Session 4 Flashcards
(46 cards)
Describe the physiological responses involved in stress
Physiological response to a stressful event: Fight or flight (Cannon, 1932)
Short term changes to mobilise for activity
Mainly triggered by catecholamines (adrenaline and noradrenaline)
- Increased oxygen availability (breathing, increased haematocrit)
- Enhanced mental functioning (sensory awareness, alertness)
- Increased fuel availability (liberation of glucose, protein breakdown, insulin resistance (increased blood sugar))
- Conservation of energy resources (diversion of blood away from these parts of the body): digestive system and sexual response
- Preparation for tissue damage/fatigue: fluid conservation, blood clotting, endogenous analgesia, immune and inflammatory response
- Enhanced physical functioning: cardiac output, blood pressure, sweating, muscle responsiveness
- The fight-flight response involves the sympathetic branch of the autonomic nervous system as a fast, first-wave response and the endocrine pathways of the hypothalamic-pituitary-adrenal (HPA) axis as a slower, second wave response.
The adrenal medulla is stimulated to produce stress hormones such as adrenaline and noradrenaline which causes stimulation of the heart and lungs and the diversion of energy away from unnecessary functions such as saliva production, digestion and reproduction.
Describe the HPA axis
The HPA axis is activated so the hypothalamus releases corticotrophin releasing factor (CRF) which then sets off a cascade of endocrine events culminating in the release of cortisol and other hormones from the adrenal cortex. It results in an increase in blood sugar levels and metabolic rate. It also influences the regulation of blood pressure, the immune system and the inflammatory response.
Explain why stress can have positive and negative consequences
Stress (=> adrenaline) can boost performance to an optimal level but beyond that alert level, you experience anxiety and disorganisation.
Long term stress response is damaging – General Adaptation Syndrome (Selye 1956)
3 stages:
- Alarm: an immediate physical response to stress that prepares us for fight-flight
- Resistance: our body attempts to resolve the stress and return to normal, but if the stressor continues we will remain in a physiologically active state
- Exhaustion: if the stressor continues indefinitely the physical strain on our body will lead to exhaustion, illness or death
Under prolonged periods of stress the HPA axis can become dysregulated and result in chronically elevated levels of cortisol. In the long term this will have negative effects, such as the accumulation of abdominal fat and the wasting of bone and muscle tissue, also leads to sleep problems, reduced sexual function, reduced fertility, increased depression and anxiety.

Define stressors and describe tools to measure stress based on stressors
Modern life:
- Frequent daily hassles and chronic stressors e.g. being stuck in traffic, stuck in a job you don’t like, poor housing (things we feel like we have little control over), dealing chronic illness
- Physiological response ill suited to these form of stress
Measuring stress: efforts to develop objective measure of stress resulted in interest in stressors:
- ‘Stressful life events’ (Holmes and Rahe 1967) (they identified situations that required a lot of adaptation and change and gave a weighting to each event e.g. death of a spouse, divorce, moving house or school)
- Daily hassles and uplifts (Kanner et al 1981) e.g. missing the bus, losing car keys
Use the transactional model to explain stress as a process
Physiology of stress helps understand how and why stress may have a direct impact on health.
But how to account for…?
- Differences between individuals
- Different impact of different stressors
- Stress response in absence of direct threat
Bringing it all together: the transactional model
Subjectivity of stress: different things may be stressful for different people at different times
Process of interaction between a person and what’s going on in the outside world
Stress is a result of how people appraise events and their ability to cope with them

Define Primary and Secondary Appraisal, and Reappraisal
Primary Appraisal:
Is this event a threat? How bad could it be? (Benign, challenging, threatening)
Secondary Appraisal:
Do I have the resources or skills to cope?
Reappraisal:
- Reconsider the situation once you have tried to cope with it (may decide it’s more or less stressful than thought)

Identify important factors that moderate the impact of stress
Control – if you feel like you have very little control, it makes the stressor seem even more stressful
Social Support – can protect you from the effects of adverse stress
Describe the different ways that stress can impact negatively on health
impact of stress on health often down to combination of direct effects on the body, mental health, increases in health risk behaviours e.g. peptic ulcer, type 2 diabetes
The 4 ways stress can impact on health:
- Physical Damage
- Immune System
- Unhealthy behaviours
- Mental health
Explain about stress and physical damage
Physical damage (primarily to cardiovascular system) – atherosclerosis, sudden cardiac death
- With acute stress, there is a possibility of mechanical trauma
- Can lead to diseases like IHD and stress is implicated in Type II Diabetes
- Can be associated with cardiac death
Explain about stress and the immune system
Short/medium term stress:
- Immune system is upregulated
- Prepare to repair damage and resist infection: cell mediated immunity e.g. lymphocytes
- Prepare to fight off pathogens: antibodies, B-cells
Longer term stress: depressed immune function, inflammation: cortisol (HPA axis has negative feedback loop)
- More evidence for stress and immune-related effects
- Delayed WBC production after loss of spouse (Schleifer et al, 1993)
- Delayed wound healing in Alzheimer’s caregivers (Kiecolt-Glaser et al, 1995)
Stress a factor in URTIs, herpes virus, autoimmune diseases (e.g. RA, IDD, MS). Some evidence for impact in cancer and AIDS. Cohen and Herbert (1996)

Explain about stress and unhealthy behaviours
Stress and unhealthy behaviours: potential to cause harm to ourselves e.g. turning to cigarettes, alcohol, junk food at the end of a stressful day
Explain about stress and mental health
- Thinking more rigid and extreme under stress
- Prone to cognitive distortions (Beck 1976) – overgeneralization (thinking everything is always bad), catastrophising (thinking the worst), personalization (thinking this is all my fault).
- Rumination (compulsively focused attention on the symptoms of one’s distress, and on its possible causes and consequences, as opposed to its solutions – over and over; negative reinforcement – stuck in a cycle)
- Lack of control and learned helplessness (stop trying to do anything about it) – anxiety and depression => low motivation / downward spiral of illness
Outline strategies for stress management
- Cognitive strategies e.g. cognitive restructuring, hypothesis testing
- Behavioural strategies: skills training e.g. assertiveness, time-management
- Emotional strategies: counselling, emotional disclosure, social support
- Physical strategies: relaxation training, biofeedback, exercise
- Non-cognitive strategies: drugs (medication)
What are the Signs and Symptoms of Stress?
Cognitive symptoms:
- Memory problems
- Inability to concentrate
- Poor judgement
- Seeing only the negative
- Anxious or racing thoughts
- Constant worrying
Emotional symptoms:
- Moodiness
- Irritability or short temper
- Agitation, inability to relax
- Feeling overwhelmed
- Sense of loneliness and isolation
- Depression or general unhappiness
Physical symptoms:
- Aches and pains
- Diarrhoea or constipatin
- Nausea, dizziness
- Chest pain, rapid heartbeat
- Loss of sex drive
- Frequent colds
Behavioural symptoms:
- Eating more or less
- Sleeping too much or too little
- Isolating yourself from others
- Procrastinating or neglecting responsibilities
- Using alcohol, cigarettes or drugs to relax
- Nervous habits (e.g. nail biting, pacing)
Describe the range of factors that patients with chronic illness have to cope with
- Illness-related
- Socioeconomic impact
- Other life-events
Explain about illness-related factors patients have to cope with
Illness-related
- Diagnosis: emotional responses (e.g. shock, anxiety, depression, denial, anger, fear, etc)
- Physical impact pain, limited mobility, other symptoms
- Treatment: anxiety, discomfort, impact on body image etc
- Hospitalisation: loss of autonomy, privacy or status; possible removal from usual support network etc
Adjustment (Illness-related):
- Biographical disruption
- Change in identity (sick-role, stigma, etc)
- Chronic nature of illness i.e. change may be indefinite – you never know when you’re going to have good days or bad days
- With terminal illness – acknowledgement of own mortality
Explain about socioeconomic factors patients have to cope with and give examples of life events patients may have to cope with
Socioeconomic impact
- Financial problems, if work affected
- Social problems – housing, childcare etc
- Relationship problems, family, friends, colleagues, etc
Different combinations of issues for different patients but all share need for adjustment
Patients also have to cope with other life events:
- Family: bereavement; divorce; marriage; family health; pregnancy; family unemployment
- Personal: imprisonment; personal achievement; change in school / residence; sexual difficulties; change in habits; holidays; Christmas
- Workplace: dismissal; retirement; job change; change in responsibilities/conditions…
- Financial: change in financial state; mortgage
What is Emotion-Focussed Coping?
Emotion focussed coping = change the emotion
- Behavioural approaches: do something e.g. talking to friends, alcohol, finding a distraction, praying for guidance or strength, humour, getting upset and taking it out on other people
- Cognitive approaches: change how you think about situation e.g. denial, focus on positive aspect of problem – have to give up job you don’t like, chance to do something different – seeing it as a challenge!
What is Problem-Focussed Coping?
Problem-focussed coping = change the problem or your resources
- Reduce demands of stressful situation e.g. find out how to cope with feelings of claustrophobia in mask for radiotherapy
- Trying to find information to help me deal with the problem, making a plasn as to how to deal with it, taking some action to improve the situation, putting aside other activities to concentrate on dealing with the problem
- Expand resources to deal with it e.g. if mobility a problem, focus on physiotherapy exercises, buy a motorised wheelchair etc (Folkman, Schaefer and Lazarus 1979)
There are now new forms of sharing as a coping mechanism (via blogging / tweeting online) which is both emotion-focused and problem-focused (feedback from others gives advice on how to deal with problem)
Why is the effectiveness of coping styles important?
Effectiveness of coping styles is important
- All may help, some will be less adaptive long term
- ‘Active’ coping is associated with better adjustment but chronically ill patients tend to report more ‘passive coping strategies. E.g. depressed patients may struggle with problem-focussed coping.
- In clinical practice, consider a person’s coping style when giving information
Describe ways to aid patients’ coping and give relevant examples of useful approaches for individual patient cases
Increase/mobilise social support
- Some patients may have impoverished social networks e.g. more common with elderly people, men vs. women
- Help patients recognise and mobilise support
- Suggest formal sources of support e.g. social services, community resources, hospital visitors, hospital chaplain, other religious and charitable organisations (self-help)
Increase personal control:
- Pain management
- Self-management programmes e.g. Type 1 diabetes – DAFNE (Dose Adjustment for Normal Eating) self-management course
- Give patient choices – engage with them when writing and reviewing personal care plans
- Take cognitive control e.g. Multiple sclerosis society (resources to aid emotional management) (emotion and problem-focussed ocping)
Prepare patients for stressful events (reduce ambiguity and uncertainty) e.g. preparation for surgery and invasive procedures and treatments
- Effective communication reduces anxiety, self-reported pain, length of stay after surgery, patient adjustment/recovery (e.g. Anderson & Masur, 1983, Johnson 1983)
- Peer contact: pairing pre-op patient with post-op patient was associated with reduced pre-op anxiety and earlier discharge (Kulik and Mahler, 1987)
- Be responsive to individual preferences – some may not want all details!
- Consider special cases – children (e.g. GOSH)
Stress management techniques (see stress learning outcomes)
What are the outcomes of successful coping?
- Tolerating or adjusting to negative events or realities
- Reducing threats and enhancing prospects of recovery, preparing for the future
- Maintaining a positive self image, mastery
- Maintaining emotional equilibrium
- Continuing satisfying relationships with others (Cohen and Lazarus 1979)
Explain why patients with chronic illness are at increased risk of mental health problems
Emotional responses to chronic illness: diagnosis of chronic or life-threatening illness is often associated with depression and anxiety. Compared with general population:
- Depression is 2-3 times more common in people with a chronic illness (e.g. cancer, heart disease, diabetes or musculoskeletal/respiratory/neurological disorder) – an estimated 20% of this population (NICE 2011)
- Anxiety is more common in people with heart disease, stroke and cancer (Clarke & Currie 2009) e.g. MS: anxiety affects approx. 30% sufferers and around 50% will have a major depressive episode during lifetime (MS Society 2009)
Explain about anxiety
Anxiety is a response to a threat:
- Threats to identity, well-being
- Threatening events (surgery, treatment, test results, uncertainty re prognosis (discomfort, disability, death?)\
Unpleasant emotional state, may include feelings of panic or dread
Likely to occur at various stages in illness e.g. diagnosis, awaiting test results, discharge from hospital, illness progression, making lifestyle changes
Sustained anxiety can be associated with unhelpful thinking patterns:
- Increased vigilance for threats (e.g. symptoms)
- Interpret ambiguous information as threatening
- Increased recall of threatening memories
Anxiety disorders: phobia, panic attacks, post-traumatic stress disorder
