Severe Acute Respiratory syndrome(SARS)

Question 1

Etiology

Answer 1

SARS associated coronavirus (SARS-COV) : +ssRNA enveloped

Question 2

Epidemiology and origin

Answer 2

Guangdong Province Southern China
High morbidity - Back in 2002

Question 3

Reservoir

Answer 3

Bats
Intermediate hosts: civet cats(eaten in China)

Question 4

Transmission

Answer 4

Respiratory droplets(major route)
- Airborne, feco-oral, fomites

Question 5

Incubation period

Answer 5

2-10 days

Question 6

Case definition(WHO)

Answer 6

) - Fever or documented fever AND
- One or more sx of LRTI(cough, dyspnea/SOB) AND
- Radiologic evidence of pneumonia/ARDS
- Confirm with lab diagnostics
CDC:
- Early recognition by clinical & epidemiological features
- Absence of confirmed person to person transmission: no
alternate diagnosis

Question 7

Presentation

Answer 7

● Temperature >100.5F, malaise, headache, myalgia
● Usually no URT sx
- End of prodrome- resp sx begin
● Non productive cough, dyspnea
● Respiratory failure
- Radiologic evidence of pneumonia in 7-10 days
- Lymphopenia

Question 8

Diagnostic Test

Answer 8

ELISA or IFA; Viral DNA by RT-PCR

Question 9

Prevention

Answer 9

• Use tissues, masks, hand hygiene
• Droplet precautions