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Flashcards in specific toxicity treatments Deck (25):
1

acetaminophen toxicity - treatment

N-acetylcysteine (replenish glutathione)

2

AChE inhibitors, organophosphates toxicity - treatment

Atropine>pralidoxime

3

Antimuscarinic, anticholinergic agonists toxicity - treatment

1. Physostygmine
2. control hyperthermia

4

Amphetamines toxicity - treatment

NH4CL (acidify urine)

5

Arsenic toxicity - treatment

dimercaprol, succimer

6

Benzodiazepines toxicity - treatment

Flumazenil

7

β-blockers toxicity - treatment

saline, atropine, glucagon

8

Carbon monoxide toxicity - treatment

100% 02, hyperbaric oxygen

9

Copper toxicity - treatment

penicillamine, trentine
oral zinc

10

Cyanide toxicity - treatment

Nitrate + thiosulfate, hydroxocobalamin

11

Digitalis (digoxin) toxicity - treatment

Anti-dig Fad fragments

12

Gold toxicity - treatment

penicillamine, diercaprol (BAL), succimer

13

heparin toxicity - treatment

protamine sulfate

14

flumazenil is the antidote for

benzodiazepines

15

iron toxicity - treatment

deferoxamine, derasirox, deferiprone, repeated phlebotomy

16

lead toxicity - treatment

EDTA, dimercaprol, succimer, penicillamine

17

Mercury toxicity - treatment

dimercaprol, succimer

18

Methemoglobin toxicity - treatment

Methylene blue, vitamin C

19

Opioids toxicity - treatment

naloxone

20

Salicylates toxicity - treatment

NaHCO3 (alkalinize urine), dyalisis

21

TCAs toxicity - treatment

NaHCO3

22

Warfarin toxicity - treatment

vitamin K (delayed effect)
fresh frozen plasma (immediate)

23

Bivalirudin toxicity - treatment

not specific --> can attempt to use activated prothrombin complex concentrates (PCC) and/or fibrinolytics (eg. traxenamic acid)

24

Methanol, ethynele glycol (antifreeze) toxicity - treatment

fomepizole>ethanol, dialysis

25

arsenic, copper, gold, iron, lead, mercury toxicity - treatment

arsenic --> dimercaprol, succimer
copper --> penicillamine, trentine, oral zinc
lead --> EDTA, dimercaprol, succimer, penicillamine
gold --> penicillamine, diercaprol (BAL), succimer
mercury --> dimercaprol, succimer
iron --> deferoxamine, derasirox, deferiprone, repeated phlebotomy