Somatosensory systems Flashcards

1
Q

What things are sensed by the somatosensory system?

A
pain
touch 
proprioception
itch
visceral (nonpainful stimulus i.e bladder)
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2
Q

What are the 4 stages of sensation

A

transduction
transmission
perception
modulation

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3
Q

What are the classes of neurons that mediate modulation of somatic sensations?

A

dorsal root ganglion neurons

trigeminal sensory neurons

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4
Q

What are the types of neurons in the dorsal root ganglion

A
type A (beta or delta)
type C
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5
Q

Describe type A beta dorsal root ganglionic neurons

A

large, myelinated

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6
Q

Describe type A delta dorsal root ganglionic neurons

A

small, unmyelinated

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7
Q

Describe type C dorsal root ganglionic neurons

A

have schwann cells that just bundle C cells together, not myelinating

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8
Q

What type of dorsal root ganglionic neuron is responsible for pain, temp, itch sensation

A

type C dorsal root ganglionic neuron

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9
Q

What is the difference between slowly adapting and fast adapting neurons?

A

Slow adapting neurons give information on intensity and duration of stimuli by mediating its firing rate (slow = weak stim. fast = strong stim.); fast adapting neurons only transmit when there is a change in strength of stimulus

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10
Q

What is the purpose of two pt discrimination

A

touch your lip with two fingers and touch your thigh with two fingers; it is easier to discriminate between the feeling of each finger on the lips than the thigh

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11
Q

What are the kinds of mechanoreceptors responsible for touch

A

Meissner corpuscle
Merkel cells
Pacinian Corpuscle
Ruffini endings

Phoebe mainly makes rice

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12
Q

What are the superficial mechanoreceptors responsible for touch

A

Meissner corpuscle

Merkel cells

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13
Q

What are the deep mechanoreceptors responsible for touch

A

pacinian corpuscle

ruffini endings

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14
Q

What are the rapidly adapting mechanoreptors

A

Meissner corpuscle

Pacinian corpuscle

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15
Q

What are the slowly adapting mechanoreceptors

A

Merkel cells

Ruffini endings

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16
Q

What are the means of proprioception

A

Joint receptors (sensory receptors in joint + in joint capsule which transduce tension) and muscle receptors (muscle spindles lie parallel to the muscle fibre transducing length + Golgi tendons transduce tension)

17
Q

What neurons transduce hot stimuli

A

A delta axons neurons

18
Q

What neurons transduce cold stimuli

A

C axons (unmyelinated)

19
Q

What neurons transduce dangerous stimuli

A

nociceptors

20
Q

What are the modalities of nociceptors

A
Thermal
Mechanical 
(both A delta fibres)
Polymodal (C fibres)
Silent
21
Q

What determines nociceptor diversity

A

transduction molecule expression on the surface

22
Q

What type of nociceptor causes sensitivity in an area following injury

A

silent nociceptors

23
Q

Describe how A beta fibres bring action potentials to the somatosensory cortex

A

A beta fibres enter the dorsal coloums/medial lemniscal system. Ascending ipsilaterally in the spinal cord and conveys mechanosensory information from the limbs and trunk to the cortex via VPL to the thalamus. Then the second order neuron in the medulla dessucates to the contralateral side and ascends to the thalamus where the third order neuron is located and goes to the somatosensory system.

24
Q

Describe how nociceptors signal the brain

A

through contralateral anterolateral system.

25
Q

What are the divisions of the somatic sensory cortex

A

S1 - primary
S2 - secondary
+ posterior parietal cortex

26
Q

What are the cytoarchitectonic divisions of S1

A

Brodmanns areas 3a, 3b, 1 and 2