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Science for Medicine > Skin > Flashcards

Flashcards in Skin Deck (13):
1

What is the skin?

Combination of tissues with its own blood supply, accounts for 16% total body weight
- largest organ in the body
- acts as major compartment separator
- helps with homeostasis, sensory reception and protection from external environment

2

What are the three layers of the skin?

- epidermis
- dermis
- hypodermis

3

Describe the epidermis

- epithelium
- forms boundary between internal and external compartments

4

Describe the dermis

- connective tissue
- gives structural strength

5

Describe the hypodermis

- fat

6

What are the five layers of the epidermis?

- stratum germinativum
- stratum spinosum
- stratum granulosum
- stratum lucidum
- stratum corneum

7

Describe the stratum germinativum

- bound to basement membrane by hemidesmosomes
- bound to other cells by desmosomes
- regular assortment of organelles
- stem cells

8

Describe the stratum spinosum

- spinous layer
- created after cell death
- cells shrink bu desmosome junctions create spines

9

Describe the stratum granulosum

- defined by presence of keratohyalin granules
- accumulations of protein around keratin intermediate filaments

10

Describe the stratum corneum

- keratohyalin converted to keratin
- disulphide linkages give strength
- no organelles
- desmosomes bind cells
- 30 day turnover

11

What two layers compose the dermis?

- papillary layer
- reticular layer

12

Describe the papillary layer

- loose connective tissue
- irregular interface with epidermis
- cellular e.g. macrophages
- blood vessels
- nerve endings

13

Describe the reticular layer

- dense irregular connective tissue
- collagen bundles in 3 planes
- elastic fibres