Small Intestinal Obstruction Flashcards

1
Q

What are causes of small intestinal obstruction in children?

A

Small intestinal obstruction in children can have a wide range of etiologies.

Neonatal intestinal obstructions are often related to specific gastrointestinal pathology such as intestinal atresias, meconium ileus, meconium plug syndrome, small left colon syndrome, Hirschsprung disease, anorectal malformation, necrotizing enterocolitis, malrotation with midgut volvulus, incarcerated inguinal hernia, anterior abdominal wall defects and more.

In older children, intestinal obstruction are also seen in the setting of intussusception, vitelline duct remnants, perforated appendicitis, malrotation with or without midgut volvulus, foreign bodies, tumors and more.

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2
Q

How common is adhesive small bowel obstruction (ASBO) in the pediatric population?

A

Overall, ASBO occurs in 1–6% of children following abdominal surgery [1].

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3
Q

Which patients are at the highest risk for developing ASBO?

A

High rates of ASBO have been reported after the following index operations: ileostomy formation and closure (25%), Ladd procedure for malrotation (24%), and nephrectomy for Wilm׳s tumor (8.9%) [1, 2].

Younger patients who have undergone index operation during infancy are also at higher risk (13%), particularly within two years of the initial operation [3].

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4
Q

Which patients are at lowest risk for developing ASBO?

A

The rate of ASBO is <1% in patients who have undergone appendectomy but may
be more common in patients with perforated appendicitis [1].

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5
Q

How do patients with ASBO present?

A

Patients commonly present with anorexia, crampy abdominal pain, emesis, and obstipation. Lethargy, significant abdominal distension and constant abdominal pain are late findings.

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6
Q

What are the clinical signs and symptoms of bowel ischemia?

A

The signs and symptoms of bowel ischemia can be difficult to determine in the pediatric population.

Peritonitis is an obvious sign. Other indicators are fever, tachycardia and an elevated white blood cell count and lactic acidosis on labora- tory work-up.

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7
Q

What are radiologic findings of small bowel obstruction on abdominal plain films?

A

Two-view plain radiographs should be obtained in all patients with suspected ASBO. Dilated loops of small bowel, presence of air-fluid levels, bowel wall thickening and lack of colonic or rectal air may be seen on X-ray. Paucity of bowel gas can also be seen and may be a more worrisome finding.

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8
Q

What are the radiologic signs and symptoms of bowel ischemia?

A

On plain film pneumoperitoneum is a clear indication of perforation likely secondary to bowel ischemia.

Other concerning findings include bowel wall thickening, pneumatosis intestinalis and portal venous gas. On computed tomography (CT) scan, free peritoneal fluid is also concerning for bowel ischemia [1].

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9
Q

What other imaging modalities aid in the diagnosis of ASBO?

A

The diagnosis of small bowel obstruction (SBO) can often be made by history, physical examination, and abdominal plain films only. CT scan has a sensitivity of 87–92% in diagnosing SBO and can be useful in determining the site and cause of obstruction in children.

However, risks of ionizing radiation and possible need for sedation preclude routine use of CT in children [1].

Administration of oral water-soluble contrast can be used as a diagnostic tool and as a way to predict potential failure of non-operative management.

It may have therapeutic effects in non-operative resolution of ASBO in children [4].

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10
Q

When is CT indicated in pediatric patients suspected of having an ASBO?

A

CT scan can be useful in identifying high grade obstruction with signs of bowel ischemia; however, it is most useful for clinical decision-making when used to differentiate benign from worrisome pneumatosis intestinalis beyond infancy.

Additionally, CT can help differentiate ileus versus SBO in children with concern for concomitant intra-abdominal abscess (for example in the post-appendectomy patient). CT images can then be used to aid in the drainage of these abscesses [1].

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11
Q

Can CT scan be used to predict failure of non-operative management in children?

A

CT findings associated with the need for an operation have been describe in adults, including lack of fecalization of the small bowel, free intraperitoneal fluid, mesenteric edema and the presence of a transition point [1].

However, this has not been specifically studied in children, and CT scan should be used judiciously in children.

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12
Q

When should water soluble contrast studies be used?

A

Children undergoing trial of non-operative management may benefit from upper gastrointestinal series with water-soluble contrast.

Delayed plain films are per- formed at 10 and 24 hours.

These studies should be performed on initial presentation, if they are to be used, in order to limit delay in surgical intervention.

Failure of contrast to reach the colon within 24 hours predicts failure of non-operative management and surgical exploration should then be considered.

Oral administration of water-soluble contrast may improve success rate of non-operative management of ASBO in children [4].

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13
Q

Which patients with ASBO should undergo trial of non-operative management?

A

Children presenting with clinical signs and symptoms of small bowel obstruction who have undergone previous abdominal operation and do not have any of the following: signs of bowel ischemia, hemodynamic compromise or evidence of end-organ distress.

Those with bowel ischemia, perforation, sepsis, and severe physiologic disruption should undergo prompt surgical exploration after appropriate resuscitative measures.

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14
Q

What does non-operative management of ASBO consist of?

A

Initial fluid resuscitation is imperative in all children with SBO.

Standard non-operative treatment of ASBO includes bowel rest, nasogastric tube decompression with a large diameter sump tube, intravenous fluid replacement and correction of electrolyte abnormalities.

An abdominal plain film is the initial imaging
modality of choice when SBO is suspected in children.

Serial abdominal examinations should be performed, ideally by the same examiner.

Analgesics should be administered as needed.

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15
Q

When treating pediatric patients with ASBO non-operatively, how is their progress monitored?

A

Strict monitoring of patient fluid status, urine output and daily nasogastric tube output is imperative.

Serial abdominal exams should be performed.

Water-soluble contrast administration can be used to determine progress of contrast to the colon, predicting successful non-operative management with 96% sensitivity and 98% specificity [4].

If nasogastric tube output does not significantly decrease within 24–48 hours, the abdominal exam worsens, or there are aberrant changes in vital signs, prompt surgical exploration is warranted.

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16
Q

What are the clinical indicators that an ASBO has resolved?

A

Nasogastric tube output will decrease significantly and appear less bilious.

The movement of swallowed air through the GI tract will be evident by the passing of flatus, and resolution of obstipation with a bowel movement.

17
Q

How can nasogastric tube output be falsely elevated?

A

If the distal tip of the nasogastric tube is post-pyloric and within the duodenum, the output will be falsely elevated and frankly bilious.

18
Q

How long should a patient with ASBO be managed non-operatively without improvement?

A

Observation periods greater than 48 hours carry a higher risk of small bowel resection at the time of surgical exploration [1].

Additionally, in patients who have undergone water soluble contrast administration, the failure of contrast to reach the colon within 24 hours is predictive of failure of non-operative management and surgical exploration should be considered [4].

19
Q

What are clinical factors associated with failure of non-operative management?

A

Children less than 1 year of age are more likely to require an operation than older children.

Obstipation, previous ASBO, number of prior abdominal operations, history of a hernia, and history of malignancy are associated with the need for an operation in adults, however this has not been validated in children [1].

20
Q

When should surgical exploration be the initial management choice for ASBO?

A

All children who present with peritonitis, pneumoperitoneum, hemodynamic instability, or findings concerning for bowel ischemia should undergo surgical exploration after resuscitation has been initiated.

21
Q

What role does laparoscopy have in the surgical treatment of ASBO?

A

Laparoscopic surgery has been shown to be a safe and viable option for the surgical management of ASBO, despite initial concerns regarding difficulty with dilated bowel and potential for increased iatrogenic injuries.

Literature suggests that laparoscopy for ASBO reduces morbidity and length of hospital stay compared to laparotomy [5].

22
Q

What are the long-term effects of ASBO?

A

Recurrent SBO is a significant cause of readmission and reoperation in children with previous ASBO.

Infertility in women and chronic abdominal pain in both men and women (24%) who underwent childhood operations account for significant distress, hospital admissions and resource utilization in people with previous ASBO.

23
Q

What is the rate of recurrence of ASBO?

A

ASBO recurs in 9–36% in children as reported in several series [1, 6].

Younger children and those within their first post-operative year may have higher rates of recurrence [4].

24
Q

Is there a difference in recurrence rate of ASBO managed operatively versus non-operatively?

A

Children managed non-operatively have a higher recurrence rate (14–35%) than those managed with an operation (9–19%) [6].

The cumulative rate of recurrence increases over time in adults (18% after ten years and 29% after thirty years), and the risk of ASBO recurrence increases with each successive episode of ASBO [1].

25
Q

Is a small bowel obstruction in the immediate post-operative period managed differently?

A

The mainstay of non-operative management, bowel rest and nasogastric tube decompression, are similar.

Studies in adults suggest that SBO in the immediate postoperative period may be observed for 10–14 days, however in children this has not been specifically supported.

Intussusception is a specific cause of early post-operative bowel obstruction in children, and the majority require surgical exploration.

Therefore, intussusception should be excluded in children prior to attempting prolonged non-operative management in the early post-operative period [1].

Additional consideration should be given to the possibility of incomplete lysis of adhesions as a technical cause of persistent post-operative obstruction.

26
Q

Are there any surgical techniques that can be utilized to decrease the risk of ASBO post-operatively?

A

Neonatal operations have a 13% incidence of ASBO; stoma formation, duration of surgery >1 hour and post-operative complications were risk factors for development of ASBO, and so should be avoided if possible [3].

Gentle surgical technique and minimization of bowel manipulation are standard techniques to prevent ASBO.

Additionally, literature suggest that ASBO rates lower with laparoscopy compared to open surgery [1, 5].

The use of adjuncts such as a bioresorbable membrane composed of sodium hyaluronate and carboxymethylcellulose has been shown to decrease ASBO in adults, and recently in children as well.

Newer products including sprays, gels and liquids have been formulated but not assessed in the pediatric population [7].

27
Q

The commonest worm that causes intestinal obstruction is:

A. Tapeworm.

B. Roundworm.

C. Flukes.

D. Hookworm.

E. Pinworm.

A

B

Roundworm (Ascaris lumbricoides) is the commonest worm that causes intestinal obstruction.

Syed/MCQ

28
Q

Which of the following vitamin deficiency is caused by Ascaris lumbricoides?

A. Vitamin A.

B. Vitamin B1.

C. Vitamin B2.

D. Vitamin B6.

E. Vitamin K.

A

A

Vitamin A.

Syed/MCq

29
Q

Which of the following is a characteristic symptom of Loeffler syndrome is caused by Ascaris lumbricoides?

A. Jaundice.

B. Abdominal pain

C. Bloody stool.

D. Dyspnea.

E. Dysuria.

A

D

Dyspnea.

Ascaris pneumonia (Loeffler syndrome) causes fever, cough and dyspnoea. Sputum is blood-stained and may shows larvae.

Syed/MCQ

30
Q

Which of the following medications is not used to treat Ascaris lumbricoides worm infestation.

A. Albendazole.

B. Mebendazole.

C. Pyrantel Pamoete.

D. Penicillin.

E. Piperazine.

A

D

Penicillin is not useful to treat Ascaris lumbricoides infestation.

Syed/MCQ

31
Q

The commonest site for hydatid cyst formation is:

A. Liver.

B. Lung.

C. Brain.

D. Bone.

E. Heart.

A

A

Liver is commonest site; it is involved in 75 per cent of cases, followed by lung 21 per cent.

Syed/MCQ

32
Q

Sensitivity of indirect haemaglutination test for hydatid cyst is about:

A. 40 percent.

B. 50 percent.

C. 60 percent.

D. 70 percent.

E. 80 percent.

A

E

The sensitivity of indirect haemagglutination (I.H.A) test is about 80 percent.

Syed/MCQ