uterus Flashcards

Describe the common functional endometrial disorders (causes of AUB and DUB) Describe acute and chronic endometritis and the common causes and clinical associations. Describe the proposed causes and complications of endometriosis Describe adenomyosis and its associated clinicopathologic findings Describe endometrial polyps (symptoms, causes, outcomes) Describe the endometrial hyperplasia / carcinoma sequence Describe the common malignant tumors of the endometrium (endometrioid, clear cell (42 cards)

1
Q

bleeding due to alteration in the normal cyclical hormonal stimulation of the endometrium

A

dysfunctional uterine bleeding

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2
Q

causes of dysfunctional uterine bleeding

A

faiulre of ovulation
inadequate luteal phase
OCPs
menopausal changes

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3
Q

bleeding causes that are not considered dysfunctional uterine bleeding

A

polyp
hyperplasia/Carcinoma
endometriosis

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4
Q

causes of anovulatory cycles

A

excess estrogen

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5
Q

dysfunctional uterine bleeding associated with infertility and pregancy loss

A

inadequate luteal phase

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6
Q

dysfunctional uterine bleeding with low progesterone

A

inadequate luteal phase

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7
Q

endometriosis with neutrophils

A

acute

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8
Q

endometriosis with plasma cells

A

chronic

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9
Q

causes of acute endometriosis

A

birth, miscarrage, strep infection after retained products of conception

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10
Q

causes of chronic endometriosis

A

gonorrhea, chlamydia, IUD

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11
Q

most common locations of endometriosis

A

ovaries, pouch of douglas, peritoneal surfaces

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12
Q

likely cause of endometrosis

A

menstrual backflow through fallowian tubes

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13
Q

“chocolate cysts” and blood filled macrophages

A

endometriosis

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14
Q

growth of the endometrium into the mymetroum

A

adenomysosis

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15
Q

round muscular mass in uterus

A

adenomysosis

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16
Q

treatment for adenomysosis

A

hysterectomy

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17
Q

associated with tamifloxin

A

endometrial polyps

18
Q

chance endometrial polyps develops into cancer

A

very very slight

19
Q

time endometrial polyps develop

A

menopause most common

20
Q

presents with abnormal postmenipausal bleeding

A

endometrial hyperplasia

21
Q

endometrial hyperplasia with high risk of cancer

A

complex hyperplasia with atypia

22
Q

cancer risk of complex hyperplasia with atypia

23
Q

histological sign of complex hyperplasia

A

atypical glands and more glands than stroma

24
Q

most common female GU tract cancer

A

endometrial carcinoma

25
bigest risk for endometrial carcinoma
long term use of high-dose post menopausal estrogens
26
most commin presentation of endometrial carcinoma
post-menopausal bleeds
27
genetic mutation in endometrioid adenocarcinoma
PTEN
28
gebetic mutation in papillary carcinoma
p53
29
endometrial carcinoma automatically considered high grade
clear cell
30
pasmmomoa bodies
serous adenocarcinoma (epithelial)
31
adenocarcinoma of uterus spreads to
cervix
32
serous endometrial carcinoma spreads to
pevis and abdomen
33
treatment for adenocarcinoma of uterus
radiation
34
treatment for serous endometrial carcinoma
chemo
35
benign smooth muscle tumor of uterus
leimyoma
36
common name for leimyoma
fibroid
37
presentation of submucosal leiomyoma
menorrhagia
38
presentation of subserosal leiomyoma
constipation and urinary urgency
39
intersecting fascicles of begnin smooth muscle cells
leiomyoma
40
most common sarcoma of uterus
leiomyosarcoma
41
outcome for leiomyosarcoma
poor
42
microscopy of leiomyosarcoma
increased cellularity, mitotic figures, cogaulative necreosis