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MRCP Dermatology > Skin disorders associated with systemic disease > Flashcards

Skin disorders associated with systemic disease Flashcards

1
Q

Skin disorders assoc. with diabetes

A

Necrobiosis lipoidica
Skin Infection (candida/ staph)
Neuropathic ulcers
Vitiligo
Lipoatrophy
Granuloma annulare

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2
Q

Features of Necrobiosis lipoidica

A
  • shiny, painless yellow/red/brown skin
  • shin
  • surrounding telangiectasia
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3
Q

Features of granuloma annulare

A
  • slightly hyperpigmented papules
  • depressed centrally
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4
Q

Gastric Cancer

A

Acanthosis nigricans

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5
Q

Lymphoma

A

Acquired ichthyosis
Erythroderma

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6
Q

Gastrointestinal and lung cancer

A

Acquired hypertrichosis lanuginosa

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7
Q

Dermatomyositis

A

Ovarian and Lung cancer

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8
Q

Erythema gyratum repens

A

Lung cancer

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8
Q

Erythema gyratum repens

A

Lung cancer

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9
Q

Migratory thrombophlebitis

A

Pancreatic cancer

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10
Q

Necrolytic migratory erythema

A

Glucagonoma

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11
Q

Myeloproliferative disorders

A

Pyoderma gangrenosum (bullous and non-bullous forms)

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12
Q

Sweet’s syndrome

A

Haematological malignancy e.g. Myelodysplasia - tender, purple plaques

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13
Q

Tylosis

A

Oesophageal cancer

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14
Q

What skin conditions can be caused by pregnancy?

A

atopic eruption
polymorphic eruption
pemphogoid gestationis

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15
Q

Features of atopic eruption of pregnancy

A
  • eczematous, itchy red rash
  • no specific treatment is needed
16
Q

Features of polymorphic eruption of pregnancy
and what trimester does this occur in?

A
  • last trimester
  • lesions first appear in abdominal striae
  • pruritic
17
Q

Management of polymorphic eruptiojn of pregnancy

A

emollients
mild potency topical steroids oral steroids

18
Q

Features of pemphigoid gestationis

A
  • pruritic blistering lesions
  • peri-umbilical region first then spread to trunk, back, buttocks and arms
19
Q

Management of pemphigoid gestationis

A

oral corticosteroids are usually required

20
Q

When does pemphigoid gestationis usually present during pregnancy?

A
  • 2nd or 3rd trimester
  • rarely seen in the first pregnancy
21
Q

Skin disorders associated with TB

A
  • Lupus vulgaris
  • erythema nodosum
  • scarring alopecia
  • scrofuloderma: skin breakdown overlying a TB focus
  • verrucosa cutis
  • gumma
22
Q

Features of lupus vulgaris

A
  • most common cutaneous TB in Indian subcontinent
  • affects face, particularly nose and mouth
  • initial lesion = erythematous flat plaque which gradually becomes elevated and may ulcerate

MRCP Dermatology (21 decks)

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