomastoid muscle
B. In the midline at the level of the hyoid
C. Over the medial clavicular head
D. In the midline just superior to the thyroid gland
A 20-year-old college student recovers from a bout of severe pancreatitis. He has mild epigastric discomfort, bloating, and loss of appetite. Ultrasound shows a cystic mass around the stomach that increased in size over 3 weeks. What should be the next step in management?
Choices:
A. Percutaneous drainage of the cyst
B. Laparotomy and internal drainage of the cyst
C. Excision of cyst
D. Total pancreatectomy
E. Administration of pancreatic enzymes
A 60-year-old woman presents with abdominal pain. A CT scan reveals an omental mass. The most likely diagnosis is:
Choices:
A. Desmoid tumor
B. Liposarcoma of the omentum
C. Omental infarction
D. Metastatic carcinoma
True about SILS (Single-Incision Laparoscopic Surgery) except:
Choices:
A. Umbilical scar incision
B. Conventional tools employed
C. Accessible extraction site
D. All are true
The major deterrent to the use of adjuvant chemotherapy is:
Choices:
A. Risk of infection
B. High cost of chemotherapeutic drug
C. Response rate is less than 20%
D. Thrombocytopenia
A 56-year-old man presents with a 2-day history of fever, nausea, and left lower quadrant pain. His WBC count is 14,000 cells/µL. CT shows a thickened sigmoid colon with fat stranding and a 5-cm pelvic abscess. What is the optimal management?
Choices:
A. Immediate sigmoid colectomy and drainage of abscess
B. CT-guided drainage followed in 6 weeks by colectomy and sigmoidectomy
C. CT-guided drainage alone
D. IV antibiotics followed in 6 weeks by colectomy and sigmoidectomy
A 50-year-old male with a history of peptic ulcer disease presents with hematemesis and melena. After aggressive resuscitation (3L crystalloids + 3L blood) over 6-8 hours, he remains hypotensive (BP 80/60, PR 140). What is the next best step?
Choices:
A. Emergency upper endoscopy
B. Emergency angiography
C. Prepare for emergency laparotomy
D. Continue volume replacement
On abdominal exploration for a suspected carcinoid tumor, a 2-cm mass is found in the terminal ileum. No liver lesions are detected preoperatively or intraoperatively. What is the best treatment?
Choices:
A. Local excision of the tumor
B. Right hemicolectomy
C. Ileal resection only
D. Liver biopsy to rule out micrometastasis
Which type of head and neck cancer is associated with Epstein-Barr Virus (EBV)?
Choices:
A. Squamous cell carcinoma
B. Nasopharyngeal carcinoma
C. Oropharyngeal carcinoma
D. Laryngeal carcinoma
Mutations in the tumor suppressor gene p53 are strongly associated (up to 70%) with which malignancy?
Choices:
A. Colon cancer
B. Breast cancer
C. Esophageal cancer
D. Thyroid cancer
B. Breast cancer
⸻
High-Yield Rationale:
• p53 (TP53 gene) mutations are most famously linked to Li-Fraumeni syndrome, a hereditary cancer syndrome.
• In Li-Fraumeni, breast cancer is the most common malignancy, especially in young women, and p53 mutations are seen in up to 70% of cases.
• While p53 is involved in many other cancers (including colon and esophageal), none have as strong or consistent an association as breast cancer.
⸻
Why Others Are Incorrect:
• A. Colon cancer: Often involves APC and KRAS mutations early; p53 mutations occur later in adenoma-carcinoma sequence.
• C. Esophageal cancer: p53 is involved but not with a 70% prevalence; environmental risk factors play a larger role.
• D. Thyroid cancer: Most often linked to RET/PTC rearrangements, BRAF, and RAS mutations — not p53.
Which gas is poorly soluble in blood?
Choices:
A. Nitrous oxide
B. Carbon dioxide
C. Oxygen
D. Nitrogen
A 54-year-old man presents with 2 months of abdominal pain and weight loss. Imaging reveals a carcinoid tumor in the mid-ileum confirmed by frozen section. Which statement about this tumor is true?
Choices:
A. Carcinoid tumors rarely metastasize
B. Midgut carcinoid tumors often metastasize to the liver
C. Carcinoid tumors never produce hormone-related symptoms
D. Surgery is not indicated unless symptomatic
The inferior adrenal artery originates from:
Choices:
A. Aorta
B. Renal artery
C. Inferior phrenic artery
D. Celiac artery
A 38-year-old woman presents with nausea, vomiting, distention, and obstipation. Imaging shows a markedly dilated, kidney-shaped loop of bowel extending from the right lower quadrant to the left upper quadrant. What is the best treatment?
Choices:
A. Immediate surgical resection
B. Flexible sigmoidoscopy with decompression
C. IV antibiotics and observation
D. Emergency colectomy
What is the imaging of choice for a 7-cm painless mass on the upper thigh?
Choices:
A. Plain X-ray
B. Ultrasound
C. CT scan
D. MRI
Which statement is true regarding appendiceal carcinoid tumors?
Choices:
A. Tumors smaller than 2 cm are typically benign
B. All appendiceal carcinoids require right hemicolectomy
C. Appendiceal carcinoids frequently cause carcinoid syndrome
D. Appendectomy is insufficient treatment for any carcinoid tumor
A 30-year-old woman at 28 weeks of gestation presents with a 24-hour history of right upper quadrant pain. WBC is 18,000/µL. Ultrasound shows a normal gallbladder and viable fetus; appendix is not visualized. What is the next best step?
Choices:
A. Repeat ultrasound in 6 hours
B. Start antibiotics and observe
C. Obtain magnetic resonance imaging (MRI) and proceed with appendectomy if positive
D. Immediate exploratory laparotomy
Which of the following is NOT part of standard follow-up care for head and neck tumor patients?
Choices:
A. Annual follow-up on year 4
B. Close follow-up during the first 2 years
C. Chest imaging annually for smokers
D. Thyroid function tests after radiation to the neck
A 44-year-old man was diagnosed with colon cancer involving the sigmoid and transverse colon. His father, paternal uncle, and sister also had colon cancer. No adenomatous polyps were seen on pathology. What is the most likely diagnosis?
Choices:
A. Familial adenomatous polyposis (FAP)
B. Lynch syndrome I
C. Peutz-Jeghers syndrome
D. Juvenile polyposis
B. Lynch syndrome I
Rationale:
◓Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer, HNPCC):
🔵 Autosomal dominant
🔵 No polyposis
🔵 Proximal colon preference (but can be multiple)
🔵 Early age of onset
◓FAP involves hundreds to thousands of polyps
◓Peutz-Jeghers and Juvenile Polyposis are hamartomatous polyposis syndromes, typically with visible polyps.
What is the best prognostic indicator for breast cancer?
Choices:
A. Tumor size
B. Estrogen receptor status
C. Lymph node involvement
D. Histologic grade