SKELETAL MUSCLE RELAXANTS

Question 1

Give the skeletal muscle relaxants

Answer 1

Neuromuscular muscle blocker
Spasmolytics
Antispasmodics

Question 2

Give the MOA

Answer 2

Lack CNS activity but interfere transmission at the neuromuscular endplate

Question 3

Give the steps of neuromuscular transmission

Answer 3

1) Action potential arrives
2) Influx of calcium
3) Release of Ach
4) Bind to the nicotinic receptors
5) Nm ion channel opens
6) Depolarisation leading skeletal muscle contraction

Question 4

Ach is usually removed from teh end plate by 2 ways

Answer 4

Diffusion and acetylcholinesterase

Question 5

Give the classes of NMB

Answer 5

Depolarising and non-depolarising