Slide 105-142 Flashcards
(24 cards)
The action of the drugs on living tissue. Affected by the form of the drug and the ROUTE of administration.
Pharmacodynamic Phase
What is an INDUCER of CYP450 system?
St. John’s Wort
How do you reduce interactions of drugs with food?
Take 1 hour before or 2 hours after eating.
Monoamine Oxidase Inhibitors (MAOIs) need to avoid _____ foods to prevent spike in blood pressure and possible stroke.
TYRAMINE (wisconsin)
What induces CYP?
Alcohol, caffeine, garlic, grape seed, licorice, St. Johns wort, Tobacco
DO NOT give supplements/foods that interfere with CYP enzymes to patients taking other supplements or any medications.
KNOW
A substance taken into the body by ingestion, inhalation, injection, or absoption that interferes with normal physiological functions and causes harm
Poison
A substance that neutralizes poisons or toxic substances
Antidote
An agent that induces vomiting
Emetic
A substance that adsorbs another substance. Activated Charcoal
Adsorbant
Pumping the stomach
Gastric Lavage
Most common type of poisoning.
Ingestion. Children between 1-5 are most at risk.
Bitter almonds cause what odor?
Cyanide
Garlic causes what odor?
Organophosphates, Arsenic
Fruity causes what odor?
DKA, Isopropyl alcohol
True or False: The majority of poisonings are Unintentional. The majority of DEATHS secondary to poisoning are intentional. Most poisonings occur at home, are by ingestion.
True.
What is the #1 cause of unintentional overdose?
Opioid Narcotics
What is the #1 drug used for intentional overdose?
Acetaminophen
The most commonly reported poison?
Analgesics (acetaminophen)
The least commonly reported poison?
Alcohol
Which is associated with the most deaths?
Analgesics (opioid narcotics)
Which is associated with the least deaths?
Hydrocarbons
The #1 poisonous killer?
Carbon Monoxide
Which methylxanthine is most toxic?
Theophylline
