Flashcards in Session 2-Introduction To DNA Deck (12):
Which groove is used for DNA protein binding and why?
Major groove because it has the most space for protein to bind to
How is 2m of DNA packaged in a cell?
DNA wraps around special proteins called HISTONES which form loops of DNA called NUCLEOSOMES. These nucleosomes coil and stack together to form fibres called CHROMATIN. This in turn forms larger loops and coils to form CHROMOSOMES.
What is a gene?
Basic unit of genetic information, carried on a specific locus on a chromosome
What are nucleic acids?
Polynucleotides (linear polymers of nucleotides)
What are the two types of pentose sugars?
Ribose (in RNA)-OH on 2C
2-deoxyribose (in DNA)-H on 2C
Which bases are purines? (Remember: angels are pure)
Adenine and Guanine
Which bases are pyrimidines?
How are nucleotides joined?
Describe the polarity in a DNA molecule
The chain has a 5'P (phosphate end of the chain) and a 3'OH (OH on 3C in deoxyribose)
How many hydrogen bonds are between G and C?
How many hydrogen bonds are between A and T or A and U?