SURG2 FINALS Flashcards
(100 cards)
Most breast cancers are estimated to have a volume-doubling time of?
A. 1 to 2 years
B. 3 to 5 years
C. 4 to 6 weeks
D. 2 to 12 months
A patient with a 1-cm medullary carcinoma of the right thyroid and no clinically significant adenopathy is best treated with:
A. Total thyroidectomy with central lymph node dissection
B. Right thyroid lobectomy and isthmusectomy
C. Right thyroid lobectomy and subtotal left thyroidectomy
D. Total thyroidectomy
According to the Bismuth-Corlette classification system, perihilar cholangiocarcinomas extending into the right secondary intrahepatic ducts are classified as:
A. Type IV
B. Type IIIa
C. Type IIIb
D. Type I
B. Type Illa
Rationale:
The Bismuth-Corlette classification is used to describe perihilar (Klatskin) cholangiocarcinomas based on how far the tumor extends into the biliary tree:
* Type I: Below the confluence of the right and left hepatic ducts
* Type II: Involves the hepatic duct confluence
* Type Illa: Extends into right secondary intrahepatic ducts
* Type Illb: Extends into left secondary intrahepatic ducts
* Type IV: Involves both right and left second-order ducts (multifocal)
High-Yield Point:
Type Illa involves extension into the right biliary tree, impacting surgical resectability and planning.
At what week of human embryonic development does the appendix appear as an outpouching from the caudal limb of the midgut?
A. 4th week
B. 8th week
C. 5th week
D. 6th week
B. 8th week
Rationale:
The appendix develops as a diverticulum from the caudal limb of the midgut loop during the 8th week of embryonic life. Initially, it appears as a small bud from the cecum, which itself develops earlier (around the 6th week). The appendix elongates as the cecum grows, and its final position varies due to differential growth and rotation of the gut.
High-Yield Point:
The 8th week is a critical period for the formation of many GI tract derivatives, including the appendix.
Based on the Alvarado scoring system, which parameter is given a score of 2 if present?
A. Tenderness at the right iliac fossa
B. Shift to the left of neutrophils
C. Anorexia
D. Fever >36.3°C
What is the most important prognosticating factor in soft tissue sarcoma?
A. Depth of invasion
B. Tumor size
C. Locoregional invasion
D. Histologic grade
Innervation of the appendix is derived from sympathetic elements contributed by the superior mesenteric plexus from which spinal level?
A. T4–T8
B. T12–L3
C. T10–L1
D. T6–T10
Appendiceal perforation usually occurs at what site?
A. Mesenteric border
B. Antimesenteric border
C. Base
D. Tip
Which of the following is a common cause of acute (suppurative) thyroiditis?
A. Escherichia coli
B. Pseudomonas aeruginosa
C. Staphylococcus aureus
D. Streptococcus species
One year after surgery, after several previously normal levels, serum CEA determination now shows elevated values. You should now suggest:
A. Adjuvant chemotherapy
B. Repeat determination after 2 months
C. Exploratory laparotomy
D. Complete work-up for metastasis
Most common true diverticulum of the GIT
A. Ileal diverticulum
B. Jejunal diverticulum
C. Duodenal diverticulum
D. Meckel’s diverticulum
Which segment of the primitive gut develops into the ascending colon and proximal transverse colon?
A. Hindgut
B. Foregut
C. Ectoderm
D. Midgut
Which of the following is NOT included in the Gail model for assessing breast cancer risk?
A. Family history of breast cancer
B. Age at first live birth
C. Age at menarche
D. Previous exposure to radiation therapy
E. Previous biopsy revealing atypical hyperplasia
Small intestine: most common benign tumors found in autopsy series
A. Cyst
B. Adenomas
C. Myoma
D. Leiomyomas
What is the mode of action of alkylating agents?
A. Binding of tubulin in the S phase and blocks polymerization
B. Causes damage by interfering with DNA or RNA synthesis
C. Cross-linking the two strands of DNA or direct DNA damage
D. Substitutes for purines or pyrimidines in nucleic acid synthesis
First diagnostic test to order for a solitary thyroid nodule
A. Radioactive iodine scan
B. Fine needle aspiration (FNA)
C. CT or MRI
D. Core needle biopsy
Relaxation of the sphincter of Oddi in response to a meal is largely controlled by which hormone?
A. Ghrelin
B. Cholecystokinin (CCK)
C. Gastrin
D. Motilin
E. Secretin
What percentage of the bile acid pool is reabsorbed in the ileum via enterohepatic circulation?
A. 50%
B. 75%
C. 95%
D. 25%
E. 90%
What is the only vascularized suspensory ligament of the spleen?
A. Gastrosplenic ligament
B. Splenorenal ligament
C. Phrenosplenic ligament
D. Splenocolic ligament
B. Splenorenal ligament
✅ Rationale (Based on Your Document):
From the [Spleen lecture document], the spleen is held in place by several suspensory ligaments, but only one is vascularized:
🌟 Splenorenal ligament:
🔹 Connects spleen to the posterior abdominal wall (near left kidney)
🔹 Contains the splenic artery and vein
🔹 Only ligament carrying vascular supply to the spleen.
📌 Other Ligaments (Non-vascularized):
A. Gastrosplenic ligament
🔸 Connects spleen to stomach
🔸 Contains short gastric vessels, but not the main splenic vessels
C. Phrenosplenic ligament
🔸 Connects diaphragm to spleen
🔸 Non-vascularized
D. Splenocolic ligament
🔸 Connects spleen to colon
🔸 Non-vascularized
Small intestine: most common benign small bowel lesion that produces symptoms
A. Adenomas
B. Leiomyomas
C. Cyst
D. Cystadenoma
A 50-year-old male with a 3×3 cm preauricular lesion involving the superficial lobe of the parotid, biopsy shows malignancy, no facial nerve symptoms. What is the next step?
A. Enucleation
B. Superficial parotidectomy
C. Radiotherapy
D. Total parotidectomy
Treatment of malignant neoplasms of the small intestines
A. Radiotherapy
B. Wide resection including regional lymph nodes
C. Segmental resection and primary anastomosis
D. Observation
Patient with bilirubin 3 mg/dL, albumin 3 mg/dL, INR 3, minimal ascites, alert and coherent. What is true regarding surgical mortality?
A. Overall surgical mortality is 80%
B. Overall surgical mortality is 30%
C. Overall surgical mortality is 10%
D. None are true
Which of the following does NOT stimulate parietal cells?
A. Gastrin
B. Acetylcholine
C. Somatostatin
D. Histamine