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Flashcards in Streptococcus Pyogenes Deck (18):
1

Describe the microbiology of strep pyogenes

- gram positive cocci
- arranged in chains
- group A streptococcus
- facultative

2

What are the virulence factors of strep p?

- bacterial capsule
- exotoxin production (e.g. Streptolyisn S) and immune evasion
- dissemination

3

What are the common strep p infections?

- sore throat
- cellulitis
- scarlet fever
- meningitis
- pneumonia

4

When is it more likely to get a sore throat?

Spring and autumn

5

What are the signs and symptoms of sore throat?

- swollen tonsils
- painful
- tender
- discomfort when swallowing

6

What are the differential diagnoses of sore throat?

- Glandular fever: viral infection
- Cancer: persistent sore throat
- Quinsy: painful collection of pus
- Epiglotittis: inflammation of epiglottis

7

What are the danger symptoms of sore throat?

- persistent high temp
- symptoms for longer that 4-5 days
- difficulty swallowing or breathing

8

What is the treatment for sore throat?

OTC analgesics and antibiotics
- Carbimazole
- DMARDS

9

What are the complications of Group A Strep infections?

- acute rheumatic fever
- rheumatic heart disease
- post streptococcal glomerulephritis
- bacteraemia / septicaemia
- necrotising fasciitis
- TSS

10

What is the aetiology of cellulitis?

- obese
- weakened immune system
- poorly controlled diabetes / circulation problems
- chickenpox or shingles
- lymphoeddema
- IV drug use
- previous episodes of cellulitis

11

What are the endogenous carriers of Gp A streptococci?

- interdigital toe spaces
- vagina
- anus

12

What are the signs and symptoms of cellulitis?

- skin becomes red, swollen, tender and pain fully.
- mainly affects legs
- blisters

13

What are the differential diagnosis for cellulitis?

- eczema
- lymphoedema
- allergic reaction

14

What are the danger eliminations for cellulitis?

- rapid spread of redness in an area
- high temp
- changes in mental state
- rapid heart beat / breathing
- nausea / vomiting

15

What is the treatment for mild/moderate cellulitis infections?

7-14 days antibiotics at home
- Phenoxymethylpenicllin (clarithromycin / clindamycin)

16

What is the treatment for advanced cellulitis infection?

IV benzylpenicillin (vancomycin)

17

What are the complication of cellulitis?

- bacteraemia / septicaemia
- necrotising fasciitis
- abscess
- facial cellulitis
- meningitis

18

What is the role of a pharmacist in the management of cellulitis?

they should pick up on danger symptoms, give OTC pain relief and advise patients to keep affected leg raised