Stable Angina Flashcards

1
Q

What is Stable Angina?

A

Chest Pain which is activity or emotion induced to increased myocardial demand

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2
Q

Name some risk factors for stable angina?

A

Hyperglycemia and Postmenopausal Females

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3
Q

Before starting statins what blood test should you do?

A

LFTs

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4
Q

Before starting ACE inhibitors which blood test should you do?

A

U+E’s

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5
Q

What does GTN Spray do?

A

Relaxes smooth muscle due to NO stimulating cGAMP

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6
Q

Which first line medications should be used for stable angina?

A

Beta Blocker and Calcium Channel Blocker

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7
Q

What is beta blockers action?

A

Decrease HR, Systolic Wall Tension and Vasodilate

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8
Q

What are common contraindications to Beta blocker use? (6)

A

Asthma
Peripheral Vascular Disease
Raynauds Syndrome
Heart Failure
Existing Bradycardia/Heart Block

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9
Q

Name some common adverse drug reactions to Beta Blockers? (5)

A

Tired
Impotence
Bradycardia
Bronchospasm
Rebound

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10
Q

Which medication should you never use with Verapamil and why?

A

Beta blockers due to risk of complete heart block

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11
Q

Name three calcium channel blockers which can be used in Stable Angina?

A

Diltiazem
Verapamil
Amlodipine

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12
Q

Which 2nd line medication can be used if a patient does not tolerate beta blockers and ccb’s in stable angina?

A

Ivabradine

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13
Q

What is Nicorandil?

A

Potassium channel activator

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14
Q

Which medication used in stable angina has a negative inotropic action?

A

Nicorandil

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15
Q

Name a common side effect of Nicorandil?

A

Ulcers which can perforate

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16
Q

What does Ranolazine do in Stable Angina?

A

Sodium Current inhibitor

17
Q

Ranolazine inhibits CYP2D6 therefore should not be used with what medications? (2)

A

Clarithromycin
Ketoconazole

18
Q

How do you prevent nitrate tolerance in Stable Angina?

A

Assymetric dosing regimen of Isosorbide Mononitrate

19
Q

Which calcium channel blocker is long acting?

A

Nifidipine

20
Q

Name a long acting nitrate?

A

Isosorbide Mononitrate

21
Q

What secondary prevention should patients with Stable Angina be started on? (3)

A

Aspirin
Atorvastatin
Ace Inhibitor