Shock Flashcards

(55 cards)

1
Q

Why is hypotension bad

A

When blood isn’t circulating, there is no tissue perfusion

Give fluid bolus!

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2
Q

What is hypotension vs shock

A

Hypotension is low blood pressure

Shock is greater oxygen demand than oxygen supply

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3
Q

What can shock lead to

A

with little tissue perfusion, no oxygen delivery, cellular HYPOXIA and metabolic malfunction
Can lead to cell death; end organ damage; multi system organ failure; death

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4
Q

What is systemic tissue perfusion determined by

A

MAP= CO x SVR
CO is HR x SV
SVR is influenced by vessel length, diameter, and fluid viscosity
-CO and SVR determine the etiology of shock

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5
Q

What are the stages of shock

A

Pre-shock: warm, COMPENSATED. tachycardia, perish vasoconstriction, low BP
Shock: compensation OVERWHELMED, signs of organ dysfunction. tachy, dyspnea, metabolic acidosis, oliguria, cold clammy skin
End organ dysfunction: Progressive organ dysfunction, irreversible, coma, death

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6
Q

What are the types of shock

A

Hypovolemic, Cariogenic, Distributive

Obstructive, Neurogenic

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7
Q

What is an arterial line

A

line put into radial/brachial/femoral artery to continuously monitor BP and get recurrent ABGs
NOT for meds

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8
Q

What is a central line

A

placed in vein for delivering critical meds and measuring CVP.
Appropriate for determining fluid status and resuscitation in shock
Can get a triple lumen, double lumen, dialysis cath, Swan-Ganz cath, or PICC line

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9
Q

What is a Peripherally Inserted Central line Catheter (PICC)

A

Sits on top of the heart, small diameter, can keep for a long time but has increased DVT risk

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10
Q

What is CVP

A

pressure near the right atrium that correlated “pre-load” or overall volume status. Can be measured with any central line
If CVP is elevated (5-15 mmHg normal), probably don’t want to give many fluids

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11
Q

What is a Swan-Ganz catheter

A

goes through the RA, RV, and sits in the pulmonary artery. Good for patient in CARDIOGENIC shock

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12
Q

What hemodynamic parameters does a Swan-Ganz measure

A

Pulmonary capillary wedge pressure (norm 5-15)
Cardiac output (norm 4-8 L)
Systemic vascular resistance (norm 1000-1500)

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13
Q

What is the clinical presentation of all types of shock

A

Hypotension (SBP <90 or decrease >40)
Tachycardia (except neurogenic shock, brady)
Oliguria
Mental status change (confusion, lethargy)
Metabolic acidosis
Cold clammy skin (except early distributive and neurogenic- warm flushed)
Later: multi organ failure, coagulopathy

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14
Q

What happens in Hypovolemic shock

A

not enough intravascular volume causes decreased CO and decreased oxygen delivery

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15
Q

What are the causes of hypovolemic shock

A
hemorrhagic (trauma, GI bleed, internal hemorrhage, post-surgical)
Fluid loss (dehydration, n/v/d, burns, acute pancreatitis)
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16
Q

What is the pathophysiology of Hypovolemic shock

A

decreased blood volume leads to decreased SV
deceased SV leads to decreased CO and BP
decreased BP and volume leads to inadequate tissue perfusion (no oxygen)
Compensation: increased SVR (vessels constrict to shunt remaining blood from periphery to heart, lungs, etc)–baroreceptors sense low BP and activate SNS
Switch to Anaerobic metabolism

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17
Q

What are the hemodynamic parameters of hypovolemic shock

A

CVP: decreased
CO: decreased
SVR: increased

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18
Q

What does clinical presentation of hypovolemic shock depend on

A

Amount of blood loss: small is tolerated, large are not

Rate of loss: slow loss allows time for compensation, fast loss leads to shock s/s faster

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19
Q

What do hypovolemic shock patients present with complaints of

A
Hematemesis, hematochezia, melena
N/v/d
abdominal pain
evidence of trauma
Post-op
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20
Q

What are physical signs of hypovolemic shock

A

Dry oral mucosa
Hypotension, tachycardia, tachypnea, decreased JVP/CVP/urine output
Cold clammy extremities, decreased turgor
Confusion
(May be others with underlying pathology)

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21
Q

What diagnostic studies are needed for Hypovolemic shock

A
CBC, CMP, PT/INR (are they bleeding?)
Lactate (marker of tissue perfusion, increase during ANaerobic perfusion)
ABG
CXR/ chest CT
Abd XR/CT
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22
Q

What is increased lactate associated with

A

increased mortality

if high, there is not enough tissue perfusion

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23
Q

How do you manage hypovolemic shock

A

REPLACE VOLUME: crystalloid (saline), Colloid (albumin), blood (PRBC, FFP, Plts)
If SBP <70, can use vasopressors while restoring volume (emergency)

24
Q

What should you monitor when managing hypovolemic shock

A

urine output, peripheral perfusion, mentation

25
What is Cariogenic shock
decreased CO due to pump failure
26
What are the etiologies of cariogenic shock
Ischemia (MI, cardiomyopathy) Valvular HD (ruptures pap muscle/chords, ventricular septum rupture) Arrhythmias (VFib, VTach, complete heart block, AFib, Aflutter) Obstructive (extra cardiac)- massive PE, cardiac tamponade, tension PTX
27
What is the pathophysiology of cariogenic shock
Bad pump causes decreased BP and CO decreased BP/CO turns SNS on, and cause decreased renal perfusion decreased renal perfusion causes sodium and water retention (RAAS) Increased filling pressure (CVP) causes volume overload in lungs (pulm edema) Compensation: increased SVR
28
What are the hemodynamic parameters in Cariogenic shock
CVP: increased PCWP: increased CO: decreased SVR: increased
29
What is the clinical presentation of cariogenic shock
CP Dyspnea Palpitations Fatigue
30
What are the physical signs of cariogenic shock
``` tachycardia, tachypnea, hypotension cool clammy extremities increased JVP muffled heart sounds, new murmur, tachycardia deviated trachea crackles if with pulmonary edema ```
31
What diagnostic studies would you get for cariogenic shock
CBC, CMP, cardiac enzymes, ABG, ECG, CXR, Echo, CT chest
32
How do you manage cariogenic shock
``` treat underlying problem! --MI- oxygen, cath lab --VTach/VF- ACLS --tension PTX- decompression --cardiac tamponade- pericardiocentesis Cardio consult Fluids (VERY cautious, fluid overload) ```
33
What meds may be provided in the management of cariogenic shock
Inotropes (Dobutamine 1st, +/- vasopressors) diuretics anti-arrhythmatics HF meds
34
What is your last resort in cariogenic shock management
Assist devices (LVAD, RVAD, artificial heart) ECMO Heart transplant
35
What are the causes of distributive shock
``` SALAD Sepsis Adrenal Insufficiency Liver disease Anaphylaxis Drugs/meds ```
36
What are the types of vasodilator shock
Distributive and neurogenic shock
37
What is septic shock
inadequate tissue perfusion and oxygen supply when tissues require more while combating systemic infection and septic endotoxins (increased metabolic needs while fighting an infection) -any kind of infection; UTI, PNA, bacteremia, etc.
38
What is "early septic shock"
Vasodilation- initial response to meet increased oxygen needs (HYPERDYNAMIC response) Well compensated, but difficult to maintain Start to see signs of organ impairment due to endotoxins aggravating cellular hypoxia
39
What is the stampede analogy in early septic shock
pro-inflammatory cells outnumber anti-inflammatory cells (malignant intravascular inflammation) causing profound vasodilation
40
What is "late septic shock"
start to see cap leakage and loss of vascular tone, leading to HYPOvolemia and HYPOtension. Cant compensate anymore Vasoconstriction is worse for present hypoxia and causes organ system malfunction (poor perfusion to extremities and internal organs)
41
What is the clinical presentation of septic shock
fever, hypotension, tachycardia warm (early) extremities, then cold (late) confusion
42
What clinical features in elderly/immunocompromised make you suspect septic shock
unexplained hypotension, mental status changes, signs of organ dysfunction
43
What are the hemodynamic parameters of early shock
CVP: decreased (vasodilation) CO: increased SVR: decreased (vasodilation
44
What are the hemodynamic parameters of late shock
CVP: usually decreased (can be increased) CO: decreased SVR: increased
45
What diagnostic studies are important for septic shock
``` LACTATE! CBC/CMP Cultures ABG CXR ```
46
How do you manage septic shock
early goal directed therapy is beneficial Treat underlying problem; Panculture BEFORE abx, then abx empirically until results come back FLUID!!
47
What meds assist in septic shock management
Vasopressors (norepinephrine)
48
What further management options are there for septic shock
ventilator support if indicated (PNA, labored breathing)
49
What is neurogenic shock
loss of sympathetic tone leading to vasodilation and hypotension BRADYCARDIA! (loss of SNS kicks PNS up)
50
What is the etiology of neurogenic shock
spinal cord injury (disruption between brain and spinal cord) closed head trauma w/ brainstem injury
51
What happens to the SNS in neurogenic shock
- Sympathetics usually leave brain stem, down C-spine, exit TL region and release epi/norepi (increased HR, contractility, vasoconstriction) - Disruption of SNS results in unopposed PNS= hypotension, decreased SVR, and normal/bradycardia
52
What is the clinical presentation of septic shock
``` HR normal or brady +/- altered LOC para-quadriplegic absent DTR/hyperreflexia warm extremities (vasodilation) decreased sphincter tone (PNS) ```
53
What are the hemodynamic parameters in septic shock
CVP: normal or low (hypotension) CO: normal or low (decreased HR) SVR: decreased (vasodilation)
54
What diagnostic studies would you get for septic shock
CBC, CMP C-spine XR (C7-T1) Head CT (r/o structural lesions, shift, herniation) Spine CT/MRI
55
How do you manage septic shock
fluids to correct HYPOvolemia | Neurosurg consult asap