STI II Flashcards
Compare and contrast primary, secondary, and tertiary syphilis. Discuss the value and specificity of screening tests for syphilis. Diagnose vaginal infections with Candida. Diagnose vaginal infections with Trichinella. Identify common microbial agents in vaginosis.
distinguishing charecteristics of treponema
outer envelope, slime layer
treponema palliadium causes
syphillis
main virulance factor of treponema palliadium
slime layer
protoplamic cylinder
body of treponema
stain for treponema
silver stain
cultivation medium for treponema
rabbit testes
source of treponema palliadium infection
skin lesion with bacteria in contact with abraded skin or mucous membrane
incubation period of treponema palliadium
10-60 days
visible painless crater-like ulcer
chancre
outcome of chancre
heals in 1-6 weeks, but leads to baceriemia
generalized skin rash and generalized lymphadenopathy with fever and headache
2ndary syphillis
location of secondary syphilys rash
hands and feet
internal secondary syphillis lesion locations
kidney and bone
most infectious syphllis lesion type
secondary
is pt infectious during latent syphillis?
no
manifestations (3) of tertiary syphillis
gummas
neurosyphillis
CV syphillis
sx of neurosyphilis
blindness, sezieures and paralytic dementias
manifestations of CV syphillis
aortic and pulmonary artery arteritis abt stenosis
route of congenital syphillis infections
from placenta, 1st trimester
signs of congenital syphillis
hepatosplenomegaly, jaundice, hemolytic anemia, pneumonia, and long bone involvement
treatment for primary, secondary and early latent syphillis
penicillin
treatment for tertiary syphillis w/o neuro involvement
penicillin
tx for syphillis if penicillin allergic
doxy or tetra
jarisch-herxheimer reaction
acture febrile response folloing early treatment of syphillis in response to sudden release of large amount of killed orginsms
