Sleep physiology Flashcards Preview

Neurology - Anatomy and Physiology > Sleep physiology > Flashcards

Flashcards in Sleep physiology Deck (20):
1

What generates the circadian rhythm of sleep?

suprachiasmatic nucleus of hypothalamus

2

What is SCN regulated by?

Environment, eg light

3

What does SCN release?

Norepi --> pineal gland

4

What does the pineal gland release?

melatonin

5

What EEG waveform is present when awake with eyes open?

Beta waves - highest frequency, lowest amplitude

6

What EEG waveform is present when awake with eyes closed?

Alpha waves

7

When are theta EEG waves present?

during light sleep, stage N1

8

When are sleep spindles and K complexes on EEG present?

During deeper sleep, stage N2

9

When are delta waves present? What characterizes delta waves?

Delta waves are the lowest frequency, highest amplitude waves. Present during Stage N3, deepest non-REM sleep, aka as slow wave sleep.

10

What EEG waveforms are present during REM sleep?

Beta waves.

11

During what sleep stage does bruxism occur?

Stage N2 (sleep spindles, K complexes)

12

During what sleep stage does sleep walking, night terrors, and bedwetting occur?

Stage N3, delta waves.

13

During what sleep stage is there loss of motor tones, increased brain oxygen use, and variable pulse and pressure occur?

REM sleep (beta waves)

14

During what sleep stage are there dreaming and night boners?

REM sleep

15

What causes extraocular movements during REM sleep?

paramedian pontine reticular formation (conjugate gaze center).

16

How do alcohol, benzos, and barbituates affect sleep?

Decrease REM and delta wave sleep.

17

How does norepi affect sleep?

decrease REM sleep

18

How can bedwetting be treated?

Oral desmopressin > imipramine.

19

What can be useful for night terrors and sleep walking?

Benzos

20

What do the EEG waveforms actually represent?

Thalamus cell action potential firing. Single spike/tonic action potentials when awake, burst type groups of action potentials fired during sleep. Mediated by T-type calcium voltage dependent channels.