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DMD 5243 > Skin > Flashcards

Flashcards in Skin Deck (40):
1

macule

flat lesion

2

papule

raised lesion

3

vesicle

a blister

4

acantholysis

loss of intercellular cohesion bt keratinocytes

5

acanthosis

diffuse epidermal hyperplasia

6

hyperkeratosis

thickening of stratum corneum often associate with a qualitative abnormality of the karatin

7

papillomatosis

surface elevation cause by hyperplasia and enlargement of contiguous dermal papillae

8

impetigo

infectious
staph aureus, strep pyogenes
children
crusty pustules on face

9

erysipelas

infectious
strep a
any
sharpy circumscribed erythematous plaque on face/scalp

10

necrotizing fasciitis

infectious
many potential organisms
children
redness, pain evolving into gangrene

11

acne

infectious
proprionibacterium acnes
variable
sebaceous glands get plugges and inflamed, resulting in comedones (blackheads) and pustules

12

ringworm

infectious
fungi
children
red, inflamed, scaly round lesions
(tenea pedis - athletes foot; tinea corporis - ringworm)

13

sporotrichosis

infectious
sporotrichum schenckii (gardeners disease)
any
painless papule, then open sore

14

verruca vulgaris

infectious
HPV
any
small, rough growth resembling a cauliflower or blister

15

herpes simplex

infectious
HSV
any
HSVI - cold sores
HSVII - genital
reside in ganglia

16

erythema multiforme

infectious
HSV, drug induced
any
target lesions or vessicles on skin and mucous membranes

17

molluscum contagiosum

infectious
poxvirus (mcv)
any - very contagious
centrally umbilicated (indentation) red papules

18

scabies

infectious
sarcoptes scabei
any, more common in children
itchy rash on hands/wrist/abs/goin

19

urticaria

inflammatory
mast cell degranulation
any
erythematous, edematous, pruritic plaques

20

psoriasis

inflammatory
inherited disease
any
itchy red lesions with silvery scales/ may also have arthritis

21

lichen planus

inflammatory
immune-mediated disease
any
skin - purple polygonal papules
mucus membranes - lacy lesions (wickams straie), erosions, leukoplakia

22

atopic eczema

inflammatory
usually inherited
any
itchy rash

23

pemphigus vulgaris

bullous
antibodies against intercellular junctions
adults
superficial bullae that easily rupture; mouth first, then skin
(acantholysis is a common feature)

24

bullous pemphigoid

bullous
antibodies agaisnt basement membrane of epidermis
elderly
big, subepidermal bullae of groin, axilla, arms, and mouth

25

nevus

what - benign proliferation of melanocytes
manifestation - depends on location

26

junctional nevus

mole at dermal-epidermal junction

27

compound nevus

mole into dermis

28

intradermal nevus

mole in the dermis only

29

hemangioma

what - common benign tumor of blood vessels
manifestation - strawberry

30

keratoacanthoma

what - common benign tumor, possible from hair follicle
manifestation - rapidly growing crater-like nodule

31

seborrheic keratosis

what - common benign epidermal tumor
manifestation - flat, brown, velvety plaque

32

actinic keratosis

what = benign neoplasm of epidermis
manifesation - rough spots with erythematous base on sun exposed skin

33

basal cell carcinoma

what - malignant tumor of basal layer
mani - pearly nodule

34

squamous cell carcinoma

what - malignant tumr of squamous epithelium
mani - red nodule

35

melanoma

what - malignent tumor of melanocytes
can arise from benign nevus
sun exposure increases risks
can metastasize
prognosis a function of depth invasion

36

4 types of melanoma

superficial spreading
nodular
lentigo maligna
acral lentiginous (found on non hair bearing surfaces)

37

melanoma depth vs survival

less than 1mm = 80-95% 5 year survival
1-2mm = 30-60% 5 year survival
2-4mm = 35% 5 year survival

38

kaposi sarcoma

vascular tumor
malignant tumor of lymph epithelium that intersect blood vessels
mani - red bumps
(high incidence - ashk. jews, aids patients)

39

angiosarcoma

vascular tumor
malignant tumor of endothelial-type cells in blood vessels
mani - bruise-like patterns progressing to lesions

40

puetz-jeghers syndrome

genetic mutation causing GI polyps and mucosal hyperpigmentation
mani - various