Session 4 Flashcards

(46 cards)

1
Q

Describe the physiological responses involved in stress

A

Physiological response to a stressful event: Fight or flight (Cannon, 1932)

Short term changes to mobilise for activity
Mainly triggered by catecholamines (adrenaline and noradrenaline)

  • Increased oxygen availability (breathing, increased haematocrit)
  • Enhanced mental functioning (sensory awareness, alertness)
  • Increased fuel availability (liberation of glucose, protein breakdown, insulin resistance (increased blood sugar))
  • Conservation of energy resources (diversion of blood away from these parts of the body): digestive system and sexual response
  • Preparation for tissue damage/fatigue: fluid conservation, blood clotting, endogenous analgesia, immune and inflammatory response
  • Enhanced physical functioning: cardiac output, blood pressure, sweating, muscle responsiveness
  • The fight-flight response involves the sympathetic branch of the autonomic nervous system as a fast, first-wave response and the endocrine pathways of the hypothalamic-pituitary-adrenal (HPA) axis as a slower, second wave response.

The adrenal medulla is stimulated to produce stress hormones such as adrenaline and noradrenaline which causes stimulation of the heart and lungs and the diversion of energy away from unnecessary functions such as saliva production, digestion and reproduction.

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2
Q

Describe the HPA axis

A

The HPA axis is activated so the hypothalamus releases corticotrophin releasing factor (CRF) which then sets off a cascade of endocrine events culminating in the release of cortisol and other hormones from the adrenal cortex. It results in an increase in blood sugar levels and metabolic rate. It also influences the regulation of blood pressure, the immune system and the inflammatory response.

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3
Q

Explain why stress can have positive and negative consequences

A

Stress (=> adrenaline) can boost performance to an optimal level but beyond that alert level, you experience anxiety and disorganisation.

Long term stress response is damaging – General Adaptation Syndrome (Selye 1956)
3 stages:

  • Alarm: an immediate physical response to stress that prepares us for fight-flight
  • Resistance: our body attempts to resolve the stress and return to normal, but if the stressor continues we will remain in a physiologically active state
  • Exhaustion: if the stressor continues indefinitely the physical strain on our body will lead to exhaustion, illness or death

Under prolonged periods of stress the HPA axis can become dysregulated and result in chronically elevated levels of cortisol. In the long term this will have negative effects, such as the accumulation of abdominal fat and the wasting of bone and muscle tissue, also leads to sleep problems, reduced sexual function, reduced fertility, increased depression and anxiety.

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4
Q

Define stressors and describe tools to measure stress based on stressors

A

Modern life:

  • Frequent daily hassles and chronic stressors e.g. being stuck in traffic, stuck in a job you don’t like, poor housing (things we feel like we have little control over), dealing chronic illness
  • Physiological response ill suited to these form of stress

Measuring stress: efforts to develop objective measure of stress resulted in interest in stressors:

  • ‘Stressful life events’ (Holmes and Rahe 1967) (they identified situations that required a lot of adaptation and change and gave a weighting to each event e.g. death of a spouse, divorce, moving house or school)
  • Daily hassles and uplifts (Kanner et al 1981) e.g. missing the bus, losing car keys
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5
Q

Use the transactional model to explain stress as a process

A

Physiology of stress helps understand how and why stress may have a direct impact on health.
But how to account for…?

  • Differences between individuals
  • Different impact of different stressors
  • Stress response in absence of direct threat

Bringing it all together: the transactional model

Subjectivity of stress: different things may be stressful for different people at different times
Process of interaction between a person and what’s going on in the outside world
Stress is a result of how people appraise events and their ability to cope with them

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6
Q

Define Primary and Secondary Appraisal, and Reappraisal

A

Primary Appraisal:

Is this event a threat? How bad could it be? (Benign, challenging, threatening)

Secondary Appraisal:

Do I have the resources or skills to cope?

Reappraisal:

  • Reconsider the situation once you have tried to cope with it (may decide it’s more or less stressful than thought)
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7
Q

Identify important factors that moderate the impact of stress

A

Control – if you feel like you have very little control, it makes the stressor seem even more stressful

Social Support – can protect you from the effects of adverse stress

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8
Q

Describe the different ways that stress can impact negatively on health

A

impact of stress on health often down to combination of direct effects on the body, mental health, increases in health risk behaviours e.g. peptic ulcer, type 2 diabetes
The 4 ways stress can impact on health:

  • Physical Damage
  • Immune System
  • Unhealthy behaviours
  • Mental health
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9
Q

Explain about stress and physical damage

A

Physical damage (primarily to cardiovascular system) – atherosclerosis, sudden cardiac death

  • With acute stress, there is a possibility of mechanical trauma
  • Can lead to diseases like IHD and stress is implicated in Type II Diabetes
  • Can be associated with cardiac death
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10
Q

Explain about stress and the immune system

A

Short/medium term stress:

  • Immune system is upregulated
  • Prepare to repair damage and resist infection: cell mediated immunity e.g. lymphocytes
  • Prepare to fight off pathogens: antibodies, B-cells

Longer term stress: depressed immune function, inflammation: cortisol (HPA axis has negative feedback loop)

  • More evidence for stress and immune-related effects
  • Delayed WBC production after loss of spouse (Schleifer et al, 1993)
  • Delayed wound healing in Alzheimer’s caregivers (Kiecolt-Glaser et al, 1995)

Stress a factor in URTIs, herpes virus, autoimmune diseases (e.g. RA, IDD, MS). Some evidence for impact in cancer and AIDS. Cohen and Herbert (1996)

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11
Q

Explain about stress and unhealthy behaviours

A

Stress and unhealthy behaviours: potential to cause harm to ourselves e.g. turning to cigarettes, alcohol, junk food at the end of a stressful day

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12
Q

Explain about stress and mental health

A
  • Thinking more rigid and extreme under stress
  • Prone to cognitive distortions (Beck 1976) – overgeneralization (thinking everything is always bad), catastrophising (thinking the worst), personalization (thinking this is all my fault).
  • Rumination (compulsively focused attention on the symptoms of one’s distress, and on its possible causes and consequences, as opposed to its solutions – over and over; negative reinforcement – stuck in a cycle)
  • Lack of control and learned helplessness (stop trying to do anything about it) – anxiety and depression => low motivation / downward spiral of illness
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13
Q

Outline strategies for stress management

A
  • Cognitive strategies e.g. cognitive restructuring, hypothesis testing
  • Behavioural strategies: skills training e.g. assertiveness, time-management
  • Emotional strategies: counselling, emotional disclosure, social support
  • Physical strategies: relaxation training, biofeedback, exercise
  • Non-cognitive strategies: drugs (medication)
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14
Q

What are the Signs and Symptoms of Stress?

A

Cognitive symptoms:

  • Memory problems
  • Inability to concentrate
  • Poor judgement
  • Seeing only the negative
  • Anxious or racing thoughts
  • Constant worrying

Emotional symptoms:

  • Moodiness
  • Irritability or short temper
  • Agitation, inability to relax
  • Feeling overwhelmed
  • Sense of loneliness and isolation
  • Depression or general unhappiness

Physical symptoms:

  • Aches and pains
  • Diarrhoea or constipatin
  • Nausea, dizziness
  • Chest pain, rapid heartbeat
  • Loss of sex drive
  • Frequent colds

Behavioural symptoms:

  • Eating more or less
  • Sleeping too much or too little
  • Isolating yourself from others
  • Procrastinating or neglecting responsibilities
  • Using alcohol, cigarettes or drugs to relax
  • Nervous habits (e.g. nail biting, pacing)
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15
Q

Describe the range of factors that patients with chronic illness have to cope with

A
  • Illness-related
  • Socioeconomic impact
  • Other life-events
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16
Q

Explain about illness-related factors patients have to cope with

A

Illness-related

  • Diagnosis: emotional responses (e.g. shock, anxiety, depression, denial, anger, fear, etc)
  • Physical impact pain, limited mobility, other symptoms
  • Treatment: anxiety, discomfort, impact on body image etc
  • Hospitalisation: loss of autonomy, privacy or status; possible removal from usual support network etc

Adjustment (Illness-related):

  • Biographical disruption
  • Change in identity (sick-role, stigma, etc)
  • Chronic nature of illness i.e. change may be indefinite – you never know when you’re going to have good days or bad days
  • With terminal illness – acknowledgement of own mortality
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17
Q

Explain about socioeconomic factors patients have to cope with and give examples of life events patients may have to cope with

A

Socioeconomic impact

  • Financial problems, if work affected
  • Social problems – housing, childcare etc
  • Relationship problems, family, friends, colleagues, etc

Different combinations of issues for different patients but all share need for adjustment

Patients also have to cope with other life events:

  • Family: bereavement; divorce; marriage; family health; pregnancy; family unemployment
  • Personal: imprisonment; personal achievement; change in school / residence; sexual difficulties; change in habits; holidays; Christmas
  • Workplace: dismissal; retirement; job change; change in responsibilities/conditions…
  • Financial: change in financial state; mortgage
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18
Q

What is Emotion-Focussed Coping?

A

Emotion focussed coping = change the emotion

  • Behavioural approaches: do something e.g. talking to friends, alcohol, finding a distraction, praying for guidance or strength, humour, getting upset and taking it out on other people
  • Cognitive approaches: change how you think about situation e.g. denial, focus on positive aspect of problem – have to give up job you don’t like, chance to do something different – seeing it as a challenge!
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19
Q

What is Problem-Focussed Coping?

A

Problem-focussed coping = change the problem or your resources

  • Reduce demands of stressful situation e.g. find out how to cope with feelings of claustrophobia in mask for radiotherapy
  • Trying to find information to help me deal with the problem, making a plasn as to how to deal with it, taking some action to improve the situation, putting aside other activities to concentrate on dealing with the problem
  • Expand resources to deal with it e.g. if mobility a problem, focus on physiotherapy exercises, buy a motorised wheelchair etc (Folkman, Schaefer and Lazarus 1979)

There are now new forms of sharing as a coping mechanism (via blogging / tweeting online) which is both emotion-focused and problem-focused (feedback from others gives advice on how to deal with problem)

20
Q

Why is the effectiveness of coping styles important?

A

Effectiveness of coping styles is important

  • All may help, some will be less adaptive long term
  • ‘Active’ coping is associated with better adjustment but chronically ill patients tend to report more ‘passive coping strategies. E.g. depressed patients may struggle with problem-focussed coping.
  • In clinical practice, consider a person’s coping style when giving information
21
Q

Describe ways to aid patients’ coping and give relevant examples of useful approaches for individual patient cases

A

Increase/mobilise social support

  • Some patients may have impoverished social networks e.g. more common with elderly people, men vs. women
  • Help patients recognise and mobilise support
  • Suggest formal sources of support e.g. social services, community resources, hospital visitors, hospital chaplain, other religious and charitable organisations (self-help)

Increase personal control:

  • Pain management
  • Self-management programmes e.g. Type 1 diabetes – DAFNE (Dose Adjustment for Normal Eating) self-management course
  • Give patient choices – engage with them when writing and reviewing personal care plans
  • Take cognitive control e.g. Multiple sclerosis society (resources to aid emotional management) (emotion and problem-focussed ocping)

Prepare patients for stressful events (reduce ambiguity and uncertainty) e.g. preparation for surgery and invasive procedures and treatments

  • Effective communication reduces anxiety, self-reported pain, length of stay after surgery, patient adjustment/recovery (e.g. Anderson & Masur, 1983, Johnson 1983)
  • Peer contact: pairing pre-op patient with post-op patient was associated with reduced pre-op anxiety and earlier discharge (Kulik and Mahler, 1987)
  • Be responsive to individual preferences – some may not want all details!
  • Consider special cases – children (e.g. GOSH)

Stress management techniques (see stress learning outcomes)

22
Q

What are the outcomes of successful coping?

A
  • Tolerating or adjusting to negative events or realities
  • Reducing threats and enhancing prospects of recovery, preparing for the future
  • Maintaining a positive self image, mastery
  • Maintaining emotional equilibrium
  • Continuing satisfying relationships with others (Cohen and Lazarus 1979)
23
Q

Explain why patients with chronic illness are at increased risk of mental health problems

A

Emotional responses to chronic illness: diagnosis of chronic or life-threatening illness is often associated with depression and anxiety. Compared with general population:

  • Depression is 2-3 times more common in people with a chronic illness (e.g. cancer, heart disease, diabetes or musculoskeletal/respiratory/neurological disorder) – an estimated 20% of this population (NICE 2011)
  • Anxiety is more common in people with heart disease, stroke and cancer (Clarke & Currie 2009) e.g. MS: anxiety affects approx. 30% sufferers and around 50% will have a major depressive episode during lifetime (MS Society 2009)
24
Q

Explain about anxiety

A

Anxiety is a response to a threat:

  • Threats to identity, well-being
  • Threatening events (surgery, treatment, test results, uncertainty re prognosis (discomfort, disability, death?)\

Unpleasant emotional state, may include feelings of panic or dread
Likely to occur at various stages in illness e.g. diagnosis, awaiting test results, discharge from hospital, illness progression, making lifestyle changes
Sustained anxiety can be associated with unhelpful thinking patterns:

  • Increased vigilance for threats (e.g. symptoms)
  • Interpret ambiguous information as threatening
  • Increased recall of threatening memories

Anxiety disorders: phobia, panic attacks, post-traumatic stress disorder

25
Explain about depression
Depression is an emotional state characterised by persistent low mood, sadness, loss of interest, despair, feelings of worthlessness Tends to be long-term (in the future depression could become the second most leading cause of disability, after ischaemic heart disease) Higher risk of developing depression: * Severity of illness (Moody et al 1990) * Pain and disability (Wulsin et al 1999) * Other negative life events * Lack of social support Comorbid depression can * Exacerbate the pain and distress associated with physical health problems * Adversely affect illness outcomes (NICE 2010)
26
Explain about direct and indirect pathways of how psychological distress can impact on physical health
Direct pathways of psychological distress on health: see stress learning objectives e.g. impact on immune system, functional impairment (Januzzi et al., 2000, Katon 2003) Indirect pathways (Ziegelstein et al, 2000, Katon 2003, 2004) Risk factors and health related behaviour e.g. smoking, drinking, sedentary lifestyle * Compromised quality of life * Impact on coping (e.. with treatment) * Poorer self-management, e.g. depressed patients 2x less likely to adhere to treatment (DiMatteo et all, 2000)
27
Describe barriers to identifying psychological difficulties in patients
**Illness and treatment factors:** * Psychological responses change over time e.g. depression may set in after patient goes home * Symptoms may be attributed to illness or treatment **Patient factors:** * May believe psychological problems are inevitable result of illness and can’t be alleviated * May wish to avoid sounding as if they are complaining or presenting an additional burden to healthcare professionals * May wish to avoid being judged as inadequate or failing to cope * Stigma associated with mental health problems **Healthcare professional factors:** * Outside psychiatric settings, HCPs may avoid asking about psychological problems: believe they are not within their role/ fear overwhelming distress of patient * If patients volunteer information concerning psychological health, HCPs may tend to steer them back on topic of physical condition * Reluctant of some HCPs to label patient as having psychological difficulties
28
Why is it important to recognise psychological problems in patients?
* Recognising possibility of psychological problems: listen/ask about/opportunity to raise problems * Offer help for psychological symptoms: such symptoms are a source of distress in themselves * There are clear links between the psychological and physical health of patients * A concern to all healthcare professionals regardless of their speciality.
29
What are general guidelines for managing mental health problems?
Support in coping (prevention) Counselling and psychological therapies Medication (antidepressants under-prescribed in the chronic illness)
30
Outline NICE guidelines for managing depression
Recognition, assessment and management Mild to moderate depression * Low-intensity psychological interventions * Individual guided self-help (based on CBT – Cognitive Behavioural Therapy - principles); CCBT (Computerised CBT); structured group physical activity; group based CBT; (+group peer support for those with comorbid chronic illness)) Moderate to severe depression * Combine with antidepressants * High-intensity psychosocial interventions – individual CBT; interpersonal therapy, other therapies
31
Outline NICE guidelines for managing anxiety
Generalised Anxiety Disorder * Low-intensity psychological interventions * Individual self-help (based on CBT principles); psychoeducational group * Medication (SSRI) If more severe or persistent * High-intensity psychosocial interventions * Individual CBT; applied relaxation
32
What is the bio-medical model of pain?
Is pain a sensation or emotion? Physical or mental? – Relates to mind-body dichotomy Opposite of pleasure – an emotional experience Early bio-medical theories of pain: * Cut knee (tissue damage) leads to message to brain (feel pain) * Physical damage is sole, direct cause of ‘real’ pain and explains the full extent of the patient experience, more damage causes more pain * Only role for psychology in this model is with aftermath of pain (e.g. anxiety, fear, depression)
33
Explain the limitations of a bio-medical model of pain
* Some people report continuing to experience pain after tissue damage heals * Some people report experiencing pain when no physical damage can be identified * Some people report not feeling too much pain despite severe injuries * Some (but not all) amputees experience phantom limb pain * Placebo effect * Variation in pain reports from people with similar injuries (early research e.g. Beecher 1956, WWII patients) * Positive mood/mindset makes pain experience seem less intense whilst negative mood/mindset makes pain experience seem more intense
34
Distinguish between acute and chronic pain
WHO definition of pain: an unpleasant sensory and emotional experience which is associated with actual or potential tissue damage or is described in terms of such damage **Acute Pain** * Short term e.g. burn finger, break leg * Attracts our attention – so we can do something about the pain - warns of tissue damage * Pain lasts for as long as there is healing (pain is useful, performing a function) * There is action to take: rest, see doctor, medication Chronic Pain (Persistent Pain) * Pain for \>12 weeks, long term, debilitating * Pain is not useful – does not indicate on-going tissue damage * Prolonged rest and medication is not helpful unlike acute pain * Arises from a variety of conditions/diseases or NO KNOWN CAUSE
35
How would you assess pain?
Assessing Pain directly and objectively is difficult because pain is so subjective. Consider * Self report * Assessing behaviour * Psychophysiological measures through observation e.g. sweating, muscle state (rigid, tense) * Measuring effect of pain on other areas of life e.g. mood, daily living * Clinical assessment is important – getting an all-round picture is important
36
Outline the Gate Control Theory of Pain
* Pain is experienced in the brain through complex pathways in body from damage / disease source * Different types of pain fibres have been identified: fast, slow, hot, cold, blunt, sharp * Important neural relays or gates for messages to pass through are located in dorsal horn of spinal cord * Pain is a result of a 2-way process of communication between the brain and the tissue damage or nerve messages * The extent that the gate is open or closed affects the number of pain messages that are received. (The more open the gate, the more pain is felt and vice versa) * Psychological factors e.g. thoughts, beliefs, interpretations, expectations, fear and anxiety interact with physiological events e.g. physical stimuli, tissue damage, nerve messages, medication * Pain is a perception, not just a physical sensation * The same physical event may be perceived differently in different people (or even the same person at a different time). * Pain is never entirely ‘physical’
37
Give examples of what closes and opens the gate
Examples of what Closes the gate * Medication * Counter stimulation * Exercise * Relaxation * Distraction * Positive emotions * Positive beliefs – control * Active life (less time to worry or think about pain) Examples of what Opens the gate: * Injury * Over/under active * Sensitivity of neural system * Stress and tension * Focus on pain – expectation * Negative emotions * Negative beliefs * Minimal involvement in life NEED TO CONSIDER BIOLOGICAL, SOCIAL AND PSYCHOLOGICAL FACTORS
38
What are the limitations of the Gate Control Theory?
* Evidence is consistent with GCT but no actual physical structure has been identified * There is an assumption that there is still some organic basis of pain * Allows that physical and psychological processes interact but still seems them as separate – dualistic thinking * Despite limitations, it has been an enduring theory as it works well to explain how people experience pain in practice * Developments of GCT: neuromatrix theory of pain (the idea that the physical structure is more widely distributed in the whole nervous system, not just at a single location)
39
Discuss how biological, psychological and social factors affect the experience of pain
* E.g. classical conditioning – sound of a dentist’s drill could bring pain * Self-efficacy – sense of control e.g. patients gain more self-efficacy if they are given pain medication pumps they can administer themselves * Negative emotions are associated with more intense experiences of pain * Pain behaviour such as limping or grimacing signal to other people you are in pain and attract sympathy however this makes you more aware of the pain – goes round in a cycle.
40
What is a PMP?
Pain Management Programmes (PMP) – British Pain Society June 2006 * A PMP aims to improve the physical, psychological emotional and social dimensions of quality of life in people with persistent pain using a multidisciplinary team working according to behavioural and cognitive principles rather than consider pain as a disease or damage in biomedical terms (biopsychosocial approach to treating pain, to improve quality of life for patients with chronic pain) * Problems formulated in terms of effects on physical and psychological wellbeing rather than as disease or damage in biomedical terms or as deficits in the individual’s personality or mental health * Central message is that the programme is about helping the patient take control of their pain, rather than the pain being in control. It is not about cure. * For some this is a difficult message to accept, however many people will have already realised that medication or surgery has not been able to ‘fix’ their problem and so they are enthusiastic about something else they can try.
41
Explain about the practice of PMP
Guided, Supported Practice on a PMP * Reinforce an acceptance of reality of chronic pain * Improve fitness, mobility and posture * Address fear of consequences of movement * Develop ways to cope with stress, anxiety, depression, anger – show them different methods, give them choice * Improve ability to relax * Graded return to activities of daily living * Facilitate appropriate medication use * Improve communication skills * Reduce use of unhelpful aids and equipment
42
What are the topics in PMP?
Programme Topics: 4 main parts * Managing thoughts and feelings (CBT – over arching framework, plus ‘new wave’ CBT e.g. Mindfulness) * Active, but pacing self – not over or under active and understanding posture and biomechanics, building achievements (so that you don’t overdo a good day and end up relapsing) * Goal setting * Relaxation Other topics: ‘hurt does not mean harm’, sleep hygiene, communication including assertiveness and anger management, relationships, stress management, maintaining change, including planning for ‘bad’ days, anatomy and physiology of pain and pathways, explanation of differences between acute and chronic pain, physiology of stress response, action and side effects of other drugs
43
Explain about mindfulness for pain management
* Learning to focus on all of the experiences in the present moment, not get stuck in unproductive ruminating over the past or worrying about the future * Instead of trying to change or fight negative thoughts, accept them as ‘just thoughts’ and return attention to the present moment * Take a stance of self-compassion, act with kindness * Can use mindfulness for managing stress, and that in turn helps with pain * MBPM differs from traditional CBT – encourages learning to tolerate focusing attention on pain sensations, but to detach the negative thoughts and related unpleasant emotions from the experience * Pain is inevitable, suffering is optional – John Kabat-Zinn
44
What other important aspects of PMP are there?
* Being believed that the pain is real * Being part of a group – may be different causes of pain, but shared experience of the effect of pain on their lives * Social comparison theory – people often judge others as worse off
45
Describe the patients referred to PMP
* By the time of referral to PMP patients will on average have had 5 years of pain. They will almost always have exhausted all other medical methods of pain relief. * 40% have pain due to an accident, 20% have pain of unknown cause * They are often angry, depressed, anxious, disabled, out of work, have no family difficulties and will have withdrawn from usual social activities e.g. due to combination of mood, finances and pain * Social isolation “You don’t believe you can go out and meet people any more. You don’t believe you have anything to offer them. In a sense your pain becomes your identity. There is nothing else to speak about. All your experience is about pain and being in bed surrounded by 4 walls. It becomes a self-perpetuating cycle.
46
Explain about an inclusion/exclusion criteria and issues with PMPs
Inclusion/exclusion criteria to consider * Communication/language * Mental health * Cognitive ability * Willing to be in a group environment * Level of physical functioning * Social/psychological obstacles that need addressing first Issues with PMPs * Not all patients able to work in groups – need to have language, cognitive and social skills * We know PMPs are effective from systematic reviews but what are the key aspects? * Maintaining the changes that people make – how long will people maintain their improved ability to manage their pain? * Practicalities of follow-up * PMP approach ideally belongs at the beginning of an episode of pain * Specific training for PMP team to ensure consistency