STDs Flashcards
(23 cards)
Classification of STDs
Incidence of HPV
It is the most common viral STD
Causative Organism of HPV
caused by DNA Popova virus.
Sites affected by HPV
affects the vuvla, vagina, cervix, perineum and anus as condyloma accuminata (genital warts).
Types & Pathologies of HPV
- Types 16 &18 cause flat warts with the risk of CIN.
- Types 6 &11 cause exophytic warts with no malignant potential.
CP of HPV
- The characteristic lesion is genital wart which may be single or multiple.
Dx of HPV
- Direct demonstration of virus: by electron microscopy
- Detection of viral Ag
- PCR
- Viral isolation: on tissue culture.
- Pap smear: Koilocytosis may present [some cells with atypia or dysplasia]. ⭐️
- Colposcopy: mandatory for all cases to exclude atypical cells. ⭐️
TTT of HPV
- Small lesion: Topical podophyllin, trichloroacetic acid or 5-fluorouracil.
- Large lesion: Cryotherapy, electrocautery or laser therapy
Causative Organism of Gonorrhea
Neisseria gonorrhea (gram –ve intracellular diplococci)
CP of Gonorrhea
- It affects areas lined by thin epithelium (columnar OR transitional) not stratified epithelium.
- It may cause urethritis, Bartholinitis, cervicitis, salpingitis (PID) or arthritis (via blood spread).
- Burning urination, frequency, dysuria with urethritis.
- Discharge with Bartholinitis or cervicitis OR even picture of PID.
INVx of Gonorrhea
- Direct demonstration of organism: by Gram stain.
- Culture and sensitivity: On Thayer martin or chocolate agar. ⭐️
- Serology: Detection of Abs in patient’s serum.
TTT of Gonorrhea
Penicillin or cephalosporins.
CO of lymphogranuloma venereum
chlamydia trachomatis, the commonest STD in sexually active women.
Characters of chlamydia trachomatis
It is obligate intracellular organism between viruses & bacteria.
Sybtypes of chlamydia trachomatis
- It is of 15 serotypes.
- Serotypes L1, L2, L3 cause lymphogranuloma venereum (LGV)
- Serotypes D, E, F, G, H, I, J, K cause genital infections other than LGV as urethritis, Bartholinitis, cervicitis, endometritis & salpingitis (PID).
Phases of lymphogranuloma venereum (LGV)
Phases of lymphogranuloma venereum (LGV)
- 1ry
shallow painless ulcer on labia.
Phases of lymphogranuloma venereum (LGV)
- 2ry
Phases of lymphogranuloma venereum (LGV)
- 3ry
- rupture of buboes, formation of multiple sinuses & fistulas discharging pus.
CP of Lymphogranuloma venereum (LGV)
Clinical manifestations according to the phases mentioned before.
INVx for Lymphogranuloma venereum (LGV)
Direct demonstration of organism: by detection of chlamydial Ag by monoclonal Abs via ELISA (the test of choice).
Culture: tissue culture.
TTT of Lymphogranuloma venereum (LGV)
Doxycycline
