Steven Johnson Syndrome Flashcards
1
Q
What is Steven Johnson Syndrome?
A
severe systemic reaction affecting skin and mucosa
almost always caused by a drug reaction
2
Q
Drugs which can cause SJS?
A
penicillin
sulphonamides
lamotrigine, carbamazepine, phenytoin
allopurinol
NSAIDs
oral contraceptive pill
3
Q
Features of SJS
A
- maculopapular rash with target lesions (characteristic)
- may develop into vesicles or bullae
- Nikolsky sign is positive in erythematous areas
- Mucosal involvement
- Systemic symptoms: fever, arthralgia
4
Q
Patients with suspected SJS can be managed in the community. TRUE/FALSE?
A
FALSE
hospital admission is required for supportive treatment
