STIs Flashcards
(102 cards)
1
Q
symptoms of urethritis (ngonorrheae, ctrachomatis)
A
dysuria
frequency
purulent or mucopurulent discharge
minimal or asymptomatic
2
Q
symptoms of cervicitis (ngonoorheae, ctrachomatis)
A
purulent discharge
endocervical bleeding
asymptomatic
3
Q
symptoms of genital ulcer disease
A
ulcer on genitalia
4
Q
prostatitis (prostate gland infection) symptoms
A
dysuria
bloody urine
lower back pain
pain testes/penis
5
Q
what is pelvic inflammatory disease
A
ascending spread of pathogens from vagina to upper female genital tract
6
Q
symptoms of PID
A
abd/pelvic pain cervical motion tenderness vaginal discharge fever elevated WBC intermenstrual bleeding
7
Q
define serology
A
measures/detects antibodies to pathogen
8
Q
most common STIs
A
gonorrhea
chlamydia
syphilis
trichmoniasis
9
Q
which STIs are reportable to MB health
A
gonorrhea chlamydia syphilis hep b hep c HIV
10
Q
people wiht gonorrhea may be co infected with
A
chlamydia
11
Q
NAAT
A
nucleic acid amplification test PCR detects specific DNA sequence of pathogen
12
Q
DFA
A
diract fluorescent antigen
13
Q
serology
A
measures/detects antibodies to pathogen
14
Q
patients with syphillis may be coinfected with what
A
HIV
15
Q
name some risk factors for stis
A
unprotected sex MSM age geographic sex worker gender unaware anonymous sex
16
Q
some impact of stis
A
complications PID dmage to reporductive tract transmission antibiotic resistance economic congenital infections
17
Q
which is the only sti greater in males
A
syphilis
18
Q
sti patient education
A
risks of untreated infection/reinfection abstain from sex 3 days after treatment barrier protection return to care if symptoms not improved get tested reduce risks of sexual activity
19
Q
most common infection of gon
A
urethrutus
cervicitis
20
Q
other tyoes of gon infection
A
oropharyanx
ocular
diffeminated gonococcal infection
neonatal conjunctivitis
21
Q
incubation of gon
A
1-14 day
22
Q
male symptoms of gon
A
symptomatic common
urethral - dysuria, frequency
anorectal - pain
pharyngeal - pharyngitis
23
Q
female symptoms of gon
A
asymptomatic or min symptomatic
urethral: dysuria, frequency
anorectal pain
pharyngeal- pharyngitis
24
Q
signs of gon
A
urethral, rectal, or vaginal discharge
adnormal vag discharge or uterine bleeding
25
male complications of gon
```
epidiymitis
prostatitis
urethral stricture
inguinal lymphadenopathy
DGI
```
26
female complication of gon
PID
ectopic pregnancy
infertility
27
what is disseminated gon infection
ngon bacteremia seeds sites outside reproductive tract
fever, chills, joint pain, skin rash
if go to other organs ex. meningitis
28
symptoms of neonatal conjunctivitis
infection may lead to blindness
29
prevention of neonatal conjunctivits
erythromycin 0.5% eye ointment applied to newborns as prophylaxis
30
labs for gon
gram stain - gram negative diplococci
culture
NAAT
31
major concern for gon
antibiotic resistance
32
which antibiotics is gon completely resistant to
penicillin
ampicillin
fluoroquinolones - only use if local resistance <5%
33
what do you also treat for in gon
chlamydia due to high rate of concomitant infection
34
treatment of uncomplicated gon
ceftriaxone and azithromycin single dose
35
alternative treatment for uncomplicated gon
azithromycin single dose
| cefixime and azithro
36
what should you do when monotherapy with azithromycin is use
test of cure
37
anogenital infection gon infection in <9yoa
cefixime and azithromycin
ceftriaxone and azithro
no alternative
38
pharyngeal infection treatment for <9yoa
ceftriaxone and azithro
| alternative: cefixime and azithro
39
why dont we use macrolide in children under 1 month
pyloric stenosis
40
treatment of gon opthalmia and disseminated infection
ceftriaxone and azithro
41
what gon infections require hospitalization
meningitis and disseminated
| any disseminated infection if under 9
42
treatment for ophthalmia neonatorum
ceftriaxone
irrigate eyes hourly
test for chlamydia (no prophylaxis)
hospitalization and consult with expert
43
anogenital gon alternative treatment if contraindication to cephalosporins and macrolide resistance
gentimicin iv or im plus azithromycin or doxy
44
when should you repeat screening in someone with a gon infection
6months after treatment
45
when do you test for cure for ngon
```
pharyngeal infections
presistant symptoms
alternative treatment
reexposure
pregnancy
disseminated
child
abortion
AM resistant
```
46
symptoms of PID
lower ab pain
irregular menstrual bleeding
fever
pain with intercourse and urination
47
complications of PID
tuboovaria abscess
infertility
extopic pregnancy
chronic pelvic pain
48
chlamydia pathogen
gram negative obligate intracellular pathogen
49
chlamydia incubation
35 days
50
chlamydia onset
7-21 days
51
sites of chlamydia infection
```
endocervical canal
urethra
oropharynx
rectum
eye
```
52
chlamydia sigs in symptoms in men
```
often asymptomatic
dysuria
discharge
pharyngitis
rectal pain discharge bleeding
```
53
chlamydia signs and symptoms in women
subclinical
pharyngitis
discharge
uterine bleeding
54
male complications of chlamydia
epididymitis
| reiters syndrome
55
female complications of chlamydia
PID
ectopic pregnancy
infertility
reiters
56
newborn exposure to chlamydia can result in
neonatal conjunctivitis
| pneumonia
57
diagnosis of chlamydia
NAAT
DFA
culture if treatment failure
symptoms and history
58
treatment options for uncomplicated urethral endocervical rectal and conjunctival infections in >9yoa
azithromycin one dose
| doxy 7 days
59
treatment option for chlamydia in children
azithro
| erythromycin
60
treatment option for chlamydia in pregnant women
azithro - weigh risk ad benefit
erythro
amox if cant tolerate either
61
pathogen in syphilis
treponema pallidum spirochete
| invades humans only through mucous membranes or open lesions
62
co infection of syphilis and ____ is common
HIV
| consult with specialist
63
describe primary syphiliis
genitalia, perianal, mouth, throat
chancre, regional lymphadenopathy
incubation 3 weeks
64
describe secondary syphilis
multisystem
rash, fever, malaise, mucous lesions, alopecia, meningitis..
incubation 2-12 weeks
65
describe latent syphilis
multisystem dormant
| asymptomatic
66
describe tertiary syphilis
cardiovascular - aortic aneurysm, coronary artery stenosis, 10-30years
neurosyphilis - vertigo, personality changes, 2-20 years
gumma - tissue destruction of any organ, 15 years
67
syphilis in newborns
tpallidum can cross placenta, highest risk when mom in primary/secondary
screen for signs of early congenital syphilis
68
diagnosis of syphilis
history and cliinical presentation
dark field microscopy
NAAT
serologic - treponemal, non treponemal
69
treatment of primary, secondary, and early latent <1 yr duration syphilis
benzathine penicillin IM single dose
alternative: doxycycline PO 14 days
ceftriaxone IV 10 days
70
treatment of late latent or unknow duration latent and tertiary (not involving CNS) syphilis
benzathine penicillin IM 3 doses
| alternative: penicillin desensitization, doxy for 28 days, ceftriaxone IV for 10 days
71
treatment of neurosyphilis
pen G x10-14 days
| alternative: penicillin desensitization followed by penicillin, ceftriaxone IV x 10-14d
72
treatment of sexual contacts in prior 90 days to syphilis
pen G single dose IM
73
treatment of syphilis in pregnant women
pen G IM
| consider pen desensitization followed by treatment with pen
74
trichomonas pathogen
trichomonas vaginalis
flagellated motile protozoan
humans only host
75
incubation time for trichmonas
3-28 days
| detectable 48hr after exposure
76
sites of trichomonas infection
```
urethra
endocervical canal
rectum
oropharynx
eye
```
77
signs and symptoms of trichomonas in males
asymptomatic (more common than in females)
urethral discharge
dysuria, pruritis
78
signs and symptoms of trichomonas in women
```
asymptomatic
malodorous vag discharge and pruiritis
dysuria, dyspareunia
vag ph 4.5-6
inflammation of vulva/vagina/cervix
urethritis
```
79
male complication of trichomonas
epididymitis and chronic prostatitis
| male infertility
80
female complications in trichomonas
PID
premature labor
premature rupture of membranes, low birth weight infants
cervical neoplasia
81
diagnosis of trichomonas
history
presentation
NAAT
microscopy
82
treatment of trichomonas
metronidazole single dose of 7 days
intravaginal metronidazole is not effective
metronidazole not CI in pregnancy or breast feeding
83
efficacy of trichamonas treatment
88% increase to 95% if partner also treated
84
infection sites of HPV
moist mucose of anogenital tract, oral cavity and oropharynx
| non mucosal causes warts on hands and feet k
85
describe hov type 6 and 11
low risk
| cause anogenital warts
86
describe HPV 16 and 18
high risk
| cause cervical cancer
87
prevention of HPV
condoms
counselling
screening
HOV vaccination
88
describe gardisal
approved for females 9-45 and males 9-26
| 3 doses at 0,2,6 months
89
describe gardisil 9
4 HPV types added
90
describe ceravix
used for females 9-45
| 3 doses at 0, 1, 6 months
91
treatment of HPV
see specialist
92
difference between HSV 1 and 2
1 - oropharyngeal and genital disease
| 2- genital disease
93
5 stages of HPVinfection
```
primary mucocutaneous
ganglia
latency
reactivation
recurrent infection
```
94
difference between 1st episode primary and non primary
primary - HSV antibody negative individual
| non primary - HSV + antibody, prior exposure
95
diagnosis of HSVC
```
history
presentation
electron microscopy
tissue culture
NAAT
immunoflourescence assay
```
96
treatment of HSV
no cure
antivirals acyclovir, famciclovir, valacyclovir modify course
first episode antiviral reduce shedding and duration
recurrent can treat when prodrome or continuously suppressive to reduce frequency
97
HSV incubation
2-14 days
98
1st episode of HSV signs and symptoms
usualy asymptomatic
multiple painful lesions of external genitalia develop in a week and heal in 2-4 weeks
flu like symptoms
itching, pain, discomfort, discharge
99
how long does shedding of HSV occur for
primary 11-12 days, nonprimary 7 days
| recurrent 4 days
100
in which people are HSV symptoms more severe
females
IC
primary infection
101
sings and symptoms of recurrent HSV
prodrome - itching, burning, tingling
fewer lesions, milder
asymptomatic viral shedding during first year of infection
102
complications of HSV
```
secondary infection of lesions
extragenital infection because of autoinoculation
disseminated
meningitis
encephalitis
neonatal transmission
```
