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Flashcards in Sepsis Deck (7)
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1

What is sepsis?

Systemic inflammatory response to infection
Life threatening organ dysfunction caused bacteraemia and dysregulated host response to infection
Medical emergency

2

Clinical presentation

Fever, Rigors, Sweats
Tachycardia
Tachypnoea
Hypotension
Pain, guarding
PR blood
N&V
Diarrhoea
Constipation

3

Diagnosing sepsis

SIRS Criteria
If you have 2 or more SIRS + infection then you have sepsis
- temperature >38 <36
- heart rate >90
- resp rate >20
- WCC >12,000 or <4,000

4

Investigations

Bloods - WCC, Platelets, CRP
Cultures - blood, stool, urine
Microscopy - stool, urine, sputum
Serology
PCR

5

Management

Give 3, take 3
- give high flow O2
- give IV fluids
- give IV antibiotics
- take blood cultures
- take FBC and lactate (measure of tissue death)
- take hourly urine output

6

Antibiotics (emperic formula)

Amoxicillin - strep, enterococcus
Metronidazole - anaerobes
Gentamicin - coliforms
Administer for 10-14 days

7

Septic shock

Sepsis induced hypotension
Hallmarks of sepsis + at lease 1 acute organ dysfunction