Sensory Systems Flashcards

(33 cards)

1
Q

what is the receptive field?

A

the specific area that a receptor responds to

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what do all sensory receptors transduce the adequate stimulus into?

A

a depolarisation, the receptor generator potential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what does the size of the receptor potential encode?

A

the intensity of the stimulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what does the receptor potential then evoke?

A

firing of action potential for long distance transmission

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what does the frequency of the action potential encode?

A

the size of the stimulus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what determines acuity?

A

the density of innervation and size of receptive fields

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are A beta afferent fibres?

A

they are large myelinated fibres sensing touch, pressure and vibration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what are A omega afferent fibres?

A

small myelinated fibres sensing cold, fast pain and pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are C afferent fibres?

A

unmyelinated fibres sensing warmth, slow pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what primary afferent fibres mediate proprioception?

A

a alpha and A beta fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what type of fibres are mechanoreceptive fibres?

A

> A alpha

> A beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

where do mechanoreceptive fibres synapse in?

A

the cuneate and gracile nuclei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

where do the 2nd order mechanoreceptive fibres project to?

A

> reticular formation
thalamus
cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what fibres are the thermoreceptive and nociceptive fibres?

A

A omega and C fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

where do thermoreceptive and nociceptive fibres synapse?

A

in the dorsal horn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

where do second order mechanoreceptor fibres cross over?

A

in the brainstem

17
Q

where do thermoreceptive and nociceptive fibres cross the midline?

A

in the spinal cord

18
Q

where do the thermoreceptive and nociceptive fibres project to?

A

reticular formation
thalamus
cortex

19
Q

how will damage to the dorsal column affect sensory information?

A

there will be loss of touch, vibration, proprioception below lesion on the ipsilateral side

20
Q

how will damage to the anterolateral quadrant affect transmission of sensory information?

A

there will be loss of nociceptive and temperature sensation below the lesion on contralateral side

21
Q

where is the ultimate termination of sensory information?

A

the somatosensory cortex of the postcentral gyrus

22
Q

how are the endings of sensory fibres grouped together?

A

they are grouped according to the location of the receptors

23
Q

what produces a sensory homunculus?

A

grouping of ending of sensory nerve fibres according to the location of their receptors. the extent of the representation is related to the density of receptors in each location.

24
Q

describe the action potential firing rate in a rapidly adapting neuron when there is a prolonged stimulus

A

action potential are fired at the beginning of the stimulus then after a brief period of time they stop firing. they fire again when the stimulus stops.

25
what does convergence reduce?
acuity
26
what is lateral inhibition?
activation of one sensory input causes synaptic inhibition of its neighbours giving a better definition of boundaries and cleaning up sensory information
27
describe how opioid peptides (endorphins) "close the gate" and inhibit A omega and C neurons
inhibitory interneurons release opioid peptides that inhibit transmitter release from A omega and C fibres
28
describe gate closing in segmental control
activity in A alpha and beta fibres activates inhibitory interneurons that inhibit neurotransmitter release from A omega and C fibres
29
what do prostaglandins sensitise?
nociceptors to bradykinin
30
how do NSAIDs work as an analgesic?
they block cyclo-oxygenase that generates prostaglandins
31
how do local anaesthetic work?
they block Na+ action potential and therefore all axonal transmissions
32
how do opiates work?
> reduce the sensitivity of nociceptors > block transmitter release in the dorsal horn > activate descending inhibitory pathways
33
how does trans cutaneous electrical nerve stimulation?
> activation of large diameter mechanoreceptor fibres in the same segment as the stimulus > this stimulates the release of endogenous opioid peptides from interneurons in the dorsal horn > this inhibits synaptic transmission between primary afferent fibres and other fibres.